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Transformation of ordinary cells into insulin-makers improves symptoms of diabetes

Scientists in the U.S. have successfully transformed ordinary cells into insulin-producing cells in a living mouse and thereby improved the symptoms of diabetes.

28 Aug 2008

Berries show to have a genome-wide effect on the expression of genes involved in cancer development

New research strongly suggests that a mix of preventative agents, such as those found in concentrated black raspberries, may more effectively inhibit cancer development than single agents aimed at shutting down a particular gene.

27 Aug 2008

Discovery of genes that may predispose to anxiety disorders

Finnish scientists have identified genes that may predispose to anxiety disorders. Research conducted under the supervision of Academy Research Fellow Iiris Hovatta have focused on genes that influence human behaviour, and some of the studied genes show a statistical association with specific anxiety disorders. The work is carried out as part of the Academy of Finland Research Programme on Neuroscience (NEURO).

27 Aug 2008

FDA clears non-invasive test to help manage heart transplant patients

The U.S. Food and Drug Administration has announced it has cleared for marketing a non-invasive test that uses molecular expression techniques to assist doctors in managing heart transplant patients post-surgery for potential organ rejection.

27 Aug 2008

UT Southwestern discovery may lead to new drug-abuse treatments

Increased connections among brain cells caused by excessive drug use may represent the body's defense mechanism to combat addiction and related behaviors, scientists at UT Southwestern Medical Center have found.

27 Aug 2008

Alabama board approves plan to charge state employees for obesity, health problems

The Alabama State Employees' Insurance Board last week approved a plan that will require state employees who are obese or have health problems to make progress to address those issues or pay a monthly charge for health insurance, the AP/Philadelphia Inquirer reports.

26 Aug 2008

Early trigger for type-1 diabetes found in mice

Scientists at the Stanford University School of Medicine are shedding light on how type-1 diabetes begins.

26 Aug 2008

Study reveals how blood flow force protects against atherosclerosis

Machines on cell surfaces, mechanical and lifeless as bed springs, protect blood vessels by responding to blood flow force, according to research published today in the Journal of Cell Biology. By sensing and reacting to force, such machines interfere with inflammatory pathways central to atherosclerosis, the cause of clogged arteries that lead to heart attack and stroke, the authors said. The next set of studies, already underway, seeks to "tweak" the process with the goal of designing a new class of therapies.

25 Aug 2008

Scientists uncover molecule that keeps pathogens like salmonella in check

Scientists at UT Southwestern Medical Center have found a potential new way to stop the bacteria that cause gastroenteritis, tularemia and severe diarrhea from making people sick.

21 Aug 2008

Brown fat points to new ways to fight obesity

A surprise discovery -- that calorie-burning brown fat can be produced experimentally from muscle precursor cells in mice -- raises the prospect of new ways to fight obesity and overweight, say scientists from Dana-Farber Cancer Institute.

20 Aug 2008

New research suggests inherited diabetes may play a role in rising rates

A new study in the September issue of the Journal of Lipid Research suggests an unusual form of inheritance may have a role in the rising rate of diabetes, especially in children and young adults, in the United States.

20 Aug 2008

Scientists trace evolution of the nerve cell

University of Queensland researchers have traced the origins of one of the most important steps in animal evolution - the development of nerves.

20 Aug 2008

Attacking heart failure in the young

Pediatric cardiology experts from around the world will gather at the Indiana University School of Medicine for the inaugural Riley Heart Center Symposium on Cardiac Development Sept. 8-9 at Riley Hospital for Children.

19 Aug 2008

Australians have the right to know if they are eating GM food say chefs

A leading Australian nutritionist and top Australian chefs have joined forces with Greenpeace in demands for the comprehensive labelling and testing of genetically modified (GM) food products.

18 Aug 2008

Researchers uncover attack mechanism of illness-inducing bacterium found in shellfish

An infectious ocean-dwelling bacterium found in oysters and other shellfish kills its host's cells by causing them to burst, providing the invader with a nutrient-rich meal, researchers at UT Southwestern Medical Center have found.

18 Aug 2008

Variation in Ankyrin 3 gene shows strong association with bipolar disorder

The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. Researchers supported in part by the National Institute of Mental Health, part of the National Institutes of Health, found an association between the disorder and variation in two genes that make components of channels that manage the flow of the elements into and out of cells, including neurons.

17 Aug 2008

Cancer signatures uncovered

A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. The research, published recently in BioMed Central's open access journal Genome Biology, describes how cancers can be divided into three groups distinguished by disparate developmental signatures.

17 Aug 2008

By amplifying cell death signals, scientists make precancerous cells self-destruct

When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the signals that tell these precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction.

17 Aug 2008

Discovery of major genetic cause of colorectal cancer

About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases.

14 Aug 2008

New model for studying the genetics of Angelman syndrome

A model for studying the genetics of Angelman syndrome, a neurological disorder that causes mental retardation and other symptoms in one out of 15,000 births, has been developed by biologists at The University of Texas at Austin.

14 Aug 2008