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Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.

21 Sep 2016

Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers

The Wellcome Trust Sanger Institute is combining the power of COSMIC, its large-scale cancer genetics database, with ProteinPaint data mining and visualization system at St. Jude Children’s Research Hospital in Memphis TN, to support the discovery and understanding of genetic mutations in paediatric cancers.

21 Sep 2016

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene expression during cell division.

20 Sep 2016

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

An international team of researchers who discovered a new gene disorder that causes severe childhood epilepsy leveraged that finding to reduce seizures in two children.

20 Sep 2016

Scientists begin research work at new £650 million Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs.

20 Sep 2016

New less invasive method could detect bacterial infection in young febrile infants

Physicians from Children's Hospital of Michigan, Wayne State University, UC Davis Medical Center and Nationwide Children's Hospital, in collaboration with 19 other pediatric emergency departments around the country, have established a "proof of principle" for measuring patterns of ribonucleic acid (RNA) expression in the bloodstream that can enable clinicians to distinguish bacterial infections from other causes of fever in infants up to two months old.

19 Sep 2016

Research seeks to improve nutritional and milling quality of new oat varieties

Most of the oats American milling companies use comes from Canada—that's something South Dakota State University oats breeder Melanie Caffé-Treml wants to change. Her research seeks to increase the quality of locally-grown oats.

15 Sep 2016

UNSW set to become home to world’s first pre-production prototype of high resolution microscope

Cancer researchers in NSW will now have access to a range of cutting edge technology, including a world-first super-resolution microscope at UNSW, thanks a $4 million investment by the Cancer Institute NSW.

13 Sep 2016

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass.

9 Sep 2016

Liquid biopsies may be effective option for detecting mutations in advanced lung cancer patients

For patients with advanced lung cancer, a non-invasive liquid biopsy may be a more effective and suitable alternative to the gold standard tissue biopsy to detect clinically relevant mutations and help guide their course of treatment, suggests a new study published this week in the journal Clinical Cancer Research from researchers at the Abramson Cancer Center at the University of Pennsylvania.

9 Sep 2016

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Scientists discover potential new genetic causes for intellectual disability

An international group of researchers has for the first time identified a set of 30 inherited recessive genes that play a role in intellectual disability (ID), a neurodevelopmental disorder that, according to the Centers for Disease Control, affects as many as 213 million people around the world.

9 Sep 2016

Tgen-NAU researchers produce anthrax genome sequence from victims of 1979 outbreak

A new study by the Translational Genomics Research Institute and Northern Arizona University used deep DNA sequencing methods to generate the anthrax genome sequence from the victims of the 1979 anthrax outbreak in Sverdlovsk, Russia, when it was part of the USSR.

9 Sep 2016

New blood test helps identify bacterial infection in infants with fever

A blood test used to measure patterns of ribonucleic acid (RNA) expression can help determine if fever in infants under 2 months old is caused by bacterial or viral infection, according to a preliminary study recently published in the Journal of the American Medical Association.

8 Sep 2016

New molecular mechanism may explain pain relieving drug’s diverse benefits

Aspirin's ability to reduce the risk of both cardiovascular disease and colon cancer has been a welcome, yet puzzling, attribute of the pain reliever that has been a mainstay in medicine cabinets for more than 100 years.

7 Sep 2016

New computer program can predict underlying genomics of ER+ breast cancer

The number of tubules in tumors may predict which women with estrogen receptor positive (ER+) breast cancer will benefit from hormone therapy alone and which require chemotherapy, researchers at Case Western Reserve University have found.

7 Sep 2016

Researchers find genomic material from Zika virus in tears

Researchers have found that Zika virus can live in eyes and have identified genetic material from the virus in tears, according to a study from Washington University School of Medicine in St. Louis.

7 Sep 2016

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

Obesity almost always increases cancer risk and worsens outcomes, but researchers led by scientists at Dana-Farber Cancer Institute report that overweight patients with advanced kidney cancer had significantly longer survival than those who were normal or underweight.

6 Sep 2016

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

5 Sep 2016

New study details design and validation of accurate screening test for detecting deadly HAIs

A new study by the Translational Genomics Research Institute details the design and validation of a low-cost, rapid and highly accurate screening tool -- known as KlebSeq -- for potentially deadly healthcare-acquired infections (HAIs), such as Klebsiella pneumoniae.

2 Sep 2016

Genomic News and Research

Duke researchers discover blood markers linked to drug-resistant tumor cells

Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

Scientists begin research work at new £650 million Francis Crick Institute building

New less invasive method could detect bacterial infection in young febrile infants

Research seeks to improve nutritional and milling quality of new oat varieties

UNSW set to become home to world’s first pre-production prototype of high resolution microscope

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Liquid biopsies may be effective option for detecting mutations in advanced lung cancer patients

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists discover potential new genetic causes for intellectual disability

Tgen-NAU researchers produce anthrax genome sequence from victims of 1979 outbreak

New blood test helps identify bacterial infection in infants with fever

New molecular mechanism may explain pain relieving drug’s diverse benefits

New computer program can predict underlying genomics of ER+ breast cancer

Researchers find genomic material from Zika virus in tears

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

New study details design and validation of accurate screening test for detecting deadly HAIs

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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