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ELSIP: Integrating personalized medicine into clinical practice

Lynn G. Dressler Dr. P.H. Director, Personalized Medicine and Pharmacogenomics, Mission Health, Fullerton Genetics Center will present: Addressing the Ethical, Legal, Social and Policy Issues Related to Integrating Personalized Medicine into Routine Clinical Care at the 5th Annual Personalized Medicine Conference in Boston, MA on October 21- 22, 2013.

11 Jul 2013

New method to identify pathogenic strains that cause pneumonia

Researchers from Boston University School of Medicine (BUSM) and George Washington University (GWU) have developed a method to rapidly identify pathogenic species and strains causing illnesses, such as pneumonia, that could help lead to earlier detection of disease outbreaks and pinpoint effective treatments more quickly.

11 Jul 2013

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

10 Jul 2013

Boehringer Ingelheim signs multi-year renewal agreement to NextBio Research Platform

NextBio, whose Big Data technology enables users to apply genomic data from disparate sources in novel and useful ways across life sciences research, today announced that Boehringer Ingelheim has signed a multi-year renewal agreement to the NextBio Research Platform.

9 Jul 2013

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

9 Jul 2013

Mouse study identifies new treatment options for bowel cancer

Researchers have discovered the genetic processes that cause specific types of bowel cancer. Using this knowledge, they identified cancer drugs that target these genes. Their findings offer the opportunity to develop personalised treatment based on a person's genetic profile.

9 Jul 2013

BioNano Genomics signs strategic partnership with New York Genome Center

BioNano Genomics and the New York Genome Center announced today a strategic partnership between the two institutions that includes the purchase of an Irys System by NYGC.

8 Jul 2013

Epigenome mapping uncovers unique patterns that emerge during generation of brain circuitry

High-resolution mapping of the epigenome has discovered unique patterns that emerge during the generation of brain circuitry in childhood.

6 Jul 2013

Findings uncover epigenomic modification that occurs during brain formation

Changes in the epigenome, including chemical modifications of DNA, can act as an extra layer of information in the genome, and are thought to play a role in learning and memory, as well as in age-related cognitive decline.

5 Jul 2013

Study identifies genomic regions associated with cholera susceptibility

An international research team has used a novel approach to identify genetic factors that appear to influence susceptibility to cholera. The findings by investigators from Massachusetts General Hospital (MGH), the Broad Institute and the International Center for Diarrh-al Disease Research, Bangladesh (ICDDR,B) indicate the importance of pathways involved in regulating water loss in intestinal cells and of the innate immune system in the body's response to the bacteria that causes cholera, which affects from 3 to 5 million people each year and causes more than 100,000 deaths.

4 Jul 2013

Duke researchers solve some mysteries related to the use of aspirin

Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some people benefit and others don't.

4 Jul 2013

Study shows miR-22 plays a key role in breast and blood cancers

A mere 25 years ago, noncoding RNAs were considered nothing more than "background noise" in the overall genomic landscape. Now, two new studies reveal that one of these tiny noncoding molecules - microRNA-22 - plays an outsized role in two types of cancer.

4 Jul 2013

Scientists discover network for molecular communication in human embryonic stem cells

Scientists at A*STAR's Genome Institute of Singapore (GIS) and the Max Planck Institute for Molecular Genetics (MPIMG) in Berlin (Germany) have discovered a molecular network in human embryonic stem cells (hESCs) that integrates cell communication signals to keep the cell in its stem cell state.

3 Jul 2013

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Yale Cancer Center scientists, together with colleagues at the Denver Police Crime Lab and the University of Colorado, have found evidence that a human metastatic tumor can arise when a leukocyte (white blood cell) and a cancer cell fuse to form a genetic hybrid.

3 Jul 2013

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Scientists found genetic variations that could be used to identify women who are most likely to benefit from a certain type of breast cancer prevention drug—and who should avoid it.

3 Jul 2013

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that the TransATAC clinical validation study for its Prosigna Breast Cancer Prognostic Gene Signature Assay, which is based on the PAM50 gene signature, was published in the Journal of Clinical Oncology.

From NanoString Technologies 2 Jul 2013

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

The Case Comprehensive Cancer Center (CCCC) again demonstrated the compelling power of partnership in securing an overall rating of "outstanding" and a five-year renewal of its grant from the National Cancer Institute (NCI).

28 Jun 2013

Chromosomal deletion associated with changes in brain's white matter and delays language acquisition

A chromosomal deletion is associated with changes in the brain's white matter and delayed language acquisition in youngsters from Southeast Asia or with ancestral connections to the region, said an international consortium led by researchers at Baylor College of Medicine.

28 Jun 2013

RUCDR Infinite Biologics receives $44.5 million Cooperative Agreement award from NIMH centre

RUCDR Infinite Biologics, the world's largest university-based biorepository, received a $44.5 million Cooperative Agreement award from the National Institute of Mental Health earlier this month to support its NIMH Center for Collaborative Genomics Research on Mental Disorders, which provides services to NIMH-funded scientists engaged in genomic research on mental disorders.

28 Jun 2013

UNIGE researchers identify genomic variations associated with trisomy 21

Down syndrome, more commonly known as "trisomy 21" is very often accompanied by pathologies found in the general population: Alzheimer's disease, leukemia, or cardiac deficiency.

28 Jun 2013

Genomic News and Research

ELSIP: Integrating personalized medicine into clinical practice

New method to identify pathogenic strains that cause pneumonia

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Boehringer Ingelheim signs multi-year renewal agreement to NextBio Research Platform

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

Mouse study identifies new treatment options for bowel cancer

BioNano Genomics signs strategic partnership with New York Genome Center

Epigenome mapping uncovers unique patterns that emerge during generation of brain circuitry

Findings uncover epigenomic modification that occurs during brain formation

Study identifies genomic regions associated with cholera susceptibility

Duke researchers solve some mysteries related to the use of aspirin

Study shows miR-22 plays a key role in breast and blood cancers

Scientists discover network for molecular communication in human embryonic stem cells

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

Chromosomal deletion associated with changes in brain's white matter and delays language acquisition

RUCDR Infinite Biologics receives $44.5 million Cooperative Agreement award from NIMH centre

UNIGE researchers identify genomic variations associated with trisomy 21

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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