Genetic News and Research

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Genetics of bipolar disorder

The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows.

9 May 2007

Gene mutation linked to cognition is found only in humans

The human and chimpanzee genomes vary by just 1.2 percent, yet there is a considerable difference in the mental and linguistic capabilities between the two species.

9 May 2007

VCU to develop new form of radiation therapy

The National Cancer Institute has awarded a five-year, $10.7 million grant to Virginia Commonwealth University Massey Cancer Center researchers to develop a new form of radiation therapy that will enable the safe administration of more aggressive cancer treatments.

9 May 2007

Low glucose levels offer clue to infant cot deaths

Researchers in Scotland have found what they believe is a link between infant cot deaths and low blood glucose levels.

9 May 2007

Novel therapies to prevent metastasis

In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor.

8 May 2007

Study looks at interest level of healthy, young adults in receiving genetic testing for common conditions

The National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), parts of the National Institutes of Health (NIH), have teamed with Group Health Cooperative in Seattle and Henry Ford Health System in Detroit to launch a study to investigate the interest level of healthy, young adults in receiving genetic testing for eight common conditions.

8 May 2007

Social behavior differs in children with family history of autism

The baby brothers and sisters of autistic children do not seek emotional cues from adults, or respond to them, as often as other toddlers do, suggests new research from the University of California, San Diego.

8 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

Sperm from diabetic men have greater levels of DNA damage which may affect their fertility

In the first study to compare the quality of DNA in sperm from diabetic and non-diabetic men, researchers at Queen’s University Belfast showed that the DNA in the nuclei of the sperm cells had greater levels of fragmentation in diabetic men, and that there were more deletions of DNA in the tiny, energy-generating structures in the cells called mitochondria.

8 May 2007

New mapping technique will answer fundamental questions about chromosome structure

Researchers at the University of Illinois have developed a simple and economical technique for imaging and mapping fruit fly chromosomes.

8 May 2007

Current approach to drug discovery for Lou Gehrig's disease be re-examined

Most research on Lou Gehrig's disease therapeutics has been based on the assumption that its two forms (sporadic and hereditary) are similar in their underlying cause.

8 May 2007

Little-known cell networks vital to circadian rhythm

Circadian rhythm is the basic 24-hour cycle that involves various behaviors, including sleeping and eating, in all living organisms.

4 May 2007

New understanding of genetic mutation that contributes to autism

The investigators now know more about how the mutation causes problems with a specific gene and are testing for additional mutations of the same gene in other people with autism.

4 May 2007

Master regulator for epithelial tissue regeneration found

The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes.

4 May 2007

Nutrient "floodgate" protects against inflammatory immune response

After every meal, the body must prevent the immune system from launching an all-out fight against food.

4 May 2007

People with a sibling who have had a stroke are almost twice as likely to suffer a stroke themselves

People with a brother or sister who have had a stroke are almost twice as likely as the average American to suffer a stroke themselves, according to research presented at the American Academy of Neurology's 59th Annual Meeting in Boston.

4 May 2007

Men and women at risk for alcohol dependence are more likely to choose a mate who also is at risk

Alcoholism is more common among partners of alcoholics than among partners of non-alcoholics, but it isn't as common as it might be. The researchers found that in some cases, one spouse's excesses with alcohol actually could help protect the other from alcohol dependence.

4 May 2007