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Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Melanomas caused by sun exposure have been matched with targeted treatments and immunotherapies, in many cases dramatically extending patients' lives. However, there are other kinds of melanoma not related to sun exposure and because they are caused by different genetic changes, they are not susceptible to the same targeted treatments.

23 Oct 2017

Study shows link between symptom burden and use of health care services in advanced cancer patients

Hospitalized patients with advanced cancer who report more intense and numerous physical and psychological symptoms appear to be at risk for longer hospital stays and unplanned hospital readmissions.

23 Oct 2017

Systematic review finds lack of data on medical cannabis use in children and adolescents

A systematic review of published studies on the use of medical cannabis in children and adolescents finds a notable lack of studies and a minimal number of the randomized, controlled trials needed to confirm the effectiveness of a treatment.

23 Oct 2017

Researchers use nanopore technique to detect biomarkers of disease

Adam Hall, Ph.D., isn't kidding when he says the research he does is on a very small scale. But he is understating things more than just a little.

20 Oct 2017

New CAR-T cell therapy offers effective option for certain blood cancer patients

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis is one of the first centers nationwide to offer a new immunotherapy that targets certain blood cancers.

19 Oct 2017

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

A human gene called p53, which is commonly known as the "guardian of the genome," is widely known to combat the formation and progression of tumors. Yet, mutant forms of p53 have been linked to more cases of human cancer than any other gene.

19 Oct 2017

TGen project to develop standard operating procedures for single-cell RNA sequencing

The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.

17 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

Study uses precision medicine approach to find effective treatments for rare cancers

For the first time, researchers have been able to identify effective treatments for patients with rare cancers by analyzing genes and proteins in their blood and tumors. In a study reported in The Oncologist, half the patients receiving these targeted treatments saw their rare cancers either stabilize, shrink or go into remission.

17 Oct 2017

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions including Colorado State University and Fred Hutchinson Cancer Center reported results today from a glioblastoma study in which they validated a biomarker indicative of a patient's prognosis and likely response to specific therapies.

16 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

A major national effort to expand the reach of cancer immunotherapy to benefit more patients will draw upon the expertise of a team of researchers at The University of Texas MD Anderson Cancer Center.

13 Oct 2017

Researchers find multiple new mutations linked to autism in children but not their parents

Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the child's parents, researchers from the University of Washington School of Medicine report.

12 Oct 2017

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link.

12 Oct 2017

Whole genome sequencing could help better understand genetic abnormalities underlying autism

An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.Autism has genetic roots, but most cases can't be explained by current genetic tests.

12 Oct 2017

Existing drugs could help patients with rare form of bone cancer

Patients with a rare bone cancer of the skull and spine - chordoma - could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

12 Oct 2017

C-section kids could be at greater risk of being overweight due to differences in their gut bacteria

Researchers from NYU School of Medicine studied the effects of Caesarean section on the weights of the offspring in laboratory mice and found that they are more at risk of becoming overweight and obese.

12 Oct 2017

New genomics study aims to evaluate effectiveness of blood test in detecting breast cancer

Cancer researchers at Intermountain Medical Center and the Intermountain Precision Genomics Program in Salt Lake City are launching an exciting, new three-year study to determine if a blood test that looks for DNA from a cancer tumor can be used to complement mammography to improve the way breast cancer is diagnosed.

11 Oct 2017

Survey highlights major gap in women’s knowledge about genomic testing in breast cancer

Breast cancer is the most feared type of cancer among women in Germany, according to a recent representative survey commissioned by Agendia, a world leader in personalized medicine and molecular cancer diagnostics.

11 Oct 2017

Genomic News and Research

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Study shows link between symptom burden and use of health care services in advanced cancer patients

Systematic review finds lack of data on medical cannabis use in children and adolescents

Researchers use nanopore technique to detect biomarkers of disease

New CAR-T cell therapy offers effective option for certain blood cancer patients

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

TGen project to develop standard operating procedures for single-cell RNA sequencing

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

Study uses precision medicine approach to find effective treatments for rare cancers

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Study helps understand basic mechanisms of mitochondrial DNA maintenance

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

Researchers find multiple new mutations linked to autism in children but not their parents

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

Whole genome sequencing could help better understand genetic abnormalities underlying autism

Existing drugs could help patients with rare form of bone cancer

C-section kids could be at greater risk of being overweight due to differences in their gut bacteria

New genomics study aims to evaluate effectiveness of blood test in detecting breast cancer

Survey highlights major gap in women’s knowledge about genomic testing in breast cancer

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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