Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Boost for cancer research in Leicestershire

A new approach to pain relief, investigation of a gene that triggers colorectal cancer and the prevention, early diagnosis and treatment of ovarian cancer are three research projects at the University of Leicester, which are to benefit from funding from the Leicestershire and Rutland charity Hope Against Cancer.

21 May 2008

Targeted therapy can improve outcomes for lung tumors

The first U.S. clinical trial using genetic screening to identify lung tumors likely to respond to targeted therapies supports the use of those drugs as first-line treatment rather than after standard chemotherapy has failed.

20 May 2008

Pfizer and Peter MacCallum support the future of cancer research in Australia

Australia's reputation for excellence in cancer research has been strengthened with the launch of the Peter MacCallum Pfizer Translational Oncology Research Collaborative Hub (TORCH) at the Peter MacCallum Cancer Centre, by the Minister for Innovation, Industry, Science and Research, Senator the Hon. Kim Carr.

18 May 2008

Scientists publish guidelines for the improved description of genomes and metagenomes

The Genomic Standards Consortium (GSC), an international initiative including representatives from a range of major sequencing and bioinformatics centres, has created a new guideline for describing genomes and metagenomes. The guideline, 'Minimum Information about a Genome Sequence' (MIGS), is published in the May issue of the journal Nature Biotechnology.

12 May 2008

Discovery of DNA variations in chromosome 6 that gives rise to neuroblastoma

Using advanced gene-hunting technology, an international team of researchers has for the first time identified a chromosome region that is the source of genetic events that give rise to neuroblastoma, an often fatal childhood cancer.

7 May 2008

Researchers report the cloning of a key group of human genes, the protein kinases

Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated.

2 May 2008

Breakthrough compound could lead to new class of antihypertensive drugs

University of Florida researchers have identified a drug compound that dramatically lowers blood pressure, improves heart function and - in a remarkable finding - prevents damage to the heart and kidneys in rats with persistent hypertension

1 May 2008

Human protein may offer novel target for blocking HIV infection

A research group supported by the National Institutes of Health (NIH) has uncovered a new route for attacking the human immunodeficiency virus (HIV) that may offer a way to circumvent problems with drug resistance. In findings published today in the online edition of the Proceedings of the National Academy of Sciences, the researchers report that they have blocked HIV infection in the test tube by inactivating a human protein expressed in key immune cells.

29 Apr 2008

Researchers identify Heme detoxification protein - potential target for developing new malaria drugs

Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified Heme Detoxification Protein (HDP), a unique protein encoded in the malaria genome that represents a potential target for developing new malaria drugs.

24 Apr 2008

Discovery of gene behind clefting disorder Branchio-Oculo-Facial syndrome

In a collaborative effort, researchers from Boston University School of Medicine (BUSM) have discovered that deletions or mutations within the TFAP2A gene (Activating Enhancer-Binding Protein) result in the distinctive clefting disorder Branchio-Oculo-Facial syndrome (BOFS).

23 Apr 2008

GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

20 Apr 2008

A genetic variation mimics effect of heart failure medications - may explain why beta-blockers do not work for all patients

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. That's the conclusion of a research team led by investigators at the University of Maryland School of Medicine in Baltimore and the Washington University School of Medicine in St. Louis.

20 Apr 2008

Two new clinical trials show promise for basal cell carcinoma and pancreatic cancer

Clinical researchers at Scottsdale Healthcare and TGen have announced the results of two clinical trials that show promise for patients battling cancer.

16 Apr 2008

New strategy rapidly describes outbreak strains with next-generation DNA sequencing

In the event of an outbreak or a bioterrorist attack, rapid identification of the genetic changes responsible for virulence or drug resistance is essential to mounting an effective response.

11 Apr 2008

Genetic test offers clues about cardiac hypertrophy in children

A mechanic uses diagnostic tests to determine why your engine is making strange sounds before lifting a wrench to fix the problem.

10 Apr 2008

New web portal, the PSI Structural Genomics Knowledgebase to advance protein studies

The Protein Structure Initiative (PSI), an effort supported by the National Institutes of Health (NIH), has launched an online resource that will enable scientists from across biomedical disciplines to easily access a wealth of information about proteins and to speed discovery about these molecules.

4 Apr 2008

Genomics News and Research

Further Reading

Boost for cancer research in Leicestershire

Targeted therapy can improve outcomes for lung tumors

Pfizer and Peter MacCallum support the future of cancer research in Australia

Scientists publish guidelines for the improved description of genomes and metagenomes

Discovery of DNA variations in chromosome 6 that gives rise to neuroblastoma

Researchers report the cloning of a key group of human genes, the protein kinases

Breakthrough compound could lead to new class of antihypertensive drugs

Human protein may offer novel target for blocking HIV infection

Researchers identify Heme detoxification protein - potential target for developing new malaria drugs

Discovery of gene behind clefting disorder Branchio-Oculo-Facial syndrome

GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

A genetic variation mimics effect of heart failure medications - may explain why beta-blockers do not work for all patients

Two new clinical trials show promise for basal cell carcinoma and pancreatic cancer

New strategy rapidly describes outbreak strains with next-generation DNA sequencing

Genetic test offers clues about cardiac hypertrophy in children

New web portal, the PSI Structural Genomics Knowledgebase to advance protein studies

Researchers urge ethics guidelines for human-genome research

Insulin-like growth factor found to have new role in development of brain's smell center

Beetle genome opens the door to developmental research

Neuronal regulators offer potential targets for cancer

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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