Genetic Engineering News and Research

RSS

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

In health care, perhaps no word sends a more chilling message than "cancer." Brain tumors, for example, prove especially resistant to current treatments. Only 5% of patients with that condition survive more than three years and the median survival time is 10 to 14 months.

12 May 2022

Rural California hatches plan for engineered mosquitoes to battle stealthy predator

Bryan Ruiz moved his family into a newly built home in this Central Valley farming center seven months ago and almost immediately found they were under assault.

10 May 2022

New insights into the cellular and molecular mechanisms of absence seizures

Bochum researchers have gained new insights into the cellular and molecular mechanisms of absence seizures and potential therapy options.

4 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

Using silk proteins for tendon repair

Just mentioning a ruptured Achilles tendon would make anyone wince. Tendon injuries are well known for their lengthy, difficult and often incomplete healing processes.

3 May 2022

New technology to make temporary genetic modifications tested in mosquitoes

Texas A&M AgriLife Research scientists have tested a technology to make temporary genetic modifications in mosquitoes. The modifications self-delete over time.

3 May 2022

Study reveals new approach for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds.

29 Apr 2022

Dual release microparticle system promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats.

21 Apr 2022

Scientists identify innovative treatment approach for arterial thromboses

Scientists have shown in an animal model that the CXCL12 messenger could be suitable as a target structure for the treatment of blood-clotting disorders.

21 Apr 2022

Researchers identify brain areas that control the ability to perform complex, sequential movements

In a novel set of experiments with mice trained to do a sequence of movements and "change course" at the spur of the moment, Johns Hopkins scientists report they have identified areas of the animals' brains that interact to control the ability to perform complex, sequential movements, as well as to help the mice rebound when their movements are interrupted without warning.

21 Apr 2022

Study explores microbial genetic engineering approach as a replacement for shark livering for squalene

A new study examined possible genetic engineering approaches that could be utilized to tailor the metabolic processes of yeasts, bacteria, and thraustochytrids to optimize the synthesis of squalene.

21 Apr 2022

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

20 Apr 2022

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

In proof-of-concept experiments, Johns Hopkins Medicine scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, potentially advancing efforts to treat muscle injuries and muscle-wasting disorders in people.

20 Apr 2022

New technology enables single-cell sorting based on functional outputs

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

20 Apr 2022

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.

18 Apr 2022

Researchers uncover a key regulator of pregnancy-associated heart growth

Northwestern Medicine scientists have uncovered a key regulator of pregnancy-associated heart growth, according to a recent study published in the Journal of Clinical Investigation.

18 Apr 2022

Exploring strategies for successful delivery of messenger RNA therapeutics

Researchers reviewed the material properties and administration routes that could successfully deliver a messenger ribonucleic acid therapeutic agent to its targeted site.

14 Apr 2022

Mutant mice with a human gene variant exhibits ADHD-like problems

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

7 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Researchers developed a method for tracking the binding of the receptor-binding domain of SARS-CoV-2 in vivo using genetically engineered extracellular vesicles that can migrate to ACE2 expressing cells.

30 Mar 2022