Gene Editing News and Research

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Synthego introduces CRISPRevolution synthetic sgRNA kit for fast, high-throughput gene editing

Synthego, a leading provider of genome engineering solutions, today announces the world’s first synthetic single guide RNA (sgRNA) CRISPR genome editing kit.

24 Sep 2016

New global map shines light on genetic roots of diseases

A global genetic interaction map is revolutionizing how genes are being studied. A new study, involving University of Minnesota researchers, is no longer looking at genes as loners, but instead as a social network of the body, interacting in groups. The new approach may ultimately change our understanding of the genetic roots of diseases.

23 Sep 2016

Gene editing of hematopoietic stem cells can cure many hereditary and congenital diseases

Recent advances in gene editing technology, which allows for targeted repair of disease-causing mutations, can be applied to hematopoietic stem cells with the potential to cure a variety of hereditary and congenital diseases.

23 Sep 2016

Gene therapy may be viable approach for treating CF lung problems

Two new studies from the University of Iowa suggest that gene therapy may be a viable approach for treating or preventing lung disease caused by cystic fibrosis.

20 Sep 2016

Researchers identify genetic switch that may be potential target for Alzheimer's disease

A team at the MRC Clinical Sciences Centre, based at Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer's Disease.

20 Sep 2016

Researchers identify new gene for type 2 diabetes at well-established genomic location

Gene researchers have used sophisticated scientific tools to reveal a new gene for type 2 diabetes at a well-established genomic location.

31 Aug 2016

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

30 Aug 2016

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of mankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says UC Santa Barbara neuroscientist Kenneth S. Kosik.

27 Aug 2016

Nobel laureate-led study uses new technology to watch interaction between telomerase and telomeres

As the rope of a chromosomes replicates, it frays at the ends. No problem: A chromosome's ends have extra twine so that fraying doesn't reach into the body of the rope where the important information resides.

19 Aug 2016

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure.

18 Aug 2016

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.

18 Aug 2016

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients.

16 Aug 2016

New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

Johns Hopkins researchers say they have identified a new disease gene that, when mutated, appears to increase the risk in a small number of people of developing emphysema and a lung-scarring condition known as pulmonary fibrosis.

10 Aug 2016

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells

A research team headed by investigators at the Icahn School of Medicine at Mount Sinai has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell.

5 Aug 2016

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Many gene mutations that cause neurological disorders have been identified. For example, in a rare neurological disorder such as Huntington’s disease, an autosomal dominant mutation through expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in abnormal protein production.

1 Aug 2016

Pew survey shows Americans worry about using emerging technologies for human enhancement

Many in the general public think scientific and technological innovations bring helpful change to society, but they are more concerned than excited when it comes to the potential use of emerging technologies to make people's minds sharper, their bodies stronger and healthier than ever before, according to a new Pew Research Center survey.

26 Jul 2016

Yale researchers develop new system to simultaneously edit multiple genes

A Yale research team has designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects.

26 Jul 2016

New TSRI study may bring doctors closer to using gene therapies to grow, repair tendons

With the Rio Olympics just weeks away, many are wondering how Jamaican sprinter Usain Bolt will perform.

19 Jul 2016

Study shows how increase in BMI contributes to multiple myeloma growth and progression

In a new study published in Cancer Letters, American University researchers show how, as body mass index increases, so does the growth and spread of the blood cancer multiple myeloma, which accounts for about 10 percent of all blood cancers in patients.

12 Jul 2016

Scientists identify potential drug target that disrupts Zika and similar viruses

Scientists potentially have found a way to disrupt Zika and similar viruses from spreading in the body.

17 Jun 2016