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Scientists use next-generation protein degradation technology to study CTCF's role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital used a next-generation protein degradation technology to study CTCF.

26 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

Genomic screening can facilitate early detection of thyroid cancer in patients with RET gene variants

Population-based genomic screening can facilitate early detection of medullary thyroid cancer (MTC) in patients with variants in the RET gene, a new Geisinger study found.

25 Jan 2023

Deaf patients break barriers by co-designing their own care with University of Utah Health

Navigating health care is hard enough when English is your first language-;imagine the difficulty when American Sign is your first language.

25 Jan 2023

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

25 Jan 2023

A slight increase in Mpox cases across the globe, along with an increase in deaths

The WHO discusses genomic sequencing of the Mpox virus, in addition to providing public and clinical health links between HIV and Mpox.

24 Jan 2023

Study shows spatial organization in tumor cells

Researchers investigated whether the observed tumor cellular heterogeneity and architecture result from stochastic and chaotic events, or whether there is more coordination in the histopathological chaos of cancer.

24 Jan 2023

Researchers identify a key host-cell player in COVID-19 infections

Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.

24 Jan 2023

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work – until now.

23 Jan 2023

WHO’s 14th situation report for the multi-country outbreak of mpox overviews the clinical and public health links between HIV and mpox

In the present report, researchers reported the most recent findings of MPXV infections.

23 Jan 2023

Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi

Researchers conducted a serosurvey during the SARS-CoV-2 Omicron wave in Malawi.

23 Jan 2023

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

Researchers performed an in silico analysis to estimate the relative risks of recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

23 Jan 2023

Researchers estimate COVID-19 Omicron variant mortality in Denmark

A recent Eurosurveillance study investigated how coincidental infections influenced COVID-19 mortality estimates after the emergence of the Omicron variant.

23 Jan 2023

First known epidemic of highly pathogenic avian influenza H5N1 in farmed mink

Highly pathogenic avian influenza (HPAI) A(H5N1) is a strain of the avian influenza virus that primarily affects birds, particularly poultry. HPAI A(H5N1) is a highly contagious and deadly virus that can cause severe illness and death in birds, including chickens, ducks, geese, and turkeys.

22 Jan 2023

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

20 Jan 2023

Addition of nab-paclitaxel to gemcitabine/cisplatin does not improve overall survival of patients with advanced biliary tract cancers

Adding nab-paclitaxel to a standard treatment of gemcitabine plus cisplatin does not significantly extend median overall survival (OS) time for patients with advanced biliary tract cancers, although it may provide a benefit for subsets of patients with locally advanced disease or gallbladder adenocarcinoma.

20 Jan 2023

Study sheds light on the mechanisms behind virulence of MRSA blood stream infections

Researchers at Mount Sinai, in collaboration with researchers at New York University, have published a study in Cell Host and Microbe that sheds light on the mechanisms behind the severity, or virulence, of methicillin-resistant Staphylococcus aureus (MRSA) blood stream infections.

20 Jan 2023

UK set to boost genomics expertise through a landmark partnership with Thailand

UK patients will benefit from a new partnership with Thailand to share expertise of genome sequencing, collaborate in research, education and training opportunities, knowledge exchange and genomics data handling.

20 Jan 2023

How effective are prior SARS-CoV-2 infections and hybrid immunity against Omicron breakthrough infections?

Researchers performed a systematic review and meta-regression study to determine the breadth and duration of the protective immunity conferred by previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hybrid immunity.

20 Jan 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Genomic News and Research

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Genomic screening can facilitate early detection of thyroid cancer in patients with RET gene variants

Deaf patients break barriers by co-designing their own care with University of Utah Health

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

A slight increase in Mpox cases across the globe, along with an increase in deaths

Study shows spatial organization in tumor cells

Researchers identify a key host-cell player in COVID-19 infections

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

WHO’s 14th situation report for the multi-country outbreak of mpox overviews the clinical and public health links between HIV and mpox

Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

Researchers estimate COVID-19 Omicron variant mortality in Denmark

First known epidemic of highly pathogenic avian influenza H5N1 in farmed mink

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

Addition of nab-paclitaxel to gemcitabine/cisplatin does not improve overall survival of patients with advanced biliary tract cancers

Study sheds light on the mechanisms behind virulence of MRSA blood stream infections

UK set to boost genomics expertise through a landmark partnership with Thailand

How effective are prior SARS-CoV-2 infections and hybrid immunity against Omicron breakthrough infections?

Researchers create the first 'living medicine' to treat drug-resistant lung infections

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