Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Results from STEALTH C-3 clinical trial of nitazoxanide presented at DDW 2010

Romark Laboratories announced results from its STEALTH C-3 clinical trial, a phase 2 clinical study of nitazoxanide in treatment-naive patients with genotype 1 chronic hepatitis C. Study results were presented this afternoon as an oral communication at a late breaking forum of the American Gastroenterological Association Institute during Digestive Disease Week 2010 in New Orleans, Louisiana.

5 May 2010

Idera Pharmaceuticals reports net loss of $1.9M for first-quarter 2010

Idera Pharmaceuticals, Inc., a biotechnology company engaged in the discovery and development of DNA- and RNA-based drug candidates targeted to Toll-like Receptors, today reported financial results for the first quarter ended March 31, 2010.

5 May 2010

Study comparing enteroscopy technologies finds SE quicker than DBE for examining small intestine

Spirus Medical, Inc., a leading developer of diagnostic and therapeutic advancement systems for gastroenterology, announced at Digestive Disease Week 2010 that results from the first-ever prospective study comparing enteroscopy technologies show spiral enteroscopy (SE) to be more than three times faster, on average, than double-balloon enteroscopy (DBE) in examining the small intestine.

4 May 2010

Shorter shifts for endoscopists positively influence polyp detection rates

A shorter daily shift schedule for endoscopists, the physicians who perform colonoscopies, avoids a decrease in the polyp detection rate as the day progresses, research from Mayo Clinic indicates. The findings, which have implications for endoscopist scheduling, were presented by Mayo Clinic investigators today at Digestive Disease Week 2010, (http://www.ddw.org/wmspage.cfm?parm1=679) the annual meeting of the American Gastroenterological Association.

4 May 2010

UCB, IBDWG announce recipients of 2010 Research Awards in IBD for GI Fellows

UCB and the Inflammatory Bowel Disease Working Group today announced the five recipients of the 2010 Research Awards in Inflammatory Bowel Disease for Gastroenterology Fellows, each of whom will receive a one-year $40,000 research grant for their original clinical or basic research.

4 May 2010

Ocera Therapeutics presents Phase 2 proof-of-concept study results of AST-120 in non-constipating IBS

Ocera Therapeutics, Inc. presented results yesterday from a Phase 2 proof-of-concept study of AST-120 (spherical carbon adsorbent) in the treatment of patients with non-constipating Irritable Bowel Syndrome (IBS) at DDW, the annual meeting of the American Gastroenterological Association. Data showed that subjects treated with AST-120 responded in a consistent manner with reduction in pain better than placebo at week four and at week eight, the primary time point for analysis. The company plans to initiate a Phase 2b study evaluating AST-120 in non-constipating IBS.

4 May 2010

Doctors often treat IBS patients with narcotics: Researchers

Doctors often unnecessarily treat irritable bowel syndrome with narcotics, according to a study led by University of North Carolina at Chapel Hill researchers.

4 May 2010

ACAAI, AGA Institute announce innovative initiative to raise awareness of HAE

The American College of Allergy, Asthma and Immunology and the American Gastroenterological Association Institute today announced an innovative initiative called "HAE: Learn About It, Talk About It," at Digestive Disease Week® 2010.

4 May 2010

Weight loss through caloric restriction and increase in physical activity improve symptoms of GERD

Gastroesophageal reflux disease (GERD) is a debilitating problem for sufferers -- heartburn, difficulty swallowing, chest pain and acid reflux. According to a Mayo Clinic study that will be presented at Digestive Disease Week (DDW) 2010 in New Orleans May 1-5, even moderate weight gain can exacerbate those symptoms, DDW is the largest international gathering of physicians and researcher in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

3 May 2010

Ethicon Endo-Surgery SEDASYS CAPS system receives European Union CE Mark, Health Canada approval

Ethicon Endo-Surgery today announced that the SEDASYS® System, the first computer-assisted personalized sedation (CAPS) system, was granted a CE Mark for the European Union for routine colonoscopy and screening of the upper gastrointestinal tract (EGD procedures), and Health Canada granted regulatory approval for the SEDASYS® System for use by healthcare professional teams during routine colonoscopy.

3 May 2010

TGRD presents positive results from Phase 3 studies of azilsartan medoxomil for lowering SBP at 25th ASH

Takeda Global Research & Development Center, Inc., U.S., (TGRD U.S.) today announced results from pivotal phase 3 studies of azilsartan medoxomil (development code: TAK-491), an angiotensin II receptor blocker (ARB), demonstrating greater 24-hour systolic blood pressure (SBP) reduction compared to commonly prescribed ARBs olmesartan medoxomil and valsartan.

