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The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

North American arrival of A(H5N1) influenza raises concerns of potential pandemic outbreak

Rapid global expansion of highly pathogenic avian influenza A(H5N1) viruses in 2021, including reassortment with North American strains, highlights the need for proactive measures to combat their spread and mitigate the risk of a potential pandemic originating from these reassortants.

31 May 2023

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study explores the effects of a green-MED diet enriched in polyphenols and reduced in red/processed meat on the methylome and transcriptome levels. It aims to uncover the molecular mechanisms underlying the observed metabolic improvements.

30 May 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Research finds more depressed patients with activated immune systems than previously estimated

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has used an assessment of gene expression involved in the immune response to show that there could be more patients with MDD with activated immune systems than research has previously estimated.

30 May 2023

Genetic change supercharged spread and severity of epizootic H5N1 avian influenza virus

St. Jude Children's Research Hospital scientists discovered how the current epizootic H5N1 avian influenza virus (bird flu) gained new genes and greater virulence as it spread west.

30 May 2023

DNA test results may enhance prevention and treatment of alcohol use disorder

Today's substance use prevention efforts ignore individual genetic risk, but Rutgers research suggests DNA test results may eventually enhance prevention and treatment and improve outcomes.

30 May 2023

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

The low blood oxygen levels of obstructive sleep apnea cause widespread changes in gene activity throughout the day, according to a new study in the open-access journal PLOS Biology by David Smith of Cincinnati Children's Hospital Medical Center, US, and colleagues.

30 May 2023

Study shows impacts of ASO-based MALAT1-inhibition on MAPK-pathway gene regulation in melanoma

A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, "Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment."

30 May 2023

Alternative gene splicing can impact the risk for alcohol use disorder

Researchers at Indiana University School of Medicine have discovered alternative gene splicing, which occurs during gene expression, can impact a person's risk of alcohol use disorder (AUD).

30 May 2023

Mutated gene protects the kidney from hypertension-induced damage

A mutation that causes severe hypertension also protects the kidneys from being damaged, reports a team led by Enno Klußmann of the Max Delbrück Center and the DZHK in "Kidney International".

30 May 2023

Researchers find oldest evidence of the plague in Britain to date

Researchers at the Francis Crick Institute have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague – the oldest evidence of the plague in Britain to date, reported in a paper published today in Nature Communications.

30 May 2023

Mammograms at 40? Breast cancer screening guidelines spark fresh debate

While physicians mostly applauded a government-appointed panel's recommendation that women get routine mammography screening for breast cancer starting at age 40, down from 50, not everyone approves.

30 May 2023

Mental health profoundly impacts inflammatory responses in the body

Study uncovered mechanisms by which psychological stress affects bowel inflammation.

30 May 2023

Battle against superbugs: E. coli resistance in UTIs shows slight decline

Research finds that the prevalence of antimicrobial resistance (AMR) of uropathogenic Escherichia coli (UPEC) from outpatient uncomplicated UTIs at KPSC has slightly decreased between 2016 and 2021, both for in-person and virtual settings, although the magnitude of the decrease was mostly small. Resistance to penicillins, fluoroquinolones, and TMP-SMX was common.

30 May 2023

Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

Study identifies new genes associated with heart attack risk largely affecting younger women

Research led by the National Institute for Health and Care Research Leicester Biomedical Research Centre (BRC) and Universite Paris Cite, and supported by worldwide partners in Canada, the USA and Australia, has identified new genes that are associated with an increased risk of a type of heart attack primarily affecting young to middle-aged women.

29 May 2023

Illinois Tech selected as enrollment site for NIH's landmark initiative to advance nutrition research

Illinois Institute of Technology is one of 14 institutions chosen as an enrollment site for the National Institute of Health's landmark initiative to advance nutrition research.

26 May 2023

Fission yeast study sheds new light on gross chromosomal rearrangement

When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body's genetic code, DNA, which is stored in structures known as chromosomes, can bring about mutations in the body.

26 May 2023

Two bacteria that co-occur with C. difficile as emerging potential threats in planetary health

A new study published in the peer-reviewed OMICS: A Journal of Integrative Biology identified genes for virulence and antimicrobial resistance in two bacteria that co-occur with C. difficile, suggesting these pathogens as emerging potential threats in planetary health.

26 May 2023

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Genes News and Research

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

North American arrival of A(H5N1) influenza raises concerns of potential pandemic outbreak

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Research finds more depressed patients with activated immune systems than previously estimated

Genetic change supercharged spread and severity of epizootic H5N1 avian influenza virus

DNA test results may enhance prevention and treatment of alcohol use disorder

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

Study shows impacts of ASO-based MALAT1-inhibition on MAPK-pathway gene regulation in melanoma

Alternative gene splicing can impact the risk for alcohol use disorder

Mutated gene protects the kidney from hypertension-induced damage

Researchers find oldest evidence of the plague in Britain to date

Mammograms at 40? Breast cancer screening guidelines spark fresh debate

Mental health profoundly impacts inflammatory responses in the body

Battle against superbugs: E. coli resistance in UTIs shows slight decline

Obesity strikes below the belt: Study reveals link between obesity and male infertility

Study identifies new genes associated with heart attack risk largely affecting younger women

Illinois Tech selected as enrollment site for NIH's landmark initiative to advance nutrition research

Fission yeast study sheds new light on gross chromosomal rearrangement

Two bacteria that co-occur with C. difficile as emerging potential threats in planetary health

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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