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ESMO: New system to rank relevance of treatable cancer genetic mutations needed

ESMO, the leading professional organization for medical oncology, welcomes the latest reports from The Cancer Genome Atla as a major resource for researchers across the world and calls for increased across-the-board commitment to translate these efforts into medical advances for the benefit of cancer patients.

11 Apr 2018

Researchers discover how 'junk DNA' plays key role in holding the genome together

Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be "junk DNA," plays a crucial role in holding the genome together.

11 Apr 2018

Sanford Research summit focuses on health of rural and Native American communities

The health of rural and Native American populations will be the focus of an upcoming summit with Sanford Health.

11 Apr 2018

Novel tool successfully predicts outcomes for lung cancer

Researchers have used open source data to develop a personalized risk assessment tool that can predict survival rate and treatment outcomes among patients with early-stage lung cancer.

11 Apr 2018

Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Newly discovered predictive biomarkers could help assess level of glioma recurrence risk

Researchers have identified specific predictive biomarkers that could help assess the level of risk for recurrence in patients with malignant glioma. The study, led by Henry Ford Health System's Department of Neurosurgery and Department of Public Health Sciences, was published today in Cell Reports.

10 Apr 2018

New blood test may predict future heart disease risk

Despite heart disease and type 2 diabetes being among the leading causes of death in the U.S., the mechanisms leading to and linking these two diseases remain incompletely understood.

10 Apr 2018

UCLA researchers tweak CRISPR to accelerate genomic editing

The powerful gene-editing tool, CRISPR, has revolutionized research by allowing scientists to snip and patch DNA with remarkable precision. But tracking the impact of these changes on gene function can be time-consuming. Researchers currently analyze each edit one at a time, a process that can take weeks.

9 Apr 2018

Hypercaloric food intake promotes major behavioral and cognitive changes

Mice fed on a high fat or chocolate-based diet show abnormal feeding behaviors such as snacking, bingeing and disrupted eating patterns, according to new research from scientists at the Centre for Genomic Regulation and the Pompeu Fabra University in Barcelona, Spain.

9 Apr 2018

Scientists develop indices that provide information about prognosis of cancers

Researchers from the School of Medicine in Ribeirão Preto, at the University of São Paulo, in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy to be used and identify potential targets for the development of new drugs.

6 Apr 2018

Largest genomic analysis supports additional classification of tumors

University of North Carolina Lineberger Comprehensive Cancer Center researchers are reporting the concluding findings from a major analysis of nearly 10,000 different tumor samples that focused on identifying similarities between cancers based on changes in their genes, and the way their genes are expressed.

6 Apr 2018

Research provides new insights about gender differences in airway disease risk

Human airways already demonstrate gender-based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.

6 Apr 2018

Agilent and BioTek announce new integrated metabolic analysis and imaging solution

Agilent Technologies Inc. and BioTek Instruments, Inc., today announced a new, integrated solution that combines cellular metabolic analysis and imaging technologies.

From Agilent Technologies 6 Apr 2018

Negative fateful life events appear to accelerate brain aging, study finds

Conflict, a death in the family, financial hardship and serious medical crises are all associated with accelerated physical aging. In a new study, researchers at the University of California San Diego School of Medicine found that such negative fateful life events -- or FLEs -- appear to also specifically accelerate aging in the brain.

5 Apr 2018

Study provides systematic view of gene enhancer activity in diverse tumors

At the heart of any cancer diagnosis or treatment are cells. If one thinks of the cell components controlling gene activation as a Russian nesting-doll of gene regulatory layers, within those increasingly smaller tiers are short pieces of non-coding DNA called enhancers.

5 Apr 2018

Genetic testing could help guide blood-thinner treatment after stent placement

Using genetic testing to inform which blood thinner to use following a procedure to open narrowed blood vessels resulted in significantly fewer complications among patients, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

3 Apr 2018

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Most of the human genome - 98 percent - is made up of DNA but doesn't actually encode genes, the recipes cells use to build proteins.

2 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

Researchers untap potential of wearable sensors and AI technologies to predict biological age

Researchers from the longevity biotech company GERO and Moscow Institute of Physics and Technology have shown that physical activity data acquired from wearables can be used to produce digital biomarkers of aging and frailty.

30 Mar 2018

Genomic test effective for detecting Lynch syndrome in CRC patients

A single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than the traditional multiple, sequential testing approach, according to new clinical data reported by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

29 Mar 2018