Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Schizophrenia brain marker matches genetic risk

Polygenic risk for schizophrenia correlates with neural inefficiency in the left dorsolateral prefrontal cortex, say researchers.

24 Dec 2013

Changes to LZTR1 gene predispose people to develop schwannomas

Changes to a gene called LZTR1 predispose people to develop a rare disorder where multiple tumors called schwannomas form near nerve pathways, according to a study published today in the journal Nature Genetics and led by researchers from the University of Alabama at Birmingham.

24 Dec 2013

ORIX USA Health partners with TGen and TD2 to support Arizona's biomedical economy

ORIX USA Health and Life Sciences has completed an investment into Translational Drug Development (TD2) through the purchase of equity from the Translational Genomics Research Institute (TGen).

20 Dec 2013

TGen, Nemucore, and Barrow collaboration aims for new drugs to treat glioblastoma

The Ben & Catherine Ivy Foundation today announced a $3 million grant to the Translational Genomics Research Institute (TGen), Nemucore Medical Innovations Inc., and Barrow Neurological Institute at St. Joseph's Hospital and Medical Center to help fund significant brain tumor research in Arizona.

18 Dec 2013

UCD Conway Institute researchers identify potential biomarker of idiopathic pulmonary ﬁbrosis

Researchers in UCD Conway Institute have identified a potential biomarker of rapidly progressive pulmonary fibrosis and pinpointed a defective molecular function as a potential therapeutic target.

18 Dec 2013

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Investigators at The Feinstein Institute for Medical Research have discovered for the first time, direct evidence of a genetic overlap between schizophrenia and general cognitive ability. The findings are published online in Molecular Psychiatry.

17 Dec 2013

Eurofins Medigenomix, Orion Diagnostica Oy sign co-exclusive technology license agreement

Eurofins Medigenomix, a part of the Eurofins Genomics Business line of Eurofins Scientific and Orion Diagnostica Oy, an in vitro diagnostics company specialising in the development, production and sales of diagnostic test systems, announced that they have signed a co-exclusive technology license agreement. Orion Diagnostic Oy owns the global rights for the SIBA- isothermal nucleic acid detection technology in all fields.

17 Dec 2013

PAM50 FDA-cleared breast cancer test to be launched at ARUP Laboratories

The PAM50 breast cancer signature developed at the University of Utah and Huntsman Cancer Institute received FDA approval and will launch at ARUP Laboratories in Salt Lake City. The test utilizes gene expression data from 50 genes weighted together with clinical variables to generate a risk category and numerical score to assess a patient's risk of distant recurrence at ten years in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), Hormone Receptor-Positive (HR+) breast cancer.

16 Dec 2013

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

New research from University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.

13 Dec 2013

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

A research team from The University of Nottingham has helped uncover a second rare genetic mutation which strongly increases the risk of Alzheimer's disease in later life.

13 Dec 2013

Novel ISM strategy enables selection of potentially effective cancer therapies for patients

A new individualized systems medicine strategy, developed at the Institute for Molecular Medicine Finland FIMM and the Helsinki University Central Hospital, enables a selection of potentially effective cancer therapies for individual patients. The promising results achieved by applying this strategy to chemoresistant adult acute myeloid leukemia patients have been recently published in the Cancer Discovery journal.

13 Dec 2013

Boys who grow up in two-parent homes less likely to have high blood pressure as adults

In a study of African-American men, researchers from the National Institutes of Health found that boys who grew up in two-parent homes were less likely to have high blood pressure as adults compared to those raised by a single parent. Reported in the Dec. 12, 2013, issue of the journal Hypertension, this is the first study of an African-American population to document an association between childhood family living arrangements and blood pressure.

13 Dec 2013

Mitochondrial enzyme SIRT5 regulates proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation.

12 Dec 2013

New strategy for fighting infection targets patient's cells rather than invading pathogens

As more reports appear of a grim "post-antibiotic era" ushered in by the rise of drug-resistant bacteria, a new strategy for fighting infection is emerging that targets a patient's cells rather than those of the invading pathogens.

12 Dec 2013

Tumor-infiltrating lymphocytes may be good biomarker of response to trastuzumab in breast cancer

Women with HER2-positive breast cancer who had the highest levels of immune cells in their tumors gained the most benefit from presurgery treatment with chemotherapy and trastuzumab, according to results presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

12 Dec 2013

New study may pave way for more effective treatment for deadly childhood cancer

A new study by Canadian researchers may pave the way for more effective treatment of an aggressive and deadly type of brain tumour, known as ETMR/ETANTR. The tumour, which is seen only in children under four, is almost always fatal, despite aggressive treatment. The study proposes a new model for how this brain tumour develops and suggests possible targets to investigate for novel therapies.

12 Dec 2013

Budget cuts, years-long flat funding can delay research into effective treatments for cancer

Research advances that have come to fruition over the past year demonstrate extraordinary progress in the fight against cancer, according to a new report released today by the American Society of Clinical Oncology. The report stresses, however, that recent budget cuts and years-long flat funding can only delay efforts to translate research into effective treatments for millions of individuals with cancer.

11 Dec 2013

Broad Medical Research Program, Crohn's & Colitis Foundation of America to merge together

The Broad Medical Research Program, which funds innovative early-stage research into inflammatory bowel disease, will merge with the Crohn's & Colitis Foundation of America, the two organizations announced today.

11 Dec 2013

Nanostring Technologies announces nationwide availability of Prosigna Breast Cancer Assay in 2014

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced nationwide availability of the Prosigna™ Breast Cancer Prognostic Gene Signature Assay beginning in the first quarter of 2014.

From NanoString Technologies 11 Dec 2013

New research project to genetically discriminate "identical" monozygotic twins

Eurofins Scientific, a European leader in Genomics Services, Forensics and Paternity Testing, announces a milestone in genetic and forensic research.

10 Dec 2013

Genomics News and Research

Further Reading

Schizophrenia brain marker matches genetic risk

Changes to LZTR1 gene predispose people to develop schwannomas

ORIX USA Health partners with TGen and TD2 to support Arizona's biomedical economy

TGen, Nemucore, and Barrow collaboration aims for new drugs to treat glioblastoma

UCD Conway Institute researchers identify potential biomarker of idiopathic pulmonary ﬁbrosis

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Eurofins Medigenomix, Orion Diagnostica Oy sign co-exclusive technology license agreement

PAM50 FDA-cleared breast cancer test to be launched at ARUP Laboratories

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

Novel ISM strategy enables selection of potentially effective cancer therapies for patients

Boys who grow up in two-parent homes less likely to have high blood pressure as adults

Mitochondrial enzyme SIRT5 regulates proteins involved in metabolism

New strategy for fighting infection targets patient's cells rather than invading pathogens

Tumor-infiltrating lymphocytes may be good biomarker of response to trastuzumab in breast cancer

New study may pave way for more effective treatment for deadly childhood cancer

Budget cuts, years-long flat funding can delay research into effective treatments for cancer

Broad Medical Research Program, Crohn's & Colitis Foundation of America to merge together

Nanostring Technologies announces nationwide availability of Prosigna Breast Cancer Assay in 2014

New research project to genetically discriminate "identical" monozygotic twins

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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