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Hydrogen sulfide provides clues to a longer life

Hydrogen sulfide, or H2S, the chemical that gives rotten eggs their sulfurous stench - and the same compound that researchers at Fred Hutchinson Cancer Research Center successfully have used to put mice into a state of reversible metabolic hibernation - has now been shown to significantly increase life span and heat tolerance in the nematode worm, or C. elegans.

4 Dec 2007

Cold Spring Harbor Protocols features innovative methods for embryology research

Two methods that permit scientists to examine critical stages in early embryogenesis are featured in this month's release of Cold Spring Harbor Protocols.

4 Dec 2007

Prolonged exposure to night shift work increases odds of cancer

A study by the World Health Organization has found that night shift work increases the risk of cancer in humans.

3 Dec 2007

New tool for analyzing genetic variations in the inflammation pathways

Scientists have known which genes are linked to inflammation, but now researchers at Wake Forest University Baptist Medical Center have organized this information to develop a powerful tool to aid investigators in studying the genetics of inflammatory diseases.

3 Dec 2007

Boosting an exercise-related gene in the brain works as a powerful anti-depressant in mice

This finding could lead to a new anti-depressant drug target, according to a Yale School of Medicine report in Nature Medicine.

3 Dec 2007

Broccoli shows benefits for epidermolysis bullosa simplex

The compound sulforaphane whose natural precursors are found at high levels in broccoli and other cruciferous vegetables has been hailed for its chemopreventive powers against cancer.

3 Dec 2007

Genomic disorders occur more frequently than previously thought

Research published today in Nature Genetics shows that some rearrangements of the human genome occur more frequently than previously thought.

3 Dec 2007

Discovery of key lupus gene

Wellcome Trust researchers have identified a key gene involved in the disease Lupus, which affects around 50,000 people in the UK, mostly women.

3 Dec 2007

Genetic testing over the net a waste of money say experts

According to a panel of top British scientists people who buy genetic tests from private companies are usually wasting their money.

3 Dec 2007

First map of imprinted genes in human genome

Scientists at Duke University have created the first map of imprinted genes throughout the human genome, and they say a modern-day Rosetta stone – a form of artificial intelligence called machine learning – was the key to their success.

2 Dec 2007

DNA methylation shown to promote development of colon tumors

Damaged or defective genes have long been known to be the cause of some cancers.

2 Dec 2007

Bacteria cheat on their mates for own good

Pursuing our own short term interests by cheating on the rest of the population is not the preserve of the human race.

29 Nov 2007

Sirtris Pharmaceuticals unveils promising, novel SIRT1 activators for treating diseases of aging

Sirtris Pharmaceuticals has announced that findings in the journal Nature demonstrate that Sirtris has developed novel drug candidates that offer a promising, new approach to treating diseases of aging, including Type 2 Diabetes, by targeting SIRT1, a gene that controls the aging process.

29 Nov 2007

New genetic findings on malaria parasite

The malaria parasite has been studied for decades, but surprisingly, little is known about how it behaves in humans to cause disease.

29 Nov 2007

Scientists observe gene activity outside the body

Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer Center in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body.

29 Nov 2007

Genetic selection of target stem cell populations

Human embryonic stem cells can be genetically manipulated to help select out desirable cell types, according to a University of Nottingham study published online in Molecular Therapy.

29 Nov 2007

Genetic differences point to ethnic and racial disparities in colorectal cancer risk

Risk of developing colorectal cancer is known to differ across ethnic and racial groups, and now an analysis of 26 studies, involving over 25,000 participants shows that some of these disparities might be explained by distinct patterns of genetic inheritance.

29 Nov 2007

Aging in mice at the molecular level

Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues.

29 Nov 2007

Scientists adopt fresh approach in quest for new therapies

Scientists are to pool their expertise in human health to pioneer an innovative approach to treating common diseases.

27 Nov 2007

Discovery of key acute myeloid leukemia gene

A gene called N-Myc leads a double life in certain white blood cells, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.

27 Nov 2007