Genetic News and Research

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DIRECT project to focus on stratification of patients with type 2 diabetes

Gathering experts from 21 European academic institutions and key players of the pharmaceutical industry, the DIRECT project (DIabetes REsearch for patient straTification) will focus on the stratification of patients with type 2 diabetes in order to develop personalized treatments, that would therefore be more efficient.

23 Feb 2012

Assessing family medical history helps spot patients at high risk of heart disease

A new study by researchers at The University of Nottingham has proved that assessing family medical history is a significant tool in helping GPs spot patients at high risk of heart disease and its widespread use could save lives.

23 Feb 2012

Scientists design compounds that act against myotonic dystrophy type 1 RNA

While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed a series of small molecules that act against an RNA defect directly responsible for the most common form of adult-onset muscular dystrophy.

23 Feb 2012

Inven2, OGT enter license agreement for 12 colorectal cancer biomarkers

Oxford Gene Technology (OGT), provider of innovative clinical genetics and diagnostic solutions to advance molecular medicine, announced today that it has entered into an exclusive licensing agreement with Inven2, the technology transfer office at Oslo University Hospital (OUS) and University of Oslo (UiO), for 12 highly promising colorectal cancer tissue biomarkers.

From Oxford Gene Technology 23 Feb 2012

NK cells play an important role in rejection of porcine chondrocytes transplantation

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have studied for the first time the response of human NK cells (Natural Killer) against porcine chondrocytes (cartilage cells).

23 Feb 2012

First molecular evidence links body's natural circadian rhythms to SCD

A fundamental discovery reported in the March 1st issue of the journal Nature, uncovers the first molecular evidence linking the body's natural circadian rhythms to sudden cardiac death (SCD). Ventricular arrhythmias, or abnormal heart rhythms, are the most common cause of sudden cardiac death: the primary cause of death from heart disease.

23 Feb 2012

Insight into relationship between two types of suppressors in cancerous tumors

The University of Kentucky has announced that Dr. Daret St. Clair, the James Graham Brown Endowed Chair and professor of toxicology, has published the first comprehensive study that provides insight into the relationship between two types of suppressors in cancerous tumors. The results will enhance the understanding of transcriptional mechanisms in carcinogenesis.

23 Feb 2012

Study on role of genetics and environmental influences on criminal and antisocial behavior

An assistant professor at Sam Houston State University, College of Criminal Justice is working to unlock the mysteries surrounding the role that genetics and environmental influences play on criminal and antisocial behavior.

22 Feb 2012

Over-reactive parents more likely to have toddlers with negative emotionality, problem behaviors

Researchers have found that parents of young children who anger easily and over-react are more likely to have toddlers who act out and become upset easily.

22 Feb 2012

Childhood Obesity celebrates second anniversary of Let's Move! initiative

Faith-based advocacy has been cited as a valuable tool in combating childhood obesity, but evidence is needed to support this assertion and to define how the link between advocacy and policy can contribute to promoting permanent lifestyle changes. This article is part of a special issue of the journal Childhood Obesity celebrating the second anniversary of First Lady Michelle Obama's Let's Move! initiative.

22 Feb 2012

First study to gauge college students' willingness to donate to a genetic biobank

A majority of college students is receptive to donating blood or other genetic material for scientific research, according to a new study from Southern Methodist University, Dallas.

22 Feb 2012

OGF-OGFr axis discovery provides new insights into ovarian cancer

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the presence and integrity of the opioid growth factor receptor (OGFr), which mediates the inhibitory action of opioid growth factor (OGF) on cell proliferation, is a key to understanding the progression and treatment of human ovarian cancer.

22 Feb 2012

Mitochondria may be promising new target for cancer treatment

Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the numbers of mitochondria in cells could shrink human lung cancers transplanted into mice, a team of Chicago researchers report in the journal FASEB.

22 Feb 2012

Researchers study specially bred mice to understand annual flu epidemics

As part of a national collaboration, Oregon Health & Science University researchers are studying specially bred mice that are more like humans than ever before when it comes to genetic variation. Through these mice, the researchers hope to better understand and treat an infectious disease that plagues us year in and year out: the flu.

22 Feb 2012

DANSR/FORTE assay more effective in diagnosing Edwards and Down syndrome

Using a noninvasive test on maternal blood that deploys a novel biochemical assay and a new algorithm for analysis, scientists can detect, with a high degree of accuracy, the risk that a fetus has the chromosomal abnormalities that cause Down syndrome and a genetic disorder known as Edwards syndrome.

22 Feb 2012

Electronic properties of DNA can play a role in early diagnosis of cancer-causing mutations

Scientists have discovered that cancer-causing genetic mutations have better-disguised electronic signatures than other mutations - a trait which could help them fly under the radar of the body's defence mechanisms.

22 Feb 2012

Tasmanian devil cancer genome mapped

Researchers, including those from Wellcome Trust Sanger Institute near Cambridge, have sequenced the genome of a facial cancer that is threatening the existence of the Tasmanian devil.

21 Feb 2012

Biotech company defends patent on gene mutation for breast cancer

A US biotechnology company is defending the granting of a controversial patent over a common genetic mutation for breast cancer, rejecting accusations it amounts to the privatization of the human body.

21 Feb 2012

Genomic instability allows malignant cells to acquire more deadly characteristics

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those aps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report in an Online Now article at the journal Cell.

21 Feb 2012

Telomerase reactivation in malignant cells after genomic instability causes cancer progression

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report in the Feb. 17 issue of Cell.

21 Feb 2012

Genetic News and Research

DIRECT project to focus on stratification of patients with type 2 diabetes

Assessing family medical history helps spot patients at high risk of heart disease

Scientists design compounds that act against myotonic dystrophy type 1 RNA

Inven2, OGT enter license agreement for 12 colorectal cancer biomarkers

NK cells play an important role in rejection of porcine chondrocytes transplantation

First molecular evidence links body's natural circadian rhythms to SCD

Insight into relationship between two types of suppressors in cancerous tumors

Study on role of genetics and environmental influences on criminal and antisocial behavior

Over-reactive parents more likely to have toddlers with negative emotionality, problem behaviors

Childhood Obesity celebrates second anniversary of Let's Move! initiative

First study to gauge college students' willingness to donate to a genetic biobank

OGF-OGFr axis discovery provides new insights into ovarian cancer

Mitochondria may be promising new target for cancer treatment

Researchers study specially bred mice to understand annual flu epidemics

DANSR/FORTE assay more effective in diagnosing Edwards and Down syndrome

Electronic properties of DNA can play a role in early diagnosis of cancer-causing mutations

Tasmanian devil cancer genome mapped

Biotech company defends patent on gene mutation for breast cancer

Genomic instability allows malignant cells to acquire more deadly characteristics

Telomerase reactivation in malignant cells after genomic instability causes cancer progression

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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