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Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.

2 Aug 2022

Newly developed nanobodies could eventually be used to treat neurocognitive disorders

Proteins called antibodies help the immune system find and attack foreign pathogens. Mini versions of antibodies, called nanobodies — natural compounds in the blood of animals such as llamas and sharks — are being studied to treat autoimmune diseases and cancer.

1 Aug 2022

Researchers find mechanisms behind the development of congenital birth defect

About one percent of the world population is born with a congenital heart defect, which affects about 40,000 U.S. births each year, but how these particular birth defects come about is largely unknown.

1 Aug 2022

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

Fuzhong Zhang, professor of energy, environmental and chemical engineering at the McKelvey School of Engineering, has developed a synthetic biology platform to produce muscle fibers that are strong, tough and can absorb energy in ways very similar to the real thing.

29 Jul 2022

Newly developed nanobody can get through tough brain cells and treat Parkinson’s disease

Proteins called antibodies help the immune system find and attack foreign pathogens. Mini versions of antibodies, called nanobodies -; natural compounds in the blood of animals such as llamas and sharks -; are being studied to treat autoimmune diseases and cancer.

28 Jul 2022

Creating a Microrobot to One Day Tackle Cancer

In this interview, we speak to Birgül Akolpoglu about her latest research into microrobotics and how these biohybrid microrobots could one day be used to tackle cancer.

27 Jul 2022

New 'decoy receptor' molecules inhibit growth of multiple myeloma and diffuse large B cell lymphoma in mice

Researchers at Stanford University have developed "decoy receptor" molecules that inhibit the growth of both multiple myeloma (MM) and diffuse large B cell lymphoma (DLBCL) in mice.

26 Jul 2022

Scientists discover a surprising link between mitochondria, inflammation and DNMT3A and TET2 genes

Mitochondria are known as cells' powerhouses, but mounting evidence suggests they also play a role in inflammation. Scientists from the Salk Institute and UC San Diego published new findings in Immunity on July 26, 2022, where they examined human blood cells and discovered a surprising link between mitochondria, inflammation and DNMT3A and TET2-; two genes that normally help regulate blood cell growth but, when mutated, are associated with an increased risk of atherosclerosis.

26 Jul 2022

Using CRISPR to Lift the Lid on Probiotics

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

26 Jul 2022

Defect in a protein causes motor disorders in flies

Researchers at the Universities of Bonn and Osnabrück have discovered a protein whose defect causes motor disorders in flies.

22 Jul 2022

Improving the immune defenses against blood cancer

For patients with lymphoma, multiple myeloma, or certain types of leukemia, treatment with chimeric antigen receptor T cells (CAR T cells) is sometimes the last chance of overcoming the cancer.

22 Jul 2022

Study assesses eight de novo genome assembly software tools on viral next-generation sequencing data

A new study compares and assesses eight de novo genome assembly software tools on actual viral next-generation sequencing data.

20 Jul 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

A recent study discusses the use of commensal bacteria in the gut and/or respiratory tract to deliver viral antigens to the host, thus acting as vaccines

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Researchers screened bacterial mucosal vaccine vectors from 2015 to the present to identify a promising candidate to present SARS-CoV-2 spike protein or its fragments.

18 Jul 2022

Cytokine-based cancer immunotherapy: current progress and future prospects

In this interview, News-Medical talks to Dr. Shuang Zhou about cytokine-base cancer immunotherapy, the current state of the field, and future prospects.

From Sino Biological Inc. 18 Jul 2022

Proteins' wobbles, shakes and quivers play a key role in their ability to function

Johns Hopkins Medicine scientists report they have probed the atomic structure of proteins to add to evidence that the wobbles, shakes and quivers of proteins play a critical role in their ability to function.

15 Jul 2022

WHO issues an urgent call to accelerate access to genomics in resource-poor countries

The World Health Organization (WHO) has issued an urgent call to accelerate access to genomics, especially in resource-poor countries, in a report that examines technology gaps and opportunities.

15 Jul 2022

New wireless technology remotely activates specific brain circuits in under one second

A research team led by Rice University neuroengineers has created wireless technology to remotely activate specific brain circuits in fruit flies in under one second.

15 Jul 2022

Genetic Engineering News and Research

Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Newly developed nanobodies could eventually be used to treat neurocognitive disorders

Researchers find mechanisms behind the development of congenital birth defect

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

Newly developed nanobody can get through tough brain cells and treat Parkinson’s disease

Creating a Microrobot to One Day Tackle Cancer

New 'decoy receptor' molecules inhibit growth of multiple myeloma and diffuse large B cell lymphoma in mice

Scientists discover a surprising link between mitochondria, inflammation and DNMT3A and TET2 genes

Using CRISPR to Lift the Lid on Probiotics

Defect in a protein causes motor disorders in flies

Improving the immune defenses against blood cancer

Study assesses eight de novo genome assembly software tools on viral next-generation sequencing data

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Cytokine-based cancer immunotherapy: current progress and future prospects

Proteins' wobbles, shakes and quivers play a key role in their ability to function

WHO issues an urgent call to accelerate access to genomics in resource-poor countries

New wireless technology remotely activates specific brain circuits in under one second

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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