Genetic News and Research

RSS

Conflicts in medical management of hemophilia

Hemophilia is a medical disorder that is part of our genetic load as humans. It will never disappear. Therefore, the only way to live with it is to receive adequate medical management. Its effects on those males who have inherited the disorder that affects their blood clotting without treatment includes recurrent hemorrhages (bleeds) into joints as well as internal bleeding. The bleeds are painful, resulting in disuse, disability and crippling. The first signs usually appear in early childhood. A child who suffers a mouth bleed can slowly lose enough blood to result in death.

8 Mar 2011

New discovery in childhood respiratory disease

Researchers have identified a critical part of the process by which one of the world's most common and dangerous early childhood infections, respiratory syncytial virus, causes disease.

8 Mar 2011

Institute for Genome Sciences plays key role in investigation of anthrax attacks

Researchers at the Institute for Genome Sciences at the University of Maryland School of Medicine and collaborators at the FBI, the U.S. Army Medical Research Institute of Infectious Diseases and Northern Arizona University have published the first scientific paper based on their investigation into the anthrax attacks of 2001.

8 Mar 2011

New clinical trial to assess antiretroviral treatment in HIV-infected individuals based on CD4 counts

A major new clinical trial seeks to determine whether HIV-infected asymptomatic individuals have less risk of developing AIDS or other serious illness if they begin taking antiretrovirals sooner rather than later, based on their level of CD4+ T-cells.

8 Mar 2011

Scientists develop new method that uncovers combined effects of genes

Scientists at the European Molecular Biology Laboratory and the German Cancer Research Centre, both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes.

8 Mar 2011

Two studies show how laminin plays a central role in breast cancer development

Laminin, long thought to be only a structural support protein in the microenvironment of breast and other epithelial tissues, is "famous" for its cross-like shape.

8 Mar 2011

New discovery can provide insight into lung cancer

A discovery at University of Colorado Cancer Center shows testing lung cancer on a molecular level can produce new insights into this deadly disease.

8 Mar 2011

New study reveals role of INK4, ARF proteins in Burkitt's lymphoma

Burkitt's lymphoma is one of the most aggressive tumors affecting humans. Multiple alterations in genes that regulate cell proliferation rate explain its aggressive behavior.

8 Mar 2011

Ambry, RainDance enter new collaboration to develop and commercialize ADME screening

RainDance Technologies, Inc. and Ambry Genetics, today announced a new collaboration focused on the development and commercialization of a comprehensive drug absorption, distribution, metabolism, and excretion genetic screening panel for use on next-generation sequencing systems.

8 Mar 2011

13 heart disease risk genes identified

Researchers have found 13 new gene variants that might increase the risk of heart disease. Heart disease being the largest killer worldwide, this discovery could shed light on causes and lead to more effective treatments.

7 Mar 2011

Down’s syndrome could be detected in mother’s blood test

European researchers have devised a blood test that could help pregnant women avoid the invasive procedures now used to diagnose Down syndrome prenatally and make the diagnosis with 100% accuracy. The study report was published this Sunday in Nature Medicine.

7 Mar 2011

New insight into coronary artery disease

Insight into the complex biological mechanisms that cause heart disease has taken a major step forward with the discovery of 13 new genes that increase the risk of coronary artery disease.

7 Mar 2011

Duchenne Parent Project awards grant to AMT for DMD gene therapy

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, announced today that the Duchenne Parent Project, based in the Netherlands, has awarded AMT a grant of EUR 145,000 to support the development of AMT-080, AMT's gene therapy for Duchenne Muscular Dystrophy.

7 Mar 2011

Study uncovers 13 new genes that increase risk of heart attacks

The largest-ever study of its type into coronary heart disease, involving scientists from the University of Leicester, has uncovered 13 new genes that increase risk of heart attacks.

7 Mar 2011

Scientists discover SNPs linked with high risk of sick sinus syndrome

Scientists at deCODE genetics and academic colleagues from Iceland, The Netherlands, Denmark, USA and Illumina, Inc., today report the discovery of single-letter variants in the sequence of the human genome associated with high risk of sick sinus syndrome.

6 Mar 2011

Researchers identify 13 new gene sites linked with risk of coronary artery disease

An international research collaboration has identified 13 new gene sites associated with the risk of coronary artery disease and validated 10 sites found in previous studies. Several of the novel sites discovered in the study, which is being published online in Nature Genetics, do not appear to relate to known risk factors, suggesting previously unsuspected mechanisms for cardiovascular disease.

6 Mar 2011

Study links 13 new gene regions to coronary atherosclerosis

Thirteen new gene regions have been convincingly linked to coronary atherosclerosis in a massive, new, international genetics study involving investigators from the Stanford University School of Medicine.

6 Mar 2011

Experts to discuss cause of sudden death on athletic playing fields

While the cause of death of the Fennville, Mich. high school basketball player is unknown, an inherited heart condition makes the top of the list for possible causes.

5 Mar 2011

Scientific symposium to examine new approaches to schizophrenia drug development

Despite significant investment in research and development by pharmaceutical companies, the last decade has seen a marked decline in the number of drugs developed and approved for schizophrenia. A multi-day symposium at the New York Academy of Sciences on Wednesday, March 9 - Friday, March 11 will convene world-leading experts in clinical, translational, and basic neuroscience to address this problem by examining novel, state-of-the-art approaches to schizophrenia drug development.

5 Mar 2011

Scientists detail role of TDP-43 in ALS pathology

Amyotrophic lateral sclerosis, known as ALS or more popularly, Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death.

5 Mar 2011