Genomic News and Research

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Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma.

10 May 2017

Studies pave way for genome-targeted treatments in pancreatic cancer

University of Pittsburgh and UPMC researchers are paving the way for genome-targeted treatments in pancreatic cancer, an especially deadly form of cancer with few existing therapeutic options, according to a pair of recent studies.

9 May 2017

New conference aims to improve understanding of how advances in genomics influence society

From prenatal genetic screening to the genetic testing of women with family histories of breast cancer, genomics is rapidly becoming a fixture in our lives.

5 May 2017

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

International consensus addresses research bottlenecks to diagnose rare genetic diseases

A worldwide consensus co-authored by more than 40 scientists sets out ways to address research bottlenecks as the international community strives to diagnose most rare genetic diseases by 2020.

4 May 2017

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

A team of Florida State University researchers is using mathematical modeling to find the best and most effective chemotherapy treatments for cancer patients.

4 May 2017

New imaging techniques at Mayo Clinic reveal tumor firmness, adhesion before brain cancer surgery

It's not often that a fall saves someone's life. Helen Powell, 74, says that was the case for her. A computerized tomography scan that followed her fall revealed a cancerous brain tumor that led her to Mayo Clinic and surgery using first-in-the-world technology.

4 May 2017

Lethal DNA re-replication may be used to attack cancer cells

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' (alterations to the structure, composition and/or number of chromosomes), and this process gives rise to aberrant cells as those detected in many carcinomas.

4 May 2017

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

10x Genomics, a company focused on enabling the mastery of biology by accelerating genomic discovery, today announced publication of an article in the journal Nature of a collaborative research study with researchers at the Stanford University School of Medicine.

From 10x Genomics, Inc. 4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Study finds no link between gluten intake and heart disease risk in people without celiac disease

A study of more than 100,000 men and women revealed that dietary gluten is not associated with heart disease risk in people without celiac disease. The findings also suggest that limiting whole grains as part of a low-gluten diet may increase the risk of heart disease in people who do not have celiac disease.

3 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Nonalcoholic fatty liver disease (NAFLD) - a condition that can lead to liver cirrhosis and cancer -; isn't typically detected until it's well advanced. Even then, diagnosis requires an invasive liver biopsy.

2 May 2017

Study describes new targets for precision treatment of meningiomas

Winner of the Integra Foundation Award, Mark W. Youngblood, presented his research, Clinical and Molecular Features of Genomic Subgroups in Meningioma, during the 2017 American Association of Neurological Surgeons Annual Scientific Meeting.

29 Apr 2017

Study sheds new light on evolutionary origin of the vertebrate brain

A study recently published in PLOS Biology provides information that substantially changes the prevailing idea about the brain formation process in vertebrates and sheds some light on how it might have evolved.

28 Apr 2017

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

A new $2.4-million program for graduate students seeking to contribute to breakthrough discoveries in medicine and biology has been established at Penn State University with nearly $1.4 million in funding from the National Library of Medicine of the U.S. National Institutes of Health and more than $1 million from Penn State.

28 Apr 2017

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation today announced its largest research commitment ever -- $4 million in collaborative grants -- most from its new Accelerator Grants program to study neuroendocrine tumors, a widely misunderstood, commonly misdiagnosed cancer type, without adequately identified genomic drivers.

27 Apr 2017

AI key to driving precision medicine in cancer?

It is worth noting that in the U.S. and in many countries, digital pathology is still at a very early stage, compared to many other fields that were digitized 15 or 20 years ago such as radiology. There have been some barriers to the adoption of digital pathology such as regulatory challenges that are only just now being overcome. Recently, the FDA approved the use of whole slide imaging software for primary diagnostics.

27 Apr 2017

Genomic News and Research

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

Studies pave way for genome-targeted treatments in pancreatic cancer

New conference aims to improve understanding of how advances in genomics influence society

Genetic study outlines path to personalize breast cancer risk assessment and treatment

International consensus addresses research bottlenecks to diagnose rare genetic diseases

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

New imaging techniques at Mayo Clinic reveal tumor firmness, adhesion before brain cancer surgery

Lethal DNA re-replication may be used to attack cancer cells

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

New research uncovers role of mysterious molecule in skin cancer

Scientists map genetic changes that help drive aggressive brain tumor

Study finds no link between gluten intake and heart disease risk in people without celiac disease

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Study describes new targets for precision treatment of meningiomas

Study sheds new light on evolutionary origin of the vertebrate brain

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

AI key to driving precision medicine in cancer?

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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