Genes News and Research

RSS

Genetic testing for Parkinson disease, is there a point?

Should we start being genetically tested for Parkinson’s disease (PD)? According to research just published in the December issue of the "journal Movement Disorders" this might be a possibility in the future if you belong to a family affected by G2019S, a genetic mutation responsible for some PD cases.

7 Dec 2005

New type of sulfite reductase

Biswarup Mukhopadhyay and Eric Johnson from the Virginia Bioinformatics Institute at Virginia Tech have discovered a novel enzyme that represents an ancient detoxification system and provides a clue to the development of early metabolism on earth.

7 Dec 2005

Hippocampal myo-inositol and cognitive ability in adults with Down Syndrome

Researchers from the Institute of Psychiatry at King's College London have identified a molecule that could be targeted to treat the cognitive impairment in people with Down syndrome.

7 Dec 2005

MicroRNAs greatly influence the evolution of genes

RNA continues to shed its reputation as DNA's faithful sidekick. Now, researchers in the lab of Whitehead Institute Member David Bartel have found that a class of small RNAs called microRNAs influence the evolution of genes far more widely than previous research had indicated.

7 Dec 2005

Liver plays crucial role in iron metabolism

A new study in the December Cell Metabolism reveals an unexpected connection between a tumor suppressor gene in the liver and the normally careful control over the amount of iron absorbed from the diet.

7 Dec 2005

Humans have ancient genes

Species evolve at very different rates, and the evolutionary line that produced humans seems to be among the slowest.

7 Dec 2005

UK DNA Banking Network

Doctors and scientists nationwide wil for the first time be able to join together over the internet to start the search for genes that underlie a range of chronic diseases.

From The University of Manchester 6 Dec 2005

Fibroblast research could lead to alternatives to implanted electronic pacemakers

In guinea pig experiments, Johns Hopkins scientists fused common connective tissue cells taken from lungs with heart muscle cells to create a safe and effective biological pacemaker whose cells can fire on their own and naturally regulate the muscle's rhythmic beat.

5 Dec 2005

LEDGF protein controls the location of HIV integration in human cells

A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells, according to researchers at the University of Pennsylvania School of Medicine.

5 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Researchers move in on novel therapeutics to inhibit melanoma

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

5 Dec 2005

HRAS mutation analysis in Costello Syndrome

Gene mutations in the HRAS sequence are present in most patients affected with Costello syndrome, according to a new study in the American Journal of Medical Genetics. The mutations occurred de novo in patients, meaning, they were not observed in their parents' genes.

5 Dec 2005

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

Gene is associated with increased risk of precursor of macular degeneration A variant in a gene called Complement Factor H (CFH) appears to contribute to the increased risk of advanced age-related macular degeneration (AMD) largely or entirely through its impact on the development of a precursor of advanced AMD called soft drusen (small yellowish, extracellular deposits of lipid, protein and cellular debris in the back of the eye), according to a multinational team of researchers.

2 Dec 2005

Disruption of normal gene interaction linked to schizophrenia

Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a group of investigators that includes a scientist now at St. Jude Children's Research Hospital.

2 Dec 2005

Researchers identify a gene affecting blood pressure

Research published by University of Leicester researchers in the top journal "Circulation" identifies a gene that affects blood pressure levels in the general population.

30 Nov 2005

Bacterial DNA and IVF contamination risk on New Scientist

Some children conceived by a common method of IVF could be carrying chunks of bacterial DNA in their chromosomes, according to a study in mice. The researchers who conducted the work say that such accidental genetic modification would be very rare, but they argue that fertility doctors should take more precautions to exclude it.

30 Nov 2005

Drug partners in fight against AIDS say measles shot could be the answer!

Major drug company GlaxoSmithKline is hoping to develop an experimental AIDS vaccine by "piggy-backing" on a shot against measles.

29 Nov 2005

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

Most people with a rare type of dementia called primary progressive aphasia (PPA) have a specific combination of prion gene variants, a new study shows.

28 Nov 2005

Breastfeeding may protect children against gluten intolerance

Breastfeeding may protect children against gluten intolerance otherwise known as coeliac disease, suggests research published ahead of print in the Archives of Disease in Childhood.

28 Nov 2005

Exploiting biology's own chemical toolbox...

Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.

28 Nov 2005