Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida.

2 Jul 2014

Outpatient hysteroscopy before IVF doesn't seem to improve IVF results

A large multicentre trial seems finally to have resolved one of IVF's long-running controversies - whether the outlook for women with a poor IVF record can be improved by routine hysteroscopy performed before further IVF treatment.

30 Jun 2014

Researchers find way to diagnose aggressiveness of oral cancer

Studying mouth cancer in mice, researchers have found a way to predict the aggressiveness of similar tumors in people, an early step toward a diagnostic test that could guide treatment, according to researchers at Washington University School of Medicine in St. Louis.

28 Jun 2014

UCSB researchers explore genetic underpinnings of nerve-cell spacing

The functional organization of the central nervous system depends upon a precise architecture and connectivity of distinct types of neurons.

27 Jun 2014

Administering low doses of thyroid hormone to rats with diabetes prevents deterioration of heart function

Administering low doses of a thyroid hormone to rats with diabetes helps restore hormone levels in their hearts and prevented deterioration of heart function and pathology, according to a new study by NYIT College of Osteopathic Medicine Professor and Biomedical Sciences Chair A. Martin Gerdes.

26 Jun 2014

Study: Cohesin mutations are common in melanoma and bladder cancer

Massive sequencing of cancer genomes brings to light new genes every day that could be involved in the process of tumour formation.

25 Jun 2014

Frederic Bushman gets Pioneer Award from Human Gene Therapy

Frederic D. Bushman, PhD's (University of Pennsylvania Perelman School of Medicine) early pioneering work in understanding how HIV reproduces by inserting its genetic material into the DNA of a host cell led to key advances in the ability to move pieces of DNA and whole genes between cells.

25 Jun 2014

Colon has safety mechanism to restrict formation and growth of adenomas

Colon cancer development starts with the formation of benign tumours called adenomas. It is estimated that between 30% and 50% of people over 50 will develop one of these tumours.

24 Jun 2014

Investigators discover novel cellular genes by uncovering uncharacterized RNAs that encode proteins

Case Western Reserve School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts.

23 Jun 2014

Research provides unique insight into lncRNAs that regulate lung development

It's a long way from DNA to RNA to protein, and only about two percent of a person's genome is eventually converted into proteins.

19 Jun 2014

DNA sequencing does not reveal the pathogenicity of bacteria

While more and more genomic information is becoming available at a drastically increasing pace, the knowledge we can gain about how microorganisms interact with their surrounding, infect hosts and alter their molecular programs in accordance to changing environmental conditions remains widely not deducible from genomic data alone, the researchers from University of Southern Denmark claim.

19 Jun 2014

GENETICS and G3: Genes|Genomes|Genetics publish special collection on genetics of immunity

Immunity is what stops you dying from a common cold or a tiny pinprick. Differences in resistance or tolerance to disease influence who catches the bug that's going around the office, or which species succumb to the deadly fungus devastating frogs around the world.

18 Jun 2014

Autistic-like behaviors linked with disruption of Adenomatous Polyposis Coli gene

Autistic-like behaviors and decreased cognitive ability may be associated with disruption of the function of the Adenomatous Polyposis Coli (APC) gene.

17 Jun 2014

Rice University scientists apply new theory to learn how and why cells differentiate

How does a stem cell decide what path to take? In a way, it's up to the wisdom of the crowd.

17 Jun 2014

Researchers explain possibility of using biomarkers in children with JIA to predict status of disease

Data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) demonstrate the possibility of using biomarkers (developed from whole blood gene expression profiles) in children with juvenile idiopathic arthritis (JIA) to predict the status of their disease at 12 months.

13 Jun 2014

Tufts researchers gain new insight into protein associated with bipolar disorder

Researchers from Tufts have gained new insight into a protein associated with bipolar disorder. The study, published in the June 3 issue of Science Signaling, reveals that calcium channels in resting neurons activate the breakdown of Sp4, which belongs to a class of proteins called transcription factors that regulate gene expression.

12 Jun 2014

African-American women at increased risk for deadlier breast cancers, study finds

A research study led by cancer specialists at MedStar Washington Hospital Center found that African-American women frequently present with biologically less favorable subtypes of breast cancer.

10 Jun 2014

New findings on cellular signaling offer potential implications ranging from agriculture to cancer research

A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals about prevailing conditions, a capability that is essential for cells to survive in a fluctuating environment.

9 Jun 2014

Research finding paves way for targeted approaches to treating cancer patients

Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed - specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong.

9 Jun 2014

Researchers uncover several gene networks with potentially important roles in autism

A large new analysis of DNA from thousands of patients has uncovered several underlying gene networks with potentially important roles in autism.

9 Jun 2014

Gene Expression News and Research

Further Reading

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

Outpatient hysteroscopy before IVF doesn't seem to improve IVF results

Researchers find way to diagnose aggressiveness of oral cancer

UCSB researchers explore genetic underpinnings of nerve-cell spacing

Administering low doses of thyroid hormone to rats with diabetes prevents deterioration of heart function

Study: Cohesin mutations are common in melanoma and bladder cancer

Frederic Bushman gets Pioneer Award from Human Gene Therapy

Colon has safety mechanism to restrict formation and growth of adenomas

Investigators discover novel cellular genes by uncovering uncharacterized RNAs that encode proteins

Research provides unique insight into lncRNAs that regulate lung development

DNA sequencing does not reveal the pathogenicity of bacteria

GENETICS and G3: Genes|Genomes|Genetics publish special collection on genetics of immunity

Autistic-like behaviors linked with disruption of Adenomatous Polyposis Coli gene

Rice University scientists apply new theory to learn how and why cells differentiate

Researchers explain possibility of using biomarkers in children with JIA to predict status of disease

Tufts researchers gain new insight into protein associated with bipolar disorder

African-American women at increased risk for deadlier breast cancers, study finds

New findings on cellular signaling offer potential implications ranging from agriculture to cancer research

Research finding paves way for targeted approaches to treating cancer patients

Researchers uncover several gene networks with potentially important roles in autism

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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