Genetic News and Research

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Scientific advances at Scripps Research lay foundation for new lupus drug Benlysta

Scientific advances at The Scripps Research Institute were key to laying the foundation for the new drug Benlysta® (belimumab), approved today by the U.S. Food and Drug Administration. Benlysta®, which treats the most common type of lupus, is the first in a new class of pharmaceuticals that prevents the body from attacking its own critical tissues.

11 Mar 2011

Genetic variant contributes to higher risk of lung cancer, increases tendency to smoke more

Norwegian researchers have discovered genes that increase not only one's risk of lung cancer, but perhaps one's urge to smoke as well. Now these researchers are working on developing a blood test for lung cancer.

11 Mar 2011

Erlotinib, Gefitinib effective in treating certain subset of advanced NSCLC patients

LSU oncologist Vince D. Cataldo, MD, is the lead author of a review article reporting two chemotherapy drugs now indicated for second and third-line therapy in patients with advanced non-small-cell lung cancer are remarkably effective in treating a certain subset of these patients.

11 Mar 2011

Discovery: VPS4A enzyme plays a key role in release of HIV particles

Human Immunodeficiency Virus - which causes AIDS - invades human immune cells and causes them to produce new copies of the virus, which can then infect new cells.

11 Mar 2011

Study sheds light on how signals from CSF help drive neural development

Cerebrospinal fluid, the fluid found in and around the brain and spinal cord, may play a larger role in the developing brain than previously thought, according to researchers at Children's Hospital Boston.

11 Mar 2011

Majority of Americans support government involvement in distribution of genetic test

A report released by Cogent Research reveals that a majority of Americans support government involvement in the distribution of direct-to-consumer genomics-based tests.

11 Mar 2011

Scientists discover four new genetic variants in humans linked with NAFLD

Five genetic variants in humans - four new - associate with Nonalcoholic Fatty Liver Disease, according to a study published March 10 in PLoS Genetics.

10 Mar 2011

Scientists develop new model for neurodegenerative disease

A team of scientists at the University of California, San Francisco has developed a new model for how inherited genes contribute to a common but untreatable and incurable neurodegenerative disease.

10 Mar 2011

TGen launches globalCure initiative to fight against pancreatic cancer

In an effort to improve treatment and one day find a cure for pancreatic cancer, the TGen Foundation today joined with key donors and community leaders to announce the creation of globalCure.

10 Mar 2011

New book on craniosynostosis

Craniosynostosis - the premature fusion of the cranial sutures of an infant's skull - is a challenging and complex condition that can occur as part of a syndrome or in isolation.

10 Mar 2011

Research: CREBBP mutation may help cancer resist steroid treatment, fuel ALL's return

Despite dramatically improved survival rates for childhood acute lymphoblastic leukemia, relapse remains a leading cause of death from the disease. Work led by St. Jude Children's Research Hospital investigators identified mutations in a gene named CREBBP that may help the cancer resist steroid treatment and fuel ALL's return.

10 Mar 2011

ALR commits funding for new study to identify lupus susceptibility genes in multiple ethnicities

The Alliance for Lupus Research (ALR) – the world's largest private funder of lupus research – today announced funding of an important new study to identify lupus susceptibility genes in multiple ethnicities including African Americans, who are three times more likely than Caucasians to have the disease.

10 Mar 2011

New study sheds 'light' on intricate brain cell connections responsible for anxiety

A new study sheds light--both literally and figuratively--on the intricate brain cell connections responsible for anxiety.

10 Mar 2011

Swine flu virus may evolve into a deadlier form

In the fall of 1917, a new strain of influenza swirled around the globe. At first, it resembled a typical flu epidemic: Most deaths occurred among the elderly, while younger people recovered quickly. However, in the summer of 1918, a deadlier version of the same virus began spreading, with disastrous consequence. In total, the pandemic killed at least 50 million people - about 3 percent of the world's population at the time.

10 Mar 2011

Vascular disorder of the brain most frequently misdiagnosed as multiple sclerosis

A devastating vascular disorder of the brain called CADASIL, which strikes young adults and leads to early dementia, often is misdiagnosed as multiple sclerosis, Loyola University Health System researchers report.

10 Mar 2011

CUBN gene mutation linked with albuminuria in individuals with or without diabetes

A team of researchers from the United States and Europe has identified a single genetic mutation in the CUBN gene that is associated with albuminuria both with and without diabetes. Albuminuria is a condition caused by the leaking of the protein albumin into the urine, which is an indication of kidney disease.

9 Mar 2011

Geospiza, NuGEN partner to develop seamless next-generation sequencing workflow

Geospiza, Inc., the market leading developer of genetic analysis software, and NuGEN Technologies, Inc., the leader in sample preparation solutions for clinical samples, today announced a co-marketing agreement to develop a seamless next-generation sequencing workflow to accelerate discoveries for large disease research studies.

9 Mar 2011

Parkinson's disease medication turns on critical gene, protects brain cells

In a major breakthrough in the battle against Parkinson's disease, researchers at the University of Colorado School of Medicine have discovered a drug that stops the progression of the degenerative illness in mice and is now being tested in humans.

9 Mar 2011

USPTO grants new patent to Intellect's Alzheimer's vaccine

Intellect Neurosciences, Inc., a biopharmaceutical company with an internal preclinical and clinical-stage pipeline and licenses with major pharmaceutical companies covering products in late-stage clinical trials, announced today that it has received a new patent from the United States Patent and Trademark Office in relation to the Company's RECALL-VAXTM technology platform.

9 Mar 2011

Psychosocially hazardous neighborhood may influence cognitive function in older age

Residing in a psychosocially hazardous neighborhood is associated with worse cognitive function in older age for persons with the apolipoprotein E ε4 allele, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

9 Mar 2011

Genetic News and Research

Scientific advances at Scripps Research lay foundation for new lupus drug Benlysta

Genetic variant contributes to higher risk of lung cancer, increases tendency to smoke more

Erlotinib, Gefitinib effective in treating certain subset of advanced NSCLC patients

Discovery: VPS4A enzyme plays a key role in release of HIV particles

Study sheds light on how signals from CSF help drive neural development

Majority of Americans support government involvement in distribution of genetic test

Scientists discover four new genetic variants in humans linked with NAFLD

Scientists develop new model for neurodegenerative disease

TGen launches globalCure initiative to fight against pancreatic cancer

New book on craniosynostosis

Research: CREBBP mutation may help cancer resist steroid treatment, fuel ALL's return

ALR commits funding for new study to identify lupus susceptibility genes in multiple ethnicities

New study sheds 'light' on intricate brain cell connections responsible for anxiety

Swine flu virus may evolve into a deadlier form

Vascular disorder of the brain most frequently misdiagnosed as multiple sclerosis

CUBN gene mutation linked with albuminuria in individuals with or without diabetes

Geospiza, NuGEN partner to develop seamless next-generation sequencing workflow

Parkinson's disease medication turns on critical gene, protects brain cells

USPTO grants new patent to Intellect's Alzheimer's vaccine

Psychosocially hazardous neighborhood may influence cognitive function in older age

Sequencing & Genomics: Elevating Science and Healthcare eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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