Genomic News and Research

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Definitive multiple sclerosis linkage screen

A cluster of genes on chromosome six is the only one that plays a significant role in multiple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 130th annual meeting of the American Neurological Association in San Diego.

22 Sep 2005

Manic depression linked to two chromosomal regions in the human genome

An international team of 53 researchers has offered the most convincing evidence so far linking bipolar disorder, also known as manic depression, to two chromosomal regions in the human genome. The finding gives scientists refined targets for further gene studies.

19 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

The findings do not limit the utility of the cells for some types of research or for some future clinical applications, the researchers say, but draw attention to the need to closely monitor stem cell lines for genetic changes and to study how these alterations affect the cells' behavior.

6 Sep 2005

Significant new breakthroughs in understanding how the genes in mammals are controlled

An international consortium of genome research institutes and investigators, including Jackson Laboratory Staff Scientists Carol J. Bult, Ph.D., and Martin Ringwald, Ph.D., has reported significant new breakthroughs in understanding how the genes in mammals are controlled.

6 Sep 2005

Patent for determining gene function quickly with Hellsgate

A CSIRO innovation for determining gene function quickly and with virtually 100 per cent efficiency has been granted a US patent clarifying its leadership position in the international gene silencing arena.

6 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

5 Sep 2005

New understanding of how our genome works to produce a complex organism like a human being

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

4 Sep 2005

Study provides first steps toward individualized treatment of serious injuries

A multi-institutional research collaborative has begun to decipher the complex interplay of genes that underlies the body's response to major injuries.

1 Sep 2005

More than 15 percent of our genes are mobilized to defend against microbial attacks

The body's overwhelming genetic defense, which has implications for the survival of patients who are severely burned or injured, was revealed in a sweeping analysis of gene activity in volunteers who were injected with a bacterial product that temporarily created flu-like symptoms.

1 Sep 2005

When it comes to inflammation, too much of a good thing can be deadly

In some severely injured patients, this normal healing process can develop into a lethal, whole-body response, including bloodstream infection (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious, so doctors can't accurately predict how each injured patient will fare.

31 Aug 2005

Discovery of a potential oncogene in ovarian cancer

Researchers at The University of Texas M. D. Anderson Cancer Center report they have discovered a potential oncogene in ovarian cancer, which is the leading cause of gynecological cancer death in U.S. women.

22 Aug 2005

Preliminary molecular diagram of the early stages of embryo formation

A team of genomic researchers headed by biologists at New York University's Center for Comparative Functional Genomics, in collaboration with researchers at Harvard University, the Max Planck Institute, and Cenix Biosciences, has mapped out a preliminary molecular diagram of the early stages of embryo formation, offering for the first time a global look at how a single cell begins its path into a multi-cellular organism.

11 Aug 2005

First large-scale effort to sequence the flu genome

Multiple strains of the flu virus, circulating in a population at the same time, can reshuffle their genes and create a new virus, one capable of infecting many more people, according to a new study in the open-access journal PLoS Biology.

26 Jul 2005

More efficient genome-mining technique

An innovative new statistical method, described in the open-access journal PLoS Biology, streamlines the computation required to identify all the potential locations in the genome that influence a particular physical trait, or phenotype.

26 Jul 2005

Multi-species genome comparison sheds new light on evolutionary processes

An international team that includes researchers from the National Human Genome Research Institute (NHGRI) has discovered that mammalian chromosomes have evolved by breaking at specific sites rather than randomly as long thought - and that many of the breakage hotspots are also involved in human cancer.

25 Jul 2005

Discovery of a receptor that appears to function as one "lock" that HSV opens to allow it to enter human cells

It's one of the most common viruses in America, and one that causes the most guilt and shame. It can get inside almost any kind of human cell, reproduce in vast numbers, and linger for years in the body, causing everything from recurrent genital blisters to sores around the mouth. Its complications can kill, and it may increase susceptibility to many nerve and brain disorders.

24 Jul 2005

Genomic News and Research

Definitive multiple sclerosis linkage screen

Manic depression linked to two chromosomal regions in the human genome

Nuclear receptor proteins could change anti-inflammatory treatments

Human embryonic stem cell lines accumulate changes in their genetic material over time

Significant new breakthroughs in understanding how the genes in mammals are controlled

Patent for determining gene function quickly with Hellsgate

Human embryonic stem cell lines accumulate changes in their genetic material over time

New understanding of how our genome works to produce a complex organism like a human being

Study provides first steps toward individualized treatment of serious injuries

More than 15 percent of our genes are mobilized to defend against microbial attacks

When it comes to inflammation, too much of a good thing can be deadly

Discovery of a potential oncogene in ovarian cancer

Preliminary molecular diagram of the early stages of embryo formation

First large-scale effort to sequence the flu genome

More efficient genome-mining technique

Multi-species genome comparison sheds new light on evolutionary processes

Discovery of a receptor that appears to function as one "lock" that HSV opens to allow it to enter human cells

Hidden secrets on the nature and timing of genome evolution in mammals revealed

SIRT1 gene suppresses longevity

Genome studies may help target new drugs to fight them

Genetics & Genomics eBook

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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