Genetic News and Research

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Stem cell lines are ideal research tools for designing models to understand disease progression

Scientists from King's College London have announced that 16 human embryonic stem (hES) cell lines have been approved by the US National Institutes of Health (NIH) and placed on their Stem Cell Registry, making them freely available for federally-funded research in the USA.

25 Sep 2013

Engineered nanomaterials inhalation negatively impacts gestational development in animal models

After a decade of rapidly growing industrial use, unimaginably tiny particles surround us everywhere, every day, in everything we do. Used in the manufacturing of cosmetics, clothing, paints, food, drug delivery systems and many other familiar products we all use daily, little is known about the effects these materials have on health.

25 Sep 2013

MGH researchers identify rare gene mutations that appear to cause late-onset AD

Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer's disease (AD) that strikes after the age of 60.

25 Sep 2013

$Researchers show link between FTO gene and hip fracture in women$

Researchers show link between FTO gene and hip fracture in women

Australian researchers have demonstrated a strong association between the FTO (fat and obesity) gene and hip fracture in women. While the gene is already well known to affect diabetes and obesity, this is the first study to show that its high-risk variant can increase the risk of hip fracture by as much as 82%.

25 Sep 2013

Astrazeneca Licenses 3 X-Chem Drug Discovery Programs

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24 Sep 2013

Pancreatic Cancer Imaging Agent Earns Mabvax $1.75M SBIR Award

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24 Sep 2013

NCI Funds Development Of Chrysalis’ Brain Tissue Damage Treatment

The National Cancer Institute awarded Chrysalis BioTherapeutics a $1.5 million contract to continue development of Chrysalin® to mitigate radiotherapy-induced damage to normal brain tissue. The project is a collaboration between Chrysalis, Baylor College of Medicine, and the University of Texas Medical Branch (UTMB).

24 Sep 2013

First Direct Measurement Of Spinal Cord Myelin In MS

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24 Sep 2013

Abbvie, Galapagos Ink Up To $405M CF Collaboration

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24 Sep 2013

Astrazeneca Licenses 3 X-Chem Drug Discovery Programs

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24 Sep 2013

Abbvie, Galapagos Ink Up To $405M CF Collaboration

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24 Sep 2013

New And Improved Method For Analyzing Single-Cell Gene Expression

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24 Sep 2013

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Rhythm announced today the initiation of the first of a series of clinical trials with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity in individuals with a genetic deficiency in the MC4R pathway.

24 Sep 2013

Adults across the U.S. rate childhood cancer as top priority for research into improving children's health

Adults across the U.S. rate childhood cancer as their top priority for research into improving children's health, according to a new University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health.

24 Sep 2013

First global analysis of Kawasaki disease published by PLOS ONE

After more than four decades of research, strong evidence now shows that Kawasaki disease has a distinct seasonal occurrence shared by regions across the Northern hemisphere.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

New research unveils role of ORMDL3 gene in asthma

New research from the University of Minnesota College of Veterinary Medicine has uncovered the role gene ORMDL3 plays in the disease asthma. ORMDL3, a gene recently linked to asthma susceptibility, has now been linked to the body's ability to recruit inflammatory cells during an airway allergic reaction. Study findings appear today in the journal Nature Communications.

24 Sep 2013

New diagnostic criteria for TSC appear in recent online issue of Pediatric Neurology

A paper detailing new diagnostic criteria for tuberous sclerosis complex (TSC) appears in the most recent online issue of Pediatric Neurology. The author is Hope Northrup, M.D., professor of pediatrics at The University of Texas Health Science Center at Houston (UTHealth).

24 Sep 2013

Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013