Genomic News and Research

RSS

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions including Colorado State University and Fred Hutchinson Cancer Center reported results today from a glioblastoma study in which they validated a biomarker indicative of a patient's prognosis and likely response to specific therapies.

16 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

A major national effort to expand the reach of cancer immunotherapy to benefit more patients will draw upon the expertise of a team of researchers at The University of Texas MD Anderson Cancer Center.

13 Oct 2017

Researchers find multiple new mutations linked to autism in children but not their parents

Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the child's parents, researchers from the University of Washington School of Medicine report.

12 Oct 2017

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link.

12 Oct 2017

Whole genome sequencing could help better understand genetic abnormalities underlying autism

An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.Autism has genetic roots, but most cases can't be explained by current genetic tests.

12 Oct 2017

Existing drugs could help patients with rare form of bone cancer

Patients with a rare bone cancer of the skull and spine - chordoma - could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

12 Oct 2017

C-section kids could be at greater risk of being overweight due to differences in their gut bacteria

Researchers from NYU School of Medicine studied the effects of Caesarean section on the weights of the offspring in laboratory mice and found that they are more at risk of becoming overweight and obese.

12 Oct 2017

New genomics study aims to evaluate effectiveness of blood test in detecting breast cancer

Cancer researchers at Intermountain Medical Center and the Intermountain Precision Genomics Program in Salt Lake City are launching an exciting, new three-year study to determine if a blood test that looks for DNA from a cancer tumor can be used to complement mammography to improve the way breast cancer is diagnosed.

11 Oct 2017

Survey highlights major gap in women’s knowledge about genomic testing in breast cancer

Breast cancer is the most feared type of cancer among women in Germany, according to a recent representative survey commissioned by Agendia, a world leader in personalized medicine and molecular cancer diagnostics.

11 Oct 2017

Genetic discovery provides strong lead for future research on male contraception

When it comes to birth control, many males turn to two options: condoms or vasectomies. While the two choices are effective, both methods merely focus on blocking the transportation of sperm.

10 Oct 2017

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Hui Feng, MD, PhD, assistant professor of pharmacology and medicine at Boston University School of Medicine, is the recipient of a four-year, $792,000 grant from the American Cancer Society to study why T-cell acute lymphoblastic leukemia (T-ALL) is so aggressive and resistant to treatment.

10 Oct 2017

Five new ways individualized medicine has moved from research lab into clinical care

Advancements in individualized medicine are offering health care providers new tools to quickly and accurately diagnose, treat, predict and, eventually, prevent disease. Keith Stewart, M.B., Ch.B., Carlson and Nelson Endowed Director, Mayo Clinic Center for Individualized Medicine, today outlined five new ways individualized medicine has moved from the research lab into clinical care. Dr. Stewart made his statements during the opening of the 2017 "Individualizing Medicine Conference: Advancing Care Through Genomics" in Rochester.

9 Oct 2017

Researchers discover mutation that amplifies capabilities of tumor-suppressor protein

Cancer researchers have long hailed p53, a tumor-suppressor protein, for its ability to keep unruly cells from forming tumors. But for such a highly studied protein, p53 has hidden its tactics well.

9 Oct 2017

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

9 Oct 2017

Patients with documented penicillin allergy more likely to develop surgical site infections, study finds

A study by Massachusetts General Hospital investigators found that surgical patients believed to be allergic to penicillin were significantly more likely to develop surgical site infections than were patients with no documented allergy, a difference totally attributable to the alternative antibiotics used to prevent such infections.

9 Oct 2017

Whitehead Institute scientists identify brain/body connection in genomic region linked to autism

For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes--fam57ba and doc2a--in zebrafish and certain brain and body traits, such as seizures, hyperactivity, enlarged head size, and obesity.

9 Oct 2017

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery.

6 Oct 2017

Study uncovers differences in bacterial composition of healthy vs. cancerous breast tissue

In a newly published study, Cleveland Clinic researchers have uncovered differences in the bacterial composition of breast tissue of healthy women vs. women with breast cancer.

6 Oct 2017

JAX professor receives $2.8 million New Innovator Award for skin microbiome research

Julia Oh, Ph.D., a Jackson Laboratory (JAX) assistant professor who explores the communities of microorganisms that live on the human skin, has received a special New Innovator Award of $2,835,000 from the National Institutes of Health (NIH) to explore how to develop engineered probiotic treatments for a variety of skin and infectious diseases.

5 Oct 2017

Genomic News and Research

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Study helps understand basic mechanisms of mitochondrial DNA maintenance

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

Researchers find multiple new mutations linked to autism in children but not their parents

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

Whole genome sequencing could help better understand genetic abnormalities underlying autism

Existing drugs could help patients with rare form of bone cancer

C-section kids could be at greater risk of being overweight due to differences in their gut bacteria

New genomics study aims to evaluate effectiveness of blood test in detecting breast cancer

Survey highlights major gap in women’s knowledge about genomic testing in breast cancer

Genetic discovery provides strong lead for future research on male contraception

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Five new ways individualized medicine has moved from research lab into clinical care

Researchers discover mutation that amplifies capabilities of tumor-suppressor protein

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

Patients with documented penicillin allergy more likely to develop surgical site infections, study finds

Whitehead Institute scientists identify brain/body connection in genomic region linked to autism

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Study uncovers differences in bacterial composition of healthy vs. cancerous breast tissue

JAX professor receives $2.8 million New Innovator Award for skin microbiome research

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News