Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Gene networks may offer attractive targets for developing new autism drugs

A large new analysis of DNA from thousands of patients has uncovered several underlying gene networks with potentially important roles in autism.

6 Jun 2014

Endocrine Society announces winners of Early Investigators Awards and FLARE Internship Awards

The Endocrine Society is pleased to announce the recipients of the 2014 Early Investigators Awards and the Future Leaders Advancing Research in Endocrinology Internship Awards.

6 Jun 2014

Scientists identify new way to reactivate latent HIV

A team of scientists at the Gladstone Institutes has identified a new way to make latent HIV reveal itself, which could help overcome one of the biggest obstacles to finding a cure for HIV infection.

6 Jun 2014

Tolero Pharmaceuticals reports positive interim results from alvocidib Phase 2 trial for AML treatment

Tolero Pharmaceuticals, Inc., a late clinical-stage biopharmaceutical company developing treatments for oncology and blood disorders, reported positive interim results from an ongoing, randomized Phase 2 clinical trial of its lead drug candidate, alvocidib, in combination with cytarabine plus mitoxantrone for previously untreated acute myeloid leukemia (AML) patients.

6 Jun 2014

New study redefines gene responses to external stimulus

An international team led by scientists at the University of Turku in Finland studied thermally-adapted fish populations to discover that the more biological functions a gene has, the less it responds to environmental change. "In addition to having important implications for climate change adaptation, these findings could radically change the way we study gene responses to any external stimulus like for example to drug treatments", the authors suggest.

5 Jun 2014

Interaction of stress and taste systems could help explain stress-related eating

According to new research from the Monell Center, receptors for stress-activated hormones have been localized in oral taste cells responsible for detection of sweet, umami, and bitter. The findings suggest that these hormones, known as glucocorticoids, may act directly on taste receptor cells under conditions of stress to affect how these cells respond to sugars and certain other taste stimuli.

4 Jun 2014

Scientists design search engine to identify functionally linked genes

Our bodies are as vast as oceans and space, composed of a dizzying number of different types of cells. Exploration reaches far, yet the genes that make each cell and tissue unique have remained largely obscure.

4 Jun 2014

Ovarian cancer patients with molecular subtypes benefit from bevacizumab

Molecular sequencing could identify ovarian cancer patients who are most likely to benefit from treatment with bevacizumab (Avastin), a Mayo Clinic-led study has found.

2 Jun 2014

Pivotal clinical validation study of Myriad myPath Melanoma test presented at ASCO 2014

Myriad Genetics, Inc. today presented results from a pivotal clinical validation study of the Myriad myPath- Melanoma test at the 2014 American Society of Clinical Oncology annual meeting in Chicago, Ill.

2 Jun 2014

Particular genetic variation in humans linked with blond hair

A single-letter change in the genetic code is enough to generate blond hair in humans, in dramatic contrast to our dark-haired ancestors.

2 Jun 2014

New data highlights molecular profiling in guiding treatment of patients with gynecologic malignancies

Caris Life Sciences®, a leading biosciences company focused on fulfilling the promise of precision medicine, announced today the presentation of clinical data from studies demonstrating the potential utility of comprehensive molecular profiling in guiding treatment of patients with gynecologic malignancies, including breast cancers and ovarian cancer.

31 May 2014

Gene regulation responsible for normal breast tissue may also play role in cancer development

About one in eight women in the United States will contract breast cancer in her lifetime. Now new research from Tel Aviv University-affiliated researchers, in collaboration with Johns Hopkins University, has provided another tool to help women, clinicians, and scientists searching for a cure to the one of the most widespread yet incurable diseases on the planet.

30 May 2014

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile - based on a simple blood test - may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.

30 May 2014

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

The overall number and nature of mutations—rather than the presence of any single mutation—influences an individual's risk of developing schizophrenia, as well as its severity, according to a discovery by Columbia University Medical Center researchers published in the latest issue of Neuron.

29 May 2014

Polyplus-transfection introduces FectoPRO transfection reagent

Polyplus-transfection SA, a privately-held company specializing in the development of innovative solutions for transfection, today announces the launch of FectoPRO, the latest optimised transfection reagent in their product portfolio. FectoPRO has been designed for high yields in medium and large-scale production of proteins and antibodies in mammalian cells.

28 May 2014

Gene Expression News and Research

Further Reading

Gene networks may offer attractive targets for developing new autism drugs

Endocrine Society announces winners of Early Investigators Awards and FLARE Internship Awards

Scientists identify new way to reactivate latent HIV

Tolero Pharmaceuticals reports positive interim results from alvocidib Phase 2 trial for AML treatment

New study redefines gene responses to external stimulus

Interaction of stress and taste systems could help explain stress-related eating

Scientists design search engine to identify functionally linked genes

Ovarian cancer patients with molecular subtypes benefit from bevacizumab

Pivotal clinical validation study of Myriad myPath Melanoma test presented at ASCO 2014

Particular genetic variation in humans linked with blond hair

New data highlights molecular profiling in guiding treatment of patients with gynecologic malignancies

Gene regulation responsible for normal breast tissue may also play role in cancer development

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

Polyplus-transfection introduces FectoPRO transfection reagent

Researchers discover signaling pathway in cancer cells that invades nearby tissues

New laser method provides a better understanding on how genes are controlled, regulated

Space Station science: Microgravity on human thyroid carcinoma cells

Chronic bystander viral impairs development of memory T cells

Researchers test genomic sequencing for women with triple negative breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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