Genetic Engineering News and Research

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Human iPSCs make more tiny 'cargo packets' to deliver cellular aging therapies

Johns Hopkins scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells, make tiny "cargo packets" able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells.

From Johns Hopkins Medicine 8 May 2019

Cellular mechanism blocking retina regeneration discovered

A discovery opens the possibility of one day restoring loss of vision by activating the retina's ability to regenerate.

7 May 2019

Researchers develop new molecule that binds to the cerebrovascular system

Brazilian and US researchers have developed a molecule called FRW that, in tests with mice, proved capable of binding to blood vessels in the brain but not in other organs when injected into the bloodstream.

7 May 2019

Increasing early beta-cell proliferation could halt development of type 1 diabetes

Many in-development cures for type 1 diabetes have understandably focused on tackling the autoimmune aspect of the disease before figuring out a way to replace the destroyed beta cells. But what if focusing on the beta cells first could prevent their destruction altogether?

7 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Mount Sinai study provides fresh insights into cellular pathways that cause cancer

Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene--which is often overexpressed in cancer--finding that when it acts with a specific protein, it can lead to cancer cell death.

2 May 2019

Will gene-editing of human embryos ever be justifiable?

World-leading medical ethicist Professor Arthur Caplan has published a series of recommendations with the aim of addressing worldwide concerns over gene editing of human embryos.

30 Apr 2019

UAB professor honored with the most prestigious prize for research in polycystic kidney disease

Bradley K. Yoder, Ph.D., professor and chair of the Department of Cell, Developmental and Integrative Biology at the University of Alabama at Birmingham, has been awarded with a Lillian Jean Kaplan International Prize for Advancement for his significant research in the polycystic kidney field.

29 Apr 2019

Delving into tumor's cellular lineage may offer clues for customized therapies

To explain a person's actions in the present, it sometimes helps to understand their past, including where they come from and how they were raised.

25 Apr 2019

UAB receives $17 million grant to explore immune cells in inaccessible tissues of the human body

University of Alabama at Birmingham researchers will receive $17.8 million in federal funding to attack a key "knowledge gap" in human immunology -- how the B cells and antibody-secreting cells that reside in tissues and organs differ from those found in blood.

23 Apr 2019

Scientific breakthrough provides new hope for people living with multiple sclerosis

A scientific breakthrough provides new hope for millions of people living with multiple sclerosis. Researchers at Oregon Health & Science University have developed a compound that stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord.

19 Apr 2019

Drug that treats high blood pressure shows promise against neurodegenerative diseases

A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge.

19 Apr 2019

Novel system enables researchers to study bacteria within mini-tissues in a dish

Engineering bacteria to intelligently sense and respond to disease states, from infections to cancer, has become a promising focus of synthetic biology.

19 Apr 2019

IDT partners with iGEM to support young researchers and promote scientific progress

As an advocate for researchers in synthetic biology, Integrated DNA Technologies is once again proudly partnering with the International Genetically Engineered Machine Foundation to support young researchers and promote scientific progress.

From Integrated DNA Technologies 17 Apr 2019

Novel serum biomarkers to detect NAFLD-related fibrosis

With an estimated 25% of people worldwide affected by nonalcoholic fatty liver disease (NAFLD), there is a large unmet need for accurate, noninvasive measures to enhance early diagnosis and screening of hepatic fibrosis.

16 Apr 2019

Growth hormone acts directly on the brain to conserve energy when the body loses weight

Researchers at the University of São Paulo in Brazil have discovered that growth hormone (GH), which stimulates skeletal maturation and linear bone growth, as well as helping maintain tissue and organs throughout life, also acts directly on the brain to conserve energy when the body loses weight.

12 Apr 2019

New genetic treatment removes antibiotic resistance from bacteria

Jane and Aatos Erkko foundation has awarded University of Jyväskylä'sAcademy Research Fellow Matti Jalasvuori's research group 255 000 euro grant for investigating the conjugative transfer of anti-antibiotic resistance genetic elements.

12 Apr 2019

Researchers identify rare SRC-1 gene variants related to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side.

12 Apr 2019

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Two top researchers at the Ohio University Heritage College of Osteopathic Medicine are working with two other institutions on a federally funded project to investigate why Hispanics are more prone to develop non-alcoholic fatty liver disease.

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

Genetic Engineering News and Research

Human iPSCs make more tiny 'cargo packets' to deliver cellular aging therapies

Cellular mechanism blocking retina regeneration discovered

Researchers develop new molecule that binds to the cerebrovascular system

Increasing early beta-cell proliferation could halt development of type 1 diabetes

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

Mount Sinai study provides fresh insights into cellular pathways that cause cancer

Will gene-editing of human embryos ever be justifiable?

UAB professor honored with the most prestigious prize for research in polycystic kidney disease

Delving into tumor's cellular lineage may offer clues for customized therapies

UAB receives $17 million grant to explore immune cells in inaccessible tissues of the human body

Scientific breakthrough provides new hope for people living with multiple sclerosis

Drug that treats high blood pressure shows promise against neurodegenerative diseases

Novel system enables researchers to study bacteria within mini-tissues in a dish

IDT partners with iGEM to support young researchers and promote scientific progress

Novel serum biomarkers to detect NAFLD-related fibrosis

Growth hormone acts directly on the brain to conserve energy when the body loses weight

New genetic treatment removes antibiotic resistance from bacteria

Researchers identify rare SRC-1 gene variants related to human obesity

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Biochemistry eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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