Genetic News and Research

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Orbeshield Earns Soligenix Up To $26.3M From BARDA

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19 Sep 2013

Florida Hospital To Evaluate VTT’S Alzheimer’S Biomarker Assay

VTT Technical Research Centre of Finland is taking an important step toward advancing its Alzheimer's disease biomarker by collaborating with the Florida Hospital Neuroscience Institute to evaluate screening, diagnostic, and prognostic potential of the biomarker assay and utilize it to specifically target which types of precautions to take when approaching early stages of the disease.

19 Sep 2013

BARDA Exercises $6M Option For Aeolus' Acute Radiation Syndrome Drug

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19 Sep 2013

GSK Returns Vercirnon Rights To Chemocentryx After Phase III Flop

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19 Sep 2013

arGEN-X and Shire achieve milestone in SIMPLE Antibody R&D collaboration

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces it has attained a key success milestone in its SIMPLE Antibody research and product development collaboration with the Human Genetic Therapies division of Shire Pharmaceuticals. The milestone, which triggered an undisclosed payment from Shire, was the first demonstration of in vivo proof of concept for one of the antibody discovery programs undertaken in the collaboration.

19 Sep 2013

Blood lipid marker may help predict risk for Parkinson's disease

A genetic mutation, known as GBA, that leads to early onset of Parkinson's disease and severe cognitive impairment (in about 4 to 7 percent of all patients with the disease) also alters how specific lipids, ceramides and glucosylceramides are metabolized. Mayo Clinic researchers have found that Parkinson's patients who do not carry the genetic mutation also have higher levels of these lipids in the blood. Further, those who had Parkinson's and high blood levels were also more likely to have cognitive impairment and dementia.

19 Sep 2013

Isis Pharmaceuticals announces preliminary data from ISIS-SMNRx Phase 1 study in infants with SMA

Isis Pharmaceuticals, Inc. announced today that follow-up preliminary data from a single dose, open-label Phase 1 study of ISIS-SMNRx in children with spinal muscular atrophy, show that most SMA children receiving the two highest doses of the drug (6 mg and 9 mg) continued to show improvements in muscle function tests up to 14 months after a single injection of the drug.

19 Sep 2013

Cancer Council Queensland to host free webinar for women diagnosed with breast cancer genes

Cancer Council will next week host a free national webinar for women who carry BRCA 1 or BRCA 2 genes for breast cancer.

19 Sep 2013

Domino transplant saves patient suffering from liver cancer

Tiffany Schwantes was going to die without a new liver. The 31-year old mother of two suffered from an aggressive form of liver cancer and, because of organ allocation rules, she could not be placed high enough on the liver transplant list to receive a new liver in a timely manner.

19 Sep 2013

Researchers examine evolutionary selective pressure for MC1R gene among Spaniard and European populations

The proclivity of Spaniards to bask in regions like the Costa del Sol while their northern European counterparts must stay under cover to protect their paler skin or risk skin cancer is due in large part to the pigment producing qualities of the MC1R gene locus.

19 Sep 2013

New blood test accurately differentiates viral and bacterial infections

A blood test developed by researchers at Duke Medicine showed more than 90-percent accuracy in distinguishing between viral and bacterial infections when tested in people with respiratory illnesses.

19 Sep 2013

Researchers identify likely molecular pathway that causes untreatable neurodegenerative diseases

University of Adelaide researchers have identified a likely molecular pathway that causes a group of untreatable neurodegenerative diseases, including Huntington's disease and Lou Gehrig's disease.

19 Sep 2013

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance.

19 Sep 2013

Researchers discover new way to combat HIV-1 infection

Current drug treatments for HIV work well to keep patients from developing AIDS, but no one has found a way to entirely eliminate the virus from the human body, so patients continue to require lifelong treatment to prevent them from developing AIDS.

19 Sep 2013

Wayne State University initiates groundbreaking multiple sclerosis study

A groundbreaking study in multiple sclerosis focusing on "remyelination in the brain" has been initiated by Omar Khan, M.D., professor and chair of neurology at the Wayne State University School of Medicine.

19 Sep 2013

EpimiRNA Consortium concentrates on developing novel mRNA-based therapeutics to prevent epilepsy

Over 50 million people across the world suffer from epilepsy, making it the most common serious neurological disorder for which there is no cure. The causes for epilepsy are insufficiently understood with currently available treatments being sub-optimal and with a significant proportion of patients not responding

19 Sep 2013

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

The National Human Genome Research Institute has selected the Johns Hopkins Berman Institute of Bioethics to establish a "Center of Excellence" to study the ethical, legal and social implications of genomic research.

19 Sep 2013

Promising early findings from Parkinson’s biomarker study

Early results from the Parkinson’s Progression Markers Initiative suggest that some cerebrospinal fluid biomarkers hold diagnostic and prognostic promise.

18 Sep 2013

GSK Returns Vercirnon Rights To Chemocentryx After Phase III Flop

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18 Sep 2013

Gout: An Interview with Dr. Lawrence Edwards, Chairman and CEO of GUAES

Gout is the most common form of inflammatory arthritis that affects adults. It's a disease caused by the presence of uric acid crystals in and around the joints. It's a disease that's becoming more and more common. It probably has doubled in its prevalence worldwide over the past twenty to thirty years.

18 Sep 2013