Genes News and Research

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Discovery of gene that could help develop HIV/AIDS vaccine

In an article published in the journal Science on Thursday, researchers announced that they have discovered a gene, called Apobec3, that might help in the development of an HIV/AIDS vaccine, Reuters Health reports.

9 Sep 2008

Physical activity can blunt the effect of obesity genes

People who are concerned that they may have a genetic susceptibility for obesity will find some relief from new research conducted in the U.S.

9 Sep 2008

Egg secretions from a worm may be useful in gene therapy

Egg secretions from a worm that causes a deadly human disease may prove useful in gene therapy, according to research presented at the British Pharmaceutical Conference (BPC) in Manchester.

8 Sep 2008

The Cancer Genome Atlas reports first results

The Cancer Genome Atlas (TCGA) has reported results from its first comprehensive study which focused on the deadly brain cancer glioblastoma.

8 Sep 2008

Framing the concept of a gene

Even scientists define 'a gene' in different ways, so it comes as little surprise that the media also have various ways of framing the concept of a gene, according to a new study appearing in the October 2008 issue of EMBO reports.

4 Sep 2008

Link found between Apobec3 gene and neutralizing antibody response to retrovirus

Scientists have uncovered new evidence that strengthens the link between a host-cell gene called Apobec3 and the production of neutralizing antibodies to retroviruses. Published in the Sept. 5 issue of Science, the finding adds a new dimension to the set of possible explanations for why most people who are infected with HIV do not make neutralizing antibodies that effectively fight the virus.

4 Sep 2008

FDA 'fast track' granted to BioMS Medical for lead drug, dirucotide for the treatment of multiple sclerosis

BioMS Medical Corp has announced that the Food and Drug Administration (FDA) of the United States has granted fast track designation for the Company's lead drug, dirucotide (MBP8298), for the treatment of secondary progressive MS (SPMS). Dirucotide (MBP8298) is currently being evaluated in a U.S. pivotal phase III trial, named MAESTRO-03, at 68 sites with approximately 510 patients.

4 Sep 2008

Why bypass surgery helps in diabetes

To manage obesity, various different surgical procedures can be performed on the stomach, including so-called bypass surgery in which, as well as reducing the size of the stomach, a bypass is created to send food directly into the distal gut (which, before the operation, is far from the stomach).

3 Sep 2008

Researchers find genetic proof on how osteoarthritis destroys cartilage

A team of orthopaedic researchers has found definitive, genetic proof of how the most common form of arthritis destroys joint cartilage in nearly 21 million aging Americans, according to a study published online Sept. 2 in the Journal of Bone and Mineral Research. The findings serve as an important foundation for the design of new treatments for osteoarthritis (OA), researchers said.

2 Sep 2008

Human herpes virus 6 weaves itself into the DNA transferred from parents to babies

Parents expect to pass on their eye or hair color, their knobby knees or their big feet to their children through their genes. But they don't expect to pass on viruses through those same genes.

2 Sep 2008

Discovery of novel candidate gene for inflammatory bowel diseases

A study of Crohn's disease and ulcerative colitis in children has identified a gene that influences whether children get these diseases early in life, and points to a potential new target for treatment.

2 Sep 2008

Nature inspires new highly specific drugs and organic products

The best place to seek novel compounds for pharmaceutical drugs, alternative energy sources, and a host of industrial applications, is within natural systems that have evolved over millions of years.

2 Sep 2008

Issues on cholesterol: diet, statins and genetics

Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease (CAD). An example of strong genetic predisposition is the disorder: familial hypercholesterolemia, where a single gene defect (the low density lipoprotein receptor) contributes to most of the familial expression of CAD.

1 Sep 2008

New genetic link to inflammatory bowel diseases discovered

A study which entailed scientists trawling through the genetic code of thousands of people, has revealed two new genes involved in childhood inflammatory bowel disease, a painful condition that includes Crohn's disease and ulcerative colitis (UC).

1 Sep 2008

Genetic link discovered to common form of leukaemia

Researchers in the UK have discovered a genetic link to a common form of leukaemia.

1 Sep 2008

Discovery of new genes for inflammatory bowel disease in children

Researchers have discovered two new genes that increase the risk of developing inflammatory bowel disease (IBD) in childhood.

31 Aug 2008

Low levels of 'brain derived neurotrophic factor' may lead to obesity

A brain chemical that plays a role in long term memory also appears to be involved in regulating how much people eat and their likelihood of becoming obese, according to a National Institutes of Health study of a rare genetic condition.

28 Aug 2008

Transformation of ordinary cells into insulin-makers improves symptoms of diabetes

Scientists in the U.S. have successfully transformed ordinary cells into insulin-producing cells in a living mouse and thereby improved the symptoms of diabetes.

28 Aug 2008

Berries show to have a genome-wide effect on the expression of genes involved in cancer development

New research strongly suggests that a mix of preventative agents, such as those found in concentrated black raspberries, may more effectively inhibit cancer development than single agents aimed at shutting down a particular gene.

27 Aug 2008

Discovery of genes that may predispose to anxiety disorders

Finnish scientists have identified genes that may predispose to anxiety disorders. Research conducted under the supervision of Academy Research Fellow Iiris Hovatta have focused on genes that influence human behaviour, and some of the studied genes show a statistical association with specific anxiety disorders. The work is carried out as part of the Academy of Finland Research Programme on Neuroscience (NEURO).

27 Aug 2008