Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Identical twins lose some fundamental similarities as they grow older

...a new study reports. They may start to look and act less alike. The changes could leave one twin susceptible to diseases like cancer, while the other twin remains healthy.

11 Jul 2005

Functional analysis of human hematopoietic stem cell gene expression using zebrafish

What do you get when you mix RNA chips and zebrafish? A new two-stage method for studying human gene expression differs in human stem cells and progenitor cells, according to a new article in the open access journal PLoS Biology.

6 Jul 2005

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood.

30 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

Oregon Health & Science University researchers have measured genetic changes reflecting a drop in the body's ability to suppress inflammatory cells that attack nerve fibers and promote progression of multiple sclerosis.

27 Jun 2005

Study challenges understanding of how messenger RNAs are translated into proteins

Our understanding of how messenger RNAs are translated into proteins is challenged by a new study published in the Open Access journal Journal of Biology.

27 Jun 2005

Researchers use PET/CT for molecular imaging of the heart

For the first time, researchers used positron emission tomography (PET)/computed tomography (CT) for imaging the subcellar function of the heart - from its subcellular function to its morphologic appearance. The results of the study were reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Women who have a special genetic profile can conceive spontaneously after the age of 45 years

Dr. Neri Laufer, from the Hadassah University Hospital, Jerusalem, Israel, told the conference that his team's work to identify a specific gene expression profile linked to later fertility would help understanding of the ageing process, as well as enabling the development of better treatments for infertility in older patients.

20 Jun 2005

Scientists have tracked down the biological trigger that gives rise to Van Buchem disease

...a hereditary, disfiguring bone disorder that can cause blindness and deafness. The findings provide insight into long-range gene regulation and could lead to new treatments for osteoporosis and other crippling bone disorders.

16 Jun 2005

Jumping genes help detemine uniqueness of individual brains

Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells.

15 Jun 2005

First clues as to why stem cells ignore stop signs in the cell cycle

Everyone knows that stem cells are controversial. Many people know that stem cells can grow into virtually any cell type found in the body, from a red blood cell to a muscle cell to a brain cell. But no one really knows why stem cells continue to divide and renew themselves long after the point where other cells stop dividing.

10 Jun 2005

DNA discovery may help explain disorders such as autism

Researchers have made a discovery that may in future help to explain many aspects of human social behavior and disorders such as autism.

10 Jun 2005

Variations in genetic code affect social behavior

Why are some people shy while others are outgoing? A study in the current issue of Science demonstrates for the first time that social behavior may be shaped by differences in the length of seemingly non-functional DNA, sometimes referred to as junk DNA.

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Scientists at Lawrence Livermore National Laboratory (LLNL) and the Linnaeus Centre for Bioinformatics (LCB) at Uppsala University in Sweden have developed a new bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity.

8 Jun 2005

Gene therapy for arthritis is both feasible and safe

Gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis.

6 Jun 2005

Researchers successfully image delivery and gene expression of DNA nanoparticles into lungs of CF mice

Researchers at the American Society of Gene Therapy Meeting in St. Louis announced that by using imaging technologies, they are able to successfully trace the delivery of DNA nanoparticles and the extent of gene transfer in the lungs of cystic fibrosis (CF) animals.

6 Jun 2005

Computer simulation helps understand DNA transcription process

New York University chemists have employed a computer simulation whose results have enhanced scientific understanding of the DNA transcription process. The study, funded by the National Institutes of Health, appears in the June 7 issue of the Proceedings of the National Academy of Sciences.

5 Jun 2005

Technology for analyzing gene expression must be standardized

Technology for analyzing gene expression must be standardized among laboratories and across platforms around the world to support this age of human genome exploration, an Oregon Health & Science University researcher says.

29 May 2005

Protein, called "eed," crucial to the regulation of genes in embryonic stem cells

New research from University of North Carolina at Chapel Hill shows how a protein may be crucial to the regulation of genes in embryonic stem cells.

26 May 2005

Gene Expression News and Research

Further Reading

Identical twins lose some fundamental similarities as they grow older

Functional analysis of human hematopoietic stem cell gene expression using zebrafish

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Technique called phylogenetic footprinting reveals new gene regulation system

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

Study challenges understanding of how messenger RNAs are translated into proteins

Researchers use PET/CT for molecular imaging of the heart

Women who have a special genetic profile can conceive spontaneously after the age of 45 years

Scientists have tracked down the biological trigger that gives rise to Van Buchem disease

Jumping genes help detemine uniqueness of individual brains

First clues as to why stem cells ignore stop signs in the cell cycle

DNA discovery may help explain disorders such as autism

Variations in genetic code affect social behavior

New study shows tiny RNAs intimately associated with cancer

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Gene therapy for arthritis is both feasible and safe

Researchers successfully image delivery and gene expression of DNA nanoparticles into lungs of CF mice

Computer simulation helps understand DNA transcription process

Technology for analyzing gene expression must be standardized

Protein, called "eed," crucial to the regulation of genes in embryonic stem cells

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Expanding research and clinical options for children with cancer

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