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Researchers develop an algorithm to identify high-risk precancerous lesions on the fallopian tubes

Researchers at the Johns Hopkins Kimmel Cancer Center and the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine have developed an algorithm to identify high-risk precancerous lesions on the fallopian tubes.

14 Mar 2024

Study identifies CDK9's involvement in DNA repair during cell division

Researchers describe a newly-observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth.

14 Mar 2024

Understanding the genetic and cellular impact of smoking

It's no secret that smoking is extremely detrimental to health. Tobacco smoke contains thousands of chemicals, including carcinogens, increasing the risk of cancer, cardiovascular and respiratory diseases.

14 Mar 2024

Gene discovery provides new insight into brain calcification

Brain calcification can cause movement disorders and cognitive impairment. Researchers at the Arnesen Lab at UiB have now identified a gene that provides new insight into how these calcifications occur.

14 Mar 2024

Researchers shed light on cancer cell survival in early hypoxia

Researchers at the Francis Crick Institute have shed light on how cancer cells survive in the first few hours after being cut off from a supply of oxygen.

14 Mar 2024

Living with IBD: What coping strategies are most effective?

The results of a systematic review that explored the impact of different coping strategies for people living with inflammatory bowel disease (IBD).

14 Mar 2024

Innovative super minigene to revolutionize spinal muscular atrophy research

Ravindra Singh has spent years studying a gene that when missing or mutated causes spinal muscular atrophy (SMA), a deadly disease that's among the most common genetic disorders in children.

13 Mar 2024

Targeting a non-encoding stretch of RNA may shrink pediatric brain tumors in mice

Targeting a non-encoding stretch of RNA may help shrink tumors caused by an aggressive type of brain cancer in children, according to new research in mice reported March 8 in Cell Reports by Johns Hopkins Kimmel Cancer Center investigators.

13 Mar 2024

Researchers discover diverse and spatially coordinated cardiac cells involved in heart development

Researchers use a combination of scRNA-seq and multiplexed error-robust fluorescence in situ hybridization to better understand cardiac cell types.

13 Mar 2024

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

12 Mar 2024

T1-spanin breakthrough offers new hope against antibiotic resistance

Given the worldwide prevalence of drug-resistant bacteria, the research fraternity is on the lookout for alternative bactericidal treatment approaches.

12 Mar 2024

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

12 Mar 2024

Groundbreaking study unveils sex-specific genetic influences on blood pressure

Genetic heterogeneity of blood pressure (BP) effects between sexes.

12 Mar 2024

Scientists find answers about cardiovascular diseases by probing the cellular "glue"

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

11 Mar 2024

Researchers explore the role of vitamin A in pathogenesis of psychiatric disorders

A Newcastle research team has been exploring the role of vitamin A in the pathogenesis of psychiatric disorders.

11 Mar 2024

Novel genetic link uncovered in generalized pustular psoriasis

A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team's findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.

9 Mar 2024

Study unravels FOXO1's influence on blood vessel development

The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for tackling age-related disorders.

9 Mar 2024

Study reveals blood markers to predict healthspan and aging trajectories

University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person's biological age -; how fast a person's cells and organs age regardless of their birthdate.

8 Mar 2024

The effects of high maternal folate intake on the health outcomes of offspring

Researchers summarized what is known about the effects of excessive folic acid (FA) supplementation for mothers on children.

8 Mar 2024

Parental obesity linked to higher odds of adult offspring obesity

Individuals have six times the odds of living with obesity in middle age if both their parents lived with obesity at that age, new research to be presented at the European Congress on Obesity (ECO 2024, Venice, 12-15 May), has found. Having one parent living with obesity trebles the odds.

7 Mar 2024