Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Scientists discover master regulator gene for fat storage

We all know that weight gain and weight loss are not as simple as "calories in, calories out," given that countless factors affect body weight.

27 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

Pomegranate's power: Studies show promise in cardiovascular and diabetic health

Researchers reviewed existing data on the bio-modulatory effects of pomegranate (Punica granatum l., PG) polyphenols on metabolic disorders.

24 Nov 2023

Gene therapy could reverse symptoms of rare, hereditary DOOR syndrome

A lot of research has been done over many decades on diseases that are widespread in large parts of the population, such as cancer and heart disease. As a result, treatment methods have improved enormously thanks to long-term research efforts on diseases that affect many people.

23 Nov 2023

Exploring the impact of soy isoflavones in prostate cancer therapy

The cellular mechanisms of soy isoflavones, genistein, daidzein, and equol.

23 Nov 2023

Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

21 Nov 2023

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women's increased risk for the disease and its severity.

21 Nov 2023

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

The study investigates the role of epigenetic changes in GLP1R gene polymorphisms on metabolically healthy obesity (MHO), revealing that apart from genetic variations, DNA methylation significantly influences the occurrence of MHO.

20 Nov 2023

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism -; the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

New insights into how cells maintain their identity over generations

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

16 Nov 2023

AI model predicts patient outcomes across multiple cancer types

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks.

15 Nov 2023

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

RNA-based molecular subtypes modestly improved predictions for pathologic downstaging in muscle-invasive bladder cancer.

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

New approach to CAR T cell therapy may extend treatment effectiveness

CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize and attack cancer cells.

14 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

Traffic emissions disrupt gene expression in human olfactory cells

Exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells, a new study shows.

14 Nov 2023

Gene Expression News and Research

Further Reading

Scientists discover master regulator gene for fat storage

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Pomegranate's power: Studies show promise in cardiovascular and diabetic health

Gene therapy could reverse symptoms of rare, hereditary DOOR syndrome

Exploring the impact of soy isoflavones in prostate cancer therapy

Scientists uncover key to enhancing cancer-killing T cells

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

New insights into how cells maintain their identity over generations

AI model predicts patient outcomes across multiple cancer types

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

New research explores the unique effects of ADHD medications on Drosophila brain cells

New approach to CAR T cell therapy may extend treatment effectiveness

Study reveals mechanisms underlying non-suppressible HIV viremia

Traffic emissions disrupt gene expression in human olfactory cells

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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