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Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome - a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity - is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep.

26 Jun 2013

PLK1 crucial for proper functioning of cancer cells, researchers reveal

One of the main indicators for determining the activity of a tumour or cancer is cell division. Cancer cells divide more than other types and the genes and molecules involved in the process of division are, often, targets for identifying and treating certain types of cancer.

26 Jun 2013

Study finds PTSD as risk factor for heart disease among Vietnam vets

Male twin Vietnam veterans with post-traumatic stress disorder were more than twice as likely as those without PTSD to develop heart disease during a 13-year period, according to a study supported by the National Institutes of Health.

26 Jun 2013

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives FDA clearance

BioFire Diagnostics, Inc., announced today the FDA clearance of its FilmArray Blood Culture Identification Panel. To date, the 27-target panel is the most comprehensive test to be approved by the FDA.

26 Jun 2013

Planktonic bacteria streamline their genetic makeup to become lean, mean survival machines

Planktonic bacteria inhabiting the world's oceans have streamlined their genetic makeup to become lean, mean survival machines, according to new research by an international team of researchers, including microbiologists at the University of British Columbia.

25 Jun 2013

Scientist discovers key mutations that sparked hormonal revolution 500 million years ago

Evolution, it seems, sometimes jumps instead of crawls. A research team led by a University of Chicago scientist has discovered two key mutations that sparked a hormonal revolution 500 million years ago.

25 Jun 2013

Study suggests new ways to maximize delivery of RNA strands

Nanoparticles that deliver short strands of RNA offer a way to treat cancer and other diseases by shutting off malfunctioning genes. Although this approach has shown some promise, scientists are still not sure exactly what happens to the nanoparticles once they get inside their target cells.

25 Jun 2013

UCSF scientists explore how Dact1 mutations contribute to psychiatric disorders

Gene mutations that cause cell signaling networks to go awry during embryonic development and lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism, and bipolar disorder, according to new research by UC San Francisco scientists.

25 Jun 2013

Research findings could lead to new potential treatment for multiple sclerosis

Myelin, the fatty coating that protects neurons in the brain and spinal cord, is destroyed in diseases such as multiple sclerosis. Researchers have been striving to determine whether oligodendrocytes, the cells that produce myelin, can be stimulated to make new myelin. Using live imaging in zebrafish to track oligodendrocytes in real time, researchers reporting in the June 24 issue of the Cell Press journal Developmental Cell discovered that individual oligodendrocytes coat neurons with myelin for only five hours after they are born. If the findings hold true in humans, they could lead to new treatment strategies for multiple sclerosis.

25 Jun 2013

Investigators uncover connection between tumor metabolic process and progression of kidney cancer

Investigators in The Cancer Genome Atlas (TCGA) Research Network have uncovered a connection between how tumor cells use energy from metabolic processes and the aggressiveness of the most common form of kidney cancer, clear cell renal cell carcinoma (ccRCC).

24 Jun 2013

Researchers identify biological roots of migraine from large-scale genome study

In the largest study of migraines, researchers have found 5 genetic regions that for the first time have been linked to the onset of migraine. This study opens new doors to understanding the cause and biological triggers that underlie migraine attacks.

24 Jun 2013

Researchers provide new revelations about intricate pathways involved in turning on T cells

A major study from researchers at the La Jolla Institute for Allergy and Immunology provides new revelations about the intricate pathways involved in turning on T cells, the body's most important disease-fighting cells, and was published today in the prestigious scientific journal Nature.

24 Jun 2013

Researchers find elevated antibodies to gluten proteins of wheat in children with autism

Researchers have found elevated antibodies to gluten proteins of wheat in children with autism in comparison to those without autism. The results also indicated an association between the elevated antibodies and the presence of gastrointestinal symptoms in the affected children.

21 Jun 2013

MIT study shows that SIRT1 gene plays key role in controlling circadian rhythms

Human sleeping and waking patterns are largely governed by an internal circadian clock that corresponds closely with the 24-hour cycle of light and darkness. This circadian clock also controls other body functions, such as metabolism and temperature regulation.

21 Jun 2013

Researchers discover key role of RAP1 gene in obesity

The discovery of an unexpected function for a gene that was associated to another process in the organism might be a solution in search of a problem, a clue to unsuspected connections. That is what has happened with RAP1, a gene that protects telomeres- the ends of chromosomes-after researchers from the Spanish National Cancer Research Centre surprisingly discovered its key role in obesity.

21 Jun 2013

Genetic process that promotes cervical cancer warns about anti-viral therapies in certain cases

A new understanding of the genetic process that can lead to cervical cancer may help improve diagnosis of potentially dangerous lesions for some women, and also raises a warning flag about the use of anti-viral therapies in certain cases - suggesting they could actually trigger the cancer they are trying to cure.

20 Jun 2013

Scientists create way to see structures that store memories in living brain

Oscar Wilde called memory "the diary that we all carry about with us." Now a team of scientists has developed a way to see where and how that diary is written.

20 Jun 2013

Gene switch off may increase risk of heart and blood vessel disease: Research

Risk of heart and blood vessel disease may increase when a particular gene is switched off, according to preliminary research presented at the American Heart Association's Emerging Science Series Webinar.

20 Jun 2013

Viewpoints: Urgency has slipped away for 'grand bargain'; The need to scrutinize drug competition; Restore funding to 'Meals on Wheels'

It may seem paradoxical that Congress was willing to tackle a grand bargain when the deficit problem looked big and insoluble -; but quickly lost interest as soon as the problem became more manageable. … But the reason isn't really mysterious. A grand bargain would have required both sides to swallow unpalatable compromises. It would have required Democrats to agree to cuts in future spending on Medicare and Social Security. Likewise, it would have required Republicans to accept increases in tax revenue (Doyle McManus, 6/19).

20 Jun 2013

Researchers develop method to identify aggressive prostate cancers

Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms. The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment.

20 Jun 2013

Genes News and Research

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

PLK1 crucial for proper functioning of cancer cells, researchers reveal

Study finds PTSD as risk factor for heart disease among Vietnam vets

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives FDA clearance

Planktonic bacteria streamline their genetic makeup to become lean, mean survival machines

Scientist discovers key mutations that sparked hormonal revolution 500 million years ago

Study suggests new ways to maximize delivery of RNA strands

UCSF scientists explore how Dact1 mutations contribute to psychiatric disorders

Research findings could lead to new potential treatment for multiple sclerosis

Investigators uncover connection between tumor metabolic process and progression of kidney cancer

Researchers identify biological roots of migraine from large-scale genome study

Researchers provide new revelations about intricate pathways involved in turning on T cells

Researchers find elevated antibodies to gluten proteins of wheat in children with autism

MIT study shows that SIRT1 gene plays key role in controlling circadian rhythms

Researchers discover key role of RAP1 gene in obesity

Genetic process that promotes cervical cancer warns about anti-viral therapies in certain cases

Scientists create way to see structures that store memories in living brain

Gene switch off may increase risk of heart and blood vessel disease: Research

Viewpoints: Urgency has slipped away for 'grand bargain'; The need to scrutinize drug competition; Restore funding to 'Meals on Wheels'

Researchers develop method to identify aggressive prostate cancers

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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