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Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Scientists discover five new regions of the genome that increase asthma risk

An international study led by scientists from Inserm and Paris Diderot Universit, the University of Chicago, the National Heart and Lung Institute and the University of Colorado Anschutz Medical Campus together with researchers of the Trans-National Asthma Genetics Consortium has discovered five new regions of the genome that increase the risk of asthma.

22 Dec 2017

Findings provide better understanding of thyroid hormones' role in mammalian seasonal changes

Researchers now have a better understanding of the role that thyroid hormones, the tissues that produce them, and the biochemical pathways on which they act have in driving seasonal reproduction in some mammals, and how this new information may help explain seasonal changes in metabolism and mood that affect humans.

21 Dec 2017

Gene editing shows promise to help people at risk of hearing loss

Gene editing could someday help people at risk of hearing loss from genetic mutations, according to research by a new Rice University faculty member.

20 Dec 2017

Certain brain tumor patients more likely to receive short hospice services, study finds

While more than 60 percent of patients with the brain tumors called malignant gliomas enroll in hospice services, almost a quarter of them do so within a week of death, probably too late for patients and family members to benefit from hospice care.

20 Dec 2017

Study identifies potential markers for early diagnosis, treatment of oral tongue cancer

Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. Patients with the disease often find it difficult to eat, swallow food, or speak.

19 Dec 2017

Scientists identify new genes that influence how the body regulates blood pressure

Researchers at the University of Georgia have identified several new genes that influence how the body regulates blood pressure. This may help scientists develop novel blood pressure treatments or even allow them to tailor prevention strategies for individuals based on their genes.

19 Dec 2017

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence, recently earned a second phase of grant funding in the amount of $10.8 million for an additional five years.

19 Dec 2017

New study suggests young adulthood as most beneficial age for HIV screening

A new study suggests that the most beneficial age for a one-time screening HIV test of the general population would be age 25.

19 Dec 2017

Researchers use genomics to advance understanding of Parkinson´s disease

It is widely known that genomics has already begun to influence medicine and that bioinformatics holds the key for developing new medical approaches, but how does medical genomics really work?

19 Dec 2017

Pittcon Release eBook Featuring the Latest Scientific Advances

Ahead of the 2018 conference and expo, Pittcon has released an eBook that highlights the latest advances in a range of scientific disciplines. It is an ‘ultimate compilation’ of scientific articles and interviews with some of the worlds leading scientists.

From Pittcon 19 Dec 2017

Mutational patterns could identify breast cancer patients most likely to respond to platinum-based chemotherapy

The presence in advanced breast cancer of mutational signatures characteristic of homologous recombination deficiency (HRD) was associated with improved clinical outcomes to treatment with platinum-based chemotherapy.

19 Dec 2017

New genetic analysis of candidiasis reveals surprising fungal sex secrets

Working together with researchers in the Université Paris-Sud in France and University Medical Centre Göttingen in Germany, ICREA Research Professor Toni Gabaldón and his team at the Centre for Genomic Regulation in Barcelona read the genetic code of 33 separate strains of the yeast Candida glabrata, the second most common cause of candidiasis.

15 Dec 2017

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome.

15 Dec 2017

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas.

15 Dec 2017

Researchers win NIH grants for Alzheimer's research on Amish resilience and rapid onset

Researchers from Case Western Reserve University School of Medicine have received two grant awards, in partnership with investigators from other institutions, from the National Institutes of Health to conduct major studies on Alzheimer's disease, the most common form of memory loss and other forms of dementia in older persons.

14 Dec 2017

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.

14 Dec 2017

Scientists develop new, high resolution method for identifying microbial species and strains

Scientists from the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions New York University and the University of Florida today published a report detailing their new, more accurate method for identifying individual microbial species and strains in a community.

13 Dec 2017

Patient satisfaction, good caregiver communication linked to reduced risk of hospital readmission

A survey of patients admitted to Massachusetts General Hospital (MGH) has found that patients reporting greater levels of satisfaction with their care and good communication with the health care providers were significantly less like to readmitted to the hospital in the 30 days after discharge.

11 Dec 2017

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

A group of the nation's premier cancer researchers led by the Baylor Scott & White Research Institute and the Translational Genomics Research Institute -- has secured a $5.13 million federal grant to develop an early detection system for pancreatic cancer, the nation's third-leading cause of cancer-related death.

11 Dec 2017

Genomic News and Research

Nanobiotix receives FDA approval for first immuno-oncology trial

Scientists discover five new regions of the genome that increase asthma risk

Findings provide better understanding of thyroid hormones' role in mammalian seasonal changes

Gene editing shows promise to help people at risk of hearing loss

Certain brain tumor patients more likely to receive short hospice services, study finds

Study identifies potential markers for early diagnosis, treatment of oral tongue cancer

Scientists identify new genes that influence how the body regulates blood pressure

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

New study suggests young adulthood as most beneficial age for HIV screening

Researchers use genomics to advance understanding of Parkinson´s disease

Pittcon Release eBook Featuring the Latest Scientific Advances

Mutational patterns could identify breast cancer patients most likely to respond to platinum-based chemotherapy

New genetic analysis of candidiasis reveals surprising fungal sex secrets

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers win NIH grants for Alzheimer's research on Amish resilience and rapid onset

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

Scientists develop new, high resolution method for identifying microbial species and strains

Patient satisfaction, good caregiver communication linked to reduced risk of hospital readmission

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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