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Epigentek develops new approach for identification of "sixth DNA base" 5-hmC

Research experts in the epigenetic field from Epigentek have developed a new, breakthrough approach for the identification of the "sixth DNA base," 5-hydroxymethylcytosine (5-hmC). This technology is based on a high throughput, strip-well format and is also incorporated into the first commercially available product, the MethylFlash(TM) Hydroxymethylated DNA Quantification Kit, for rapidly quantifying hydroxymethylated DNA.

30 Jun 2010

ERC awards VIB-K.U.Leuven scientists 3 million euros in research grants

VIB landed two research grants worth 1.5 million euros each. The prestigious grants are courtesy of the European Research Council (ERC) and are aimed at giving talented young scientists the opportunity to develop their own research team. The honor fell to Adrian Liston and Patrik Verstreken, both recently transferred to VIB-K.U.Leuven from abroad.

30 Jun 2010

New hope for patients with drug-resistant depression

New research shows that a unique strain of laboratory mice characterized at Penn State University has behavioral, hormonal, and neurochemical characteristics that are similar to those of human patients with drug-resistant forms of depression.

30 Jun 2010

Mammalian embryo use different strategies to suppress retroviral infection: Study

Some viruses insert themselves into the host's DNA during infection in a process called retroviral integration, causing several diseases, including AIDS and cancer, notes a Texas A&M researcher who specializes in fetal diseases.

29 Jun 2010

Daiichi Sankyo, Eli Lilly respond to ACCF/AHA clinical alert on FDA's clopidogrel boxed warning

Daiichi Sankyo, Inc. and Eli Lilly and Company appreciate the availability of a "Clinical Alert" from the American College of Cardiology Foundation (ACCF) and American Heart Association (AHA) in response to the FDA's Boxed Warning about Plavix® (clopidogrel), and commend the leading cardiovascular medical societies for providing perspective on the importance of genetic make-up and the variability in response of certain oral anti-platelet (OAP) therapy for patients with acute coronary syndrome (ACS) who are managed with angioplasty and stenting (known as PCI).

29 Jun 2010

Researchers study mechanism of human brain

Because of its intricate organization, figuring out the wiring diagram that explains how the billions of neurons in the brain are connected, and determining how they work together, remains a formidable task.

29 Jun 2010

High-phenolic-content olive oil modifies genes that promote inflammation

Health conscious consumers have long known that virgin olive oil is a good choice when it comes to preparing meals and dipping breads. Now, a team of researchers, including one with the Agricultural Research Service (ARS), has found that phenolic components in olive oil actually modify genes that are involved in the inflammatory response.

29 Jun 2010

Movable sequences of DNA are more common than previously thought

Researchers at the University of Leicester have demonstrated that movable sequences of DNA, which give rise to genetic variability and sometimes cause specific diseases, are far more common than previously thought.

29 Jun 2010

Cancer clues from pregnant lizards

A compound produced by a pregnant lizard may provide important information on the origins and treatment of cancer in humans, according to zoologist Bridget Murphy from the School of Biological Sciences who discovered the protein, which is pivotal to the development of the lizard placenta.

28 Jun 2010

Transposons create genomic instability and are implicated in cancer and other diseases: Research

Transposons, or "jumping genes," make up roughly half of the human genome. Geneticists previously estimated that they replicate and insert themselves into new locations roughly one in every 20 live births.

28 Jun 2010

Researchers identify novel protein complex that regulates genes in fruit flies and mammals

Researchers from the European Molecular Biology Laboratory in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too. Published today in Molecular Cell, their findings explain how another regulatory protein can lead a double life.

28 Jun 2010

Mechanism that regulates stem-cell differentiation in mice may trigger degenerative disease in humans: Research

A mechanism that regulates stem-cell differentiation in mice testes suggests a similar process that may trigger degenerative disease in humans, according to a Penn State College of Agricultural Sciences reproductive physiologist.

28 Jun 2010

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the mother's diet early in pregnancy, according to new findings of an international team led by researchers at UCSF.

28 Jun 2010

Research provides hope and encouragement to people living with lupus

Research presented during the 9th International Lupus Congress held in Vancouver, Canada from June 24-27, 2010 should give hope and encouragement for the future of the treatment and management of lupus to the 1.5 million Americans and 5 million people worldwide living with lupus. In recent years, there have been significant advances made in many areas of lupus research including the development of new treatments, adult stem cell transplantation, genetics, lupus-related cardiovascular disease, and quality of life issues for people with lupus.

25 Jun 2010

Research findings suggest possible diagnostic test for ALS

A team led by a Los Angeles Biomedical Research Institute researcher developed a novel approach to efficiently identify disease relevant genes in human complex neurological disorders and demonstrated the effectiveness of this method by applying it to Amyotrophic Lateral Sclerosis, or Lou Gehrig's Disease, according to a new study reported online in the journal, Human Molecular Genetics.

25 Jun 2010

PARP inhibitors may be effective in men with prostate cancer due to BRCA2 alteration: Researchers

The way prostate cancer develops in men who have an altered 'breast cancer gene' is the same route by which breast cancer develops in women with the same mutation, reveals a study published in PLoS Genetics today (Thursday).

25 Jun 2010

Specific virus can interact with mutation in host's genes to trigger diseases: Scientists

Scientists have shown that a specific virus can interact with a mutation in the host's genes to trigger disease. The observation may help explain why many people with disease risk genes do not actually develop disease.

25 Jun 2010

UH researchers analyze 'wireless connections' in brain to prevent neurological diseases

Many diseases of brain function, such as epilepsy and schizophrenia, are caused by problems in how neurons communicate with each other. A University of Houston researcher and his team are analyzing these commands and connections in an attempt to prevent those diseases.

25 Jun 2010

Gene therapy holds promise in treating cancer, cardiovascular and neurodegenerative diseases

EUREKA project E! 3371 Gene Transfer Agents has made great advances in the development of novel non-viral carriers able to introduce genetic material into the target cells.

25 Jun 2010

Patent application for tumor specific NPC-1C Antigen filed by Neogenix Oncology

Neogenix Oncology announced today that it has filed a patent application with the US Patent and Trade Office for the NPC-1C antigen. This antigen appears to be tumor specific for pancreatic and colorectal tumors.

24 Jun 2010

Genes News and Research

Epigentek develops new approach for identification of "sixth DNA base" 5-hmC

ERC awards VIB-K.U.Leuven scientists 3 million euros in research grants

New hope for patients with drug-resistant depression

Mammalian embryo use different strategies to suppress retroviral infection: Study

Daiichi Sankyo, Eli Lilly respond to ACCF/AHA clinical alert on FDA's clopidogrel boxed warning

Researchers study mechanism of human brain

High-phenolic-content olive oil modifies genes that promote inflammation

Movable sequences of DNA are more common than previously thought

Cancer clues from pregnant lizards

Transposons create genomic instability and are implicated in cancer and other diseases: Research

Researchers identify novel protein complex that regulates genes in fruit flies and mammals

Mechanism that regulates stem-cell differentiation in mice may trigger degenerative disease in humans: Research

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

Research provides hope and encouragement to people living with lupus

Research findings suggest possible diagnostic test for ALS

PARP inhibitors may be effective in men with prostate cancer due to BRCA2 alteration: Researchers

Specific virus can interact with mutation in host's genes to trigger diseases: Scientists

UH researchers analyze 'wireless connections' in brain to prevent neurological diseases

Gene therapy holds promise in treating cancer, cardiovascular and neurodegenerative diseases

Patent application for tumor specific NPC-1C Antigen filed by Neogenix Oncology

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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