Genetic News and Research

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Proteomic analysis of human amniotic fluid

Researchers report in the August issue of Molecular & Cellular Proteomics the most complete list so far of proteins present in the human amniotic fluid, the liquid that surrounds a fetus during pregnancy.

24 Aug 2007

Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Migration of antibiotic resistance from animal feeding operations into groundwater

The routine use of antibiotics in swine production can have unintended consequences, with antibiotic resistance genes sometimes leaking from waste lagoons into groundwater.

22 Aug 2007

High altitude pulmonary oedema

Experts at the University are studying an illness known as HAPE (high altitude pulmonary oedema), which causes fluid to build up in the lungs can and can occur from as low as 2,500 metres, affecting people of all age groups and fitness levels.

22 Aug 2007

Genetics determine optimal drug dose of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood , the journal of the American Society of Hematology.

22 Aug 2007

Traffic and childhood asthma

Children who carry variations in specific genes that metabolize vehicle emissions are more susceptible to developing asthma, particularly if they live near major roadways, a study led by researchers at the University of Southern California (USC) suggests.

22 Aug 2007

Exhaust fumes increase risk for asthma in genetically susceptible children

Exhaust fumes heighten the risk of asthma in children who are already genetically susceptible to respiratory disease, indicates research published ahead of print in the journal Thorax.

22 Aug 2007

Claims of sex-related differences in genetic association insufficiently documented or spurious

A review of previous research suggests that prominent claims of sex differences of gene-disease associations are often insufficiently documented and validated, according to an article in the August 22/29 issue of JAMA.

22 Aug 2007

New Cockayne syndrome discovery

Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have shown that the genetic defect that causes Cockayne Syndrome affects a key function of the cell – the transcription of genes coding for ribosomal RNA.

21 Aug 2007

Genetic testing can be used to help personalize the therapeutic dosage of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood, the journal of the American Society of Hematology.

21 Aug 2007

Breast feeding mothers warned of risks of Codeine for babies

The Food and Drugs Administration (FDA) in the United States has issued a warning to nursing mothers regarding the pain-killer codeine.

20 Aug 2007

Organ-transplant drug may help fight lupus

A compound related to a drug used in humans to prevent organ-transplant rejection attacks a key biochemical process in the faulty immune cells of lupus-prone mice, suggesting a possible new approach to combating the disease, UT Southwestern Medical Center researchers have found.

17 Aug 2007