Gastrointestinal Tract News and Research

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Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

In an intensive look at the effects of the virus causing COVID-19 on patients' microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.

28 Nov 2022

Study: Nearly 1 in 7 Americans regularly experience bloating issues

Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study led by Cedars-Sinai investigators.

24 Nov 2022

KEMEPHY diet may be an effective dietary pattern for athletes

Scientists have characterized the effects of the ketogenic Mediterranean diet with phytoextracts on gut microbiota composition in athletes. The study by researchers in Italy and Spain is published in the journal Frontiers in Nutrition.

21 Nov 2022

Augmented drug preferentially eliminates cancer cells but does not harm healthy cells

Johns Hopkins Medicine researchers have revamped an anti-cancer drug to better target cancer cells and leave healthy tissues unharmed. Scientists have dubbed this type of targeted approach a "prodrug" -; a medicine designed to release its payload in a particular area of the body and in no other areas.

17 Nov 2022

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Clostridioides difficile, often referred to as C. difficile or C. diff, is a bacterium that causes severe intestinal illness and, as its name suggests, can be difficult to study and treat.

16 Nov 2022

Gene may play a broader role in embryonic organ development

An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result.

15 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body.

2 Nov 2022

Study finds possible treatment strategy for Feingold syndrome type 1

A decrease in protein synthesis in cells of the developing gut contributes to a rare genetic disorder, and an inexpensive nutritional supplement may help reverse that decrease, according to a new study publishing November 1st in the open access journal PLOS Biology by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues. The finding is an advance in understanding the pathogenesis of the disease, and may lead to new treatments.

2 Nov 2022

Researchers study the unique adaptability of small intestinal bacteria for the first time

Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing.

1 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

New probe design offers promises for many imaging applications in biological and biomedical research

Microendoscopes are the cornerstone of modern medical diagnostics - they allow us to see what we could not even describe two decades ago.

28 Oct 2022

Using stem cell cloning to identify the origin of lethal stomach and esophageal cancers

The University of Houston is leading a team of cancer researchers and experts in stem cell cloning to identify the origin of two very lethal cancers of the stomach and esophagus - esophageal adenocarcinoma (EAC) and intestinal gastric cancer (iGC).

27 Oct 2022

Probiotics and prebiotics can reduce the risk of frailty syndrome among the elderly

New research found that the intestinal microbiome plays a critical role in the metabolic processes that affect cognition, body composition, and immune function.

26 Oct 2022

Engineered particles of purified sand could be a potential cure for obesity

Engineered particles of purified sand could be the next anti-obesity therapy as new research from the University of South Australia shows that porous silica can prevent fats and carbohydrates from being adsorbed in the body.

25 Oct 2022

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

According to a recent study, substance P produced by the nociceptors present in the gut lining confers protection against inflammation and tissue damage by increasing the number of beneficial microbes.

19 Oct 2022

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Ulcerative colitis is the most common type of inflammatory bowel disease, characterised by chronic ulcers and inflammation in the colon and rectum.

18 Oct 2022

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Colonic motility disorders, especially problems associated with constipation and diarrhea, are common in adults and children, greatly impacting quality of life.

11 Oct 2022

Can surveillance of SARS-CoV-2 be conducted through aircraft wastewater analysis?

Research investigates the behavior of air travelers, especially those who had flown during the pandemic.

6 Oct 2022

Gastrointestinal Tract News and Research

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

Study: Nearly 1 in 7 Americans regularly experience bloating issues

KEMEPHY diet may be an effective dietary pattern for athletes

Augmented drug preferentially eliminates cancer cells but does not harm healthy cells

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Gene may play a broader role in embryonic organ development

Circadian disruption induces weight gain through changes in gut microbiota

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Study finds possible treatment strategy for Feingold syndrome type 1

Researchers study the unique adaptability of small intestinal bacteria for the first time

First preclinical model to study the pathobiology of appendiceal cancer

New probe design offers promises for many imaging applications in biological and biomedical research

Using stem cell cloning to identify the origin of lethal stomach and esophageal cancers

Probiotics and prebiotics can reduce the risk of frailty syndrome among the elderly

Engineered particles of purified sand could be a potential cure for obesity

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Can surveillance of SARS-CoV-2 be conducted through aircraft wastewater analysis?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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