3 May 2010

Extended hepatitis C treatment increases sustained virological response after liver transplant

Extending hepatitis C treatment for liver transplant patients beyond current standards results in high clearance rates of the hepatitis C virus from the blood, and a low relapse rate, according to a study by Henry Ford Hospital.

3 May 2010

Researchers explore use of nanomedicine techniques for treatment of diseases in children

"Children are not small adults"—pediatricians say that's what makes their specialty different from the practice of medicine in adults. For similar reasons, researchers exploring the medical uses of nanotechnology believe that the use of molecular-level nanomedicine techniques in children will also require its own specialty.

3 May 2010

Study indicates older women with diabetes have increase risk for colon cancer

A research team led by Mayo Clinic physicians has found that older women with diabetes face a more than doubled risk for some types of colorectal cancer.

3 May 2010

Ipsen's first-quarter 2010 drug sales up 6.2%

Ipsen reported today its sales for the first quarter 2010.

3 May 2010

Measuring children's blood pressure is complicated: Researchers

A Johns Hopkins Children's Center study of 2,500 patient records suggests that medical staff fails to check a child's blood pressure a fifth of the time, and is not recognizing what constitutes an abnormal reading in those whose blood pressure they do check.

3 May 2010

VIMOVO delayed-release tablets receive FDA approval

AstraZeneca and POZEN Inc. today announced the U.S. Food and Drug Administration has approved VIMOVO (naproxen and esomeprazole magnesium) delayed-release tablets for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.

3 May 2010

Health outcomes explored at DDW 2010

Non-alcoholic fatty liver disease, which may soon be the leading indication for liver transplant, is found to be significantly associated with worse transplant outcomes. In addition, a new tool for diagnosing NAFLD represents an alternative to liver biopsy, which is more expensive and prone to complications, and ultrasound and alfafeprotein blood test screening are an effective alternative to CT scan and MRI for patients with cirrhosis at high risk for hepatocellular cancer.

3 May 2010

Vitamin E effective in treating NASH: Study

Vitamin E has been shown effective in treating nonalcoholic steatohepatitis, an obesity-associated chronic liver disease that can lead to cirrhosis, liver cancer, and death. NASH also is related to or a part of type 2 diabetes, lipid disorders and cardiovascular disease.

3 May 2010

Boston Scientific to present multiple clinical abstracts on its endoscopy products at DDW 2010

Boston Scientific Corporation today announced that multiple clinical abstracts examining the diagnostic and therapeutic utility of its SpyGlass Direct Visualization System, Radial Jaw 4 Biopsy Forceps and WallFlex Duodenal Stent will be presented at Digestive Disease Week, May 1 – 5 in New Orleans.

30 Apr 2010

Gastroenterology News and Research

Further Reading

Results from STEALTH C-3 clinical trial of nitazoxanide presented at DDW 2010

Idera Pharmaceuticals reports net loss of $1.9M for first-quarter 2010

Study comparing enteroscopy technologies finds SE quicker than DBE for examining small intestine

Shorter shifts for endoscopists positively influence polyp detection rates

UCB, IBDWG announce recipients of 2010 Research Awards in IBD for GI Fellows

Ocera Therapeutics presents Phase 2 proof-of-concept study results of AST-120 in non-constipating IBS

Doctors often treat IBS patients with narcotics: Researchers

ACAAI, AGA Institute announce innovative initiative to raise awareness of HAE

Weight loss through caloric restriction and increase in physical activity improve symptoms of GERD

Ethicon Endo-Surgery SEDASYS CAPS system receives European Union CE Mark, Health Canada approval

TGRD presents positive results from Phase 3 studies of azilsartan medoxomil for lowering SBP at 25th ASH

Extended hepatitis C treatment increases sustained virological response after liver transplant

Researchers explore use of nanomedicine techniques for treatment of diseases in children

Study indicates older women with diabetes have increase risk for colon cancer

Ipsen's first-quarter 2010 drug sales up 6.2%

Measuring children's blood pressure is complicated: Researchers

VIMOVO delayed-release tablets receive FDA approval

Health outcomes explored at DDW 2010

Vitamin E effective in treating NASH: Study

Boston Scientific to present multiple clinical abstracts on its endoscopy products at DDW 2010

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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