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Accelovance opens new office in Research Triangle Park, North Carolina

Accelovance, a therapeutically focused clinical research organization (CRO), announced today the opening of a new office in Research Triangle Park (RTP), North Carolina.

20 Feb 2014

Mixed state specifier in DSM-5 overlooks the core features

The replacement of “mixed episodes” with “mixed features” in DSM-5 in order to counter a lack of specificity overlooks two of the core features of mixed states, suggests research published in the Journal of Affective Disorders.

19 Feb 2014

Infection contributes to higher risk of stroke death among blacks

Infection is a stronger trigger of stroke death in African- Americans than in whites, a University of Michigan study shows.

9 Feb 2014

Researcher finds 42% of U.S. hospitals use some type of "telehealth" approach

In the first national look at how broadly web-based technologies are being used to provide health care, a University of Michigan researcher has found that 42 percent of U.S. hospitals use some type of "telehealth" approach.

5 Feb 2014

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Patients with diabetes are at increased risk of microvascular complications, which develop when the body's small blood vessels become diseased. One of the most common problems results when wounds fail to heal properly, which can lead to ulcers, chronic infections, and in the most serious cases, limb amputations.

5 Feb 2014

Sleep recovery good following mild traumatic brain injury

Recovery from sleep disturbance following mild traumatic brain injury occurs more rapidly than depression and anxiety recovery, study findings indicate.

3 Feb 2014

Simple hypomania checklist detects bipolar II disorder

A 15-item hypomania checklist has shown potential for differentiating bipolar disorder, particularly type II, from major depressive disorder.

30 Jan 2014

Acute to chronic insomnia transition warns of depression risk

In patients with acute insomnia, long periods of light sleep may be the key driver to chronic insomnia and depression, research suggests.

27 Jan 2014

Nearly half of hospitalized American adults age 65 require decision-making assistance

Nearly half of hospitalized American adults age 65 and older require decision-making assistance from family members or other surrogates because the patient is too impaired to make decisions independently, according to a new study from the Regenstrief Institute and the Indiana University Center for Aging Research.

23 Jan 2014

Outcome good for patients with dual alcohol use and affective disorders

Alcohol use disorders in patients with depression or bipolar disorder can be successfully treated with intervention and follow-up, say researchers.

22 Jan 2014

Study sheds light on the biological underpinnings of obesity

A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study, published in the January 8 issue of the Journal of Neuroscience, reveals how a protein in the brain helps regulate food intake and body weight. The findings reveal a potential new avenue for the treatment of obesity and may help explain why medications that are prescribed for epilepsy and other conditions that interfere with this protein, such as gabapentin and pregabalin, can cause weight gain.

7 Jan 2014

Quality of life considerations are key when patients consider bariatric surgery

While weight loss surgery offers one of the best opportunities to improve health and reduce obesity related illnesses, the nearly 100,000 Americans who undergo bariatric surgery each year represent only a small fraction of people who are medically eligible for the procedure. Among those who have surgery, Caucasian Americans are twice as likely as African Americans to have weight loss surgery. On the surface, the data appear to signal racial disparity, but when researchers at Beth Israel Deaconess Medical Center dug deeper to ask why this variation exists, the answer was more complicated.

7 Jan 2014

Food labeling, product placement intervention can promote healthy choices

The use of color-coded "traffic light" food labels and changes in the way popular items are displayed appear to have produced a long-term increase in the choice of more healthful food items among customers in a large hospital cafeteria. A Massachusetts General Hospital team reports in the American Journal of Preventive Medicine that the previously reported changes in the proportions of more and less healthy foods purchased in the months after their program began have persisted up to two years after the labeling intervention was introduced.

7 Jan 2014

FDA extends PDUFA Priority Review action date for UC indication of Takeda's vedolizumab

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., today announced that the United States Food & Drug Administration has extended the Prescription Drug User Fee Act Priority Review action date for the ulcerative colitis indication of Takeda's investigational biologic, vedolizumab.

24 Dec 2013

Research roundup: ACA 'can survive' low enrollment; rural/urban differences in O.B. Care; teaching residents cost consciousness

The Health Reform Monitoring Survey (HRMS) was launched in 2013 as a mechanism to obtain timely information on the Affordable Care Act (ACA) ... HRMS data from summer 2013 show that more than 60 percent of those targeted by the health insurance exchanges struggle with understanding key health insurance concepts.

23 Dec 2013

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Takeda Pharmaceutical Company Limited and Natrogen Therapeutics International, Inc. jointly announced today an agreement whereby Takeda will acquire an exclusive license to develop Natrogen's Natura-alpha compound as well as an option to acquire Natrogen. Natura-alpha is a synthetic small molecule oral compound that is believed to inhibit pro-inflammatory cytokine expression, which may help to reduce gastrointestinal inflammation. Natura-alpha is currently in Phase 2 development for the treatment of ulcerative colitis.

20 Dec 2013

Takeda expands commercial platform in Israel

Takeda Pharmaceuticals International GmbH today announced further expansion of its commercial platform with the establishment of its wholly-owned subsidiary in Israel. Together with Algeria, Ecuador, Peru, Singapore and Vietnam, Israel is the sixth sales entity Takeda has opened this year to reinforce its platform in growth markets.

18 Dec 2013

Researchers identify first biomarker that appears to be associated with duration of delirium

Researchers from the Regenstrief Institute and the Indiana University Center for Aging Research have identified the first biomarker that appears to be linked to the duration of delirium.

16 Dec 2013

Brazilian study provides evidence to support effectiveness of Tecta in erosive GERD

Takeda Pharmaceuticals International GmbH announced today results showing pantoprazole magnesium 40 mg (Tecta) was as effective as esomeprazole 40 mg for achieving complete remission (defined as combined endoscopic healing and symptomatic relief) and the mucosal healing rate was high, whilst providing significantly higher symptom relief after 8 weeks.

13 Dec 2013

FDA advisory committee backs Takeda's vedolizumab for treatment of ulcerative colitis, Crohn's disease

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., today announced that a joint panel of members from the Gastrointestinal Drugs and Drug Safety and Risk Management Advisory Committees of the United States Food and Drug Administration voted to recommend approval of Takeda's vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis and Crohn's disease.

9 Dec 2013