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Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Researchers from the Johns Hopkins Kimmel Cancer Center, Indiana University and the University of Michigan have found that some women have a gene mutation that may decrease the effectiveness of tamoxifen, a commonly used breast cancer drug.

7 Jun 2004

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

A chemotherapy regimen commonly used to treat non-small cell lung cancer is both more effective and more toxic in Japanese patients than in American patients, researchers reported Saturday at the annual meeting of the American Society of Clinical Oncologists.

7 Jun 2004

New study to determine the effectiveness of a new pediatric screening method for Wilson's disease

Mayo Clinic seeks normal healthy children and young adults between the ages of 3 months and 18 years for a research study to determine the effectiveness of a new pediatric screening method for Wilson's disease.

7 Jun 2004

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

A biological agent — a drug that wraps vitamin A inside bubbles of fat — used without chemotherapy appears to offer as many as one-third of patients with a rare form of leukemia an opportunity for a long-term, disease-free future, say researchers at The University of Texas M. D. Anderson Cancer Center.

7 Jun 2004

Crucial discovery may help better diagnose and treat children with Hirschsprung disease

Researchers at Fox Chase Cancer Center have made a crucial discovery that may help physicians better diagnose and treat children with Hirschsprung disease, a debilitating and sometimes life-threatening ailment that causes bowel obstruction and involves an array of genetic changes.

5 Jun 2004

High school student makes significant contribution to breast cancer research

A high school student from Albany, New York, has made a significant contribution toward understanding how mutations to a gene called BRCA-1 contributes to hereditary breast cancer.

5 Jun 2004

Polycystic ovary syndrome more common than originally thought

Researchers at Cedars-Sinai Medical Center and the University of Alabama, Birmingham, have found that a complex hormonal disorder affecting the reproductive and metabolic function of premenopausal women may be considerably more common in the United States than previously believed from earlier, smaller studies.

5 Jun 2004

New generation drug therapy targets the individual

The days of ‘one size fits all’ medicines may soon be a thing of the past for people undergoing radical drug therapies for chronic or serious illnesses.

5 Jun 2004

Breakthrough in gene therapy

Despite a roller-coaster ride of ups and downs during the past 15 years, gene therapy has continued to attract many of the world's brightest scientists. They are tantalized by the enormous potential that replacing missing genes or disabling defective ones offers for curing diseases of many kinds.

3 Jun 2004

Fibroid tumors lack crucial structural protein

Fibroid tumors-the sometimes painful uterine growths affecting many American women-lack a key protein that plays a role in holding tissues together, according to a study by researchers from the Uniformed Services University of the Health Sciences (USUHS) and the National Institute of Child Health and Human Development of the National Institutes of Health

3 Jun 2004

Compulsive hoarding study could improve diagnosis and treatment of psychiatric disorders

A PET imaging study conducted at the UCLA Neuropsychiatric Institute indicates the neurobiology of America's estimated 1 million compulsive hoarders differs significantly from people with other obsessive-compulsive disorder (OCD) symptoms. The findings indicate that different medications could improve treatment success.

2 Jun 2004

Fibroid tumors affecting many American women lack a key protein helps hold tissues together

Fibroid tumors — the sometimes painful uterine growths affecting many American women — lack a key protein that plays a role in holding tissues together, according to a study by researchers from the Uniformed Services University of the Health Sciences (USUHS) and the National Institute of Child Health and Human Development of the National Institutes of Health.

2 Jun 2004

Study may help oncologists tailor chemotherapy to patients based on their genetic make-up

Genetic variations in an individual’s ability to repair DNA damage may help predict survival in lung cancer patients treated with the common chemotherapy drugs cisplatin or carboplatin, a new study shows.

2 Jun 2004

Why do grandparents systemically prefer some grandchildren to others?

“Maternal grandmothers are closer to their grandchildren than other grandparents. The next closest relationship between grandparents and grandchildren is by maternal grandfathers, then paternal grandmothers and, last of all, paternal grandfathers.”

2 Jun 2004

Suprising discovery in the retinas of colorblind people may help understanding of a number of eye disorders

The discovery of a surprise lurking in the retinas of colorblind people may have ramifications for understanding a number of eye disorders. Using a technique called “adaptive optics,” which was originally developed to help astronomers see more clearly through the Earth’s atmosphere.

2 Jun 2004

Genetic News and Research

Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

New study to determine the effectiveness of a new pediatric screening method for Wilson's disease

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

Crucial discovery may help better diagnose and treat children with Hirschsprung disease

High school student makes significant contribution to breast cancer research

Polycystic ovary syndrome more common than originally thought

New generation drug therapy targets the individual

Breakthrough in gene therapy

Fibroid tumors lack crucial structural protein

Compulsive hoarding study could improve diagnosis and treatment of psychiatric disorders

Fibroid tumors affecting many American women lack a key protein helps hold tissues together

Study may help oncologists tailor chemotherapy to patients based on their genetic make-up

Why do grandparents systemically prefer some grandchildren to others?

Suprising discovery in the retinas of colorblind people may help understanding of a number of eye disorders

Genes that allow nerve cells to communicate may have come from bacteria eons ago

Research laboratory at the forefront of the science of metabolomics

New medical patent covering the generation of genetically enhanced therapeutic antigens

Mice may hold the key to longer life

Reiner Center for Behavioral and Psychosomatic Medicine

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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