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Promising new type of cancer treatment to benefit more patients

More patients than ever stand to benefit from a promising new type of cancer treatment, after scientists compiled a library of molecules that can prime patients’ immune systems to fight a range of cancers including leukaemia, myeloma, lung cancer and skin cancer.

15 Oct 2013

Barcelona to host European Drosophila Research Conference

From 16 to 19 October, more than 700 international scientists will attend the European Drosophila Research Conference, the most important European conference focused on basic and biomedical research that uses the fly fruit, Drosophila melanogaster, as a model system.

15 Oct 2013

Researchers identify genetic variants associated with Barrett's and esophageal cancer

An international consortium co-led by researchers at Fred Hutchinson Cancer Research Center and the QIMR Berghofer Medical Research Institute in Australia has identified four genetic variants associated with an increased risk of esophageal cancer and its precursor, a condition called Barrett's esophagus.

14 Oct 2013

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Bladder cancer represents a serious public health problem in many countries, especially in Spain, where 11,200 new cases are recorded every year, one of the highest rates in the world. The majority of these tumours have a good prognosis -- 70-80% five-year survival after diagnosis -- and they do not infiltrate the bladder muscle at the time of diagnosis -- in around 80% of cases.

14 Oct 2013

Researchers create online database of disease genes that could be targeted with drugs

Researchers at Washington University School of Medicine in St. Louis have created a massive online database that matches thousands of genes linked to cancer and other diseases with drugs that target those genes.

14 Oct 2013

Scientists discover genetic mutation associated with low-risk bladder cancer

An international research team led by scientists from Georgetown Lombardi Comprehensive Cancer Center has discovered a genetic mutation linked to low-risk bladder cancer.

13 Oct 2013

New approach could help identify specific gene mutations linked to increased disease risk

Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off.

13 Oct 2013

PARP inhibitor drugs and chemotherapy can help women with ovarian cancer live longer

Conventional chemotherapy could further extend life in some women with ovarian cancer when used in tandem with a new type of targeted treatment, a new international study shows.

13 Oct 2013

Research findings may lead to new ways to combat cancer

The way cells divide to form new cells - to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning - is controlled in previously unsuspected ways UC San Francisco researchers have discovered.

12 Oct 2013

Researchers discover how Fra-1 protein protects the liver from drug-induced liver damage

Drug abuse and alcohol are some of the most frequent causes of liver damage, particularly in developed countries. Such kind of liver damage can cause irreversible liver failure and even cancer. Researchers from the Spanish National Cancer Research Centre have discovered an important new protective role of the Fra-1 protein, which neutralizes the damage caused by agents, such as the analgesic drug acetaminophen (Paracetamol).

12 Oct 2013

Research findings may lead to potential treatments for inherited diseases

New research from the University of California, Davis, shows that the tiny proportion of a cell's DNA that is located outside the cell nucleus has a disproportionately large effect on a cell's metabolism.

12 Oct 2013

ADAGES III study receives NIH grant to elucidate genetics of glaucoma in African descents

A study led by Robert N. Weinreb, chairman and Distinguished Professor of Ophthalmology at the University of California, San Diego School of Medicine, has received a $6.4 million, 5-year grant from the National Eye Institute, part of the National Institutes of Health, to elucidate the genetics of glaucoma in persons of African descent.

12 Oct 2013

Change in gene expression occurs in patients with "pouchitis" after UC surgery

"Pouchitis" developing after surgery for ulcerative colitis (UC) is associated with changes in gene expression, which increase along with disease severity, reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

11 Oct 2013

HSCI researchers discover on-off switch for gene expression

Harvard Stem Cell Institute researchers have settled a century-old debate over whether occurrence of DNA methylation acts to silence gene expression, or if genes are turned off by other means before they are methylated.

11 Oct 2013

Super-enhancers could play important roles in disease diagnostics and therapeutics

Having recently discovered a set of powerful gene regulators that control cell identity in a few mouse and human cell types, Whitehead Institute scientists are now showing that these regulators-which they named "super-enhancers"-act across a vast array of human cell types and are enriched in mutated regions of the genome that are closely associated with a broad spectrum of diseases.

11 Oct 2013

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

In an unprecedented move, the California Academy of Sciences today will induct two scientists from the Gladstone Institutes', President R. Sanders "Sandy" Williams, MD, and Investigator Katherine Pollard, PhD, as Academy Fellows, bestowing yet another honor on two of San Francisco's most esteemed scientists.

11 Oct 2013

Genetic mutation that protects skin from UV radiation may cause testicular cancer in Caucasian

A Ludwig Cancer Research study published in Cell today identifies a common mutation that dramatically increases the risk for testicular cancer—and describes a likely molecular mechanism by which it exerts that effect.

11 Oct 2013

Researchers identify gene that orchestrates important branching of nerve fibers

Our ability to detect heat, touch, tickling and other sensations depends on our sensory nerves. Now, for the first time, researchers at Albert Einstein College of Medicine of Yeshiva University have identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell.

11 Oct 2013

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

When The Cancer Genome Atlas launched its massively collaborative approach to organ-by-organ genomic analysis of cancers, the brain had both the benefit, and the challenge, of going first.

11 Oct 2013

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Charles J. Sherr, M.D., Ph.D., chair of the St. Jude Children's Research Hospital Department of Tumor Cell Biology and a Howard Hughes Medical Institute Investigator, has been selected to receive the 2013 Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.

10 Oct 2013

Genes News and Research

Promising new type of cancer treatment to benefit more patients

Barcelona to host European Drosophila Research Conference

Researchers identify genetic variants associated with Barrett's and esophageal cancer

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Researchers create online database of disease genes that could be targeted with drugs

Scientists discover genetic mutation associated with low-risk bladder cancer

New approach could help identify specific gene mutations linked to increased disease risk

PARP inhibitor drugs and chemotherapy can help women with ovarian cancer live longer

Research findings may lead to new ways to combat cancer

Researchers discover how Fra-1 protein protects the liver from drug-induced liver damage

Research findings may lead to potential treatments for inherited diseases

ADAGES III study receives NIH grant to elucidate genetics of glaucoma in African descents

Change in gene expression occurs in patients with "pouchitis" after UC surgery

HSCI researchers discover on-off switch for gene expression

Super-enhancers could play important roles in disease diagnostics and therapeutics

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

Genetic mutation that protects skin from UV radiation may cause testicular cancer in Caucasian

Researchers identify gene that orchestrates important branching of nerve fibers

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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