Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Sigma-Aldrich licenses RNAi patent estate from Alnylam

Sigma-Aldrich Corporation and Alnylam Pharmaceuticals announced today that Alnylam has granted Sigma-Aldrich a non-exclusive license to provide research products and services in RNA interference (RNAi) under the Kreutzer-Limmer patent family.

19 Jul 2005

Would boosting the oxytocin (OT) hormonal system lead to longer breast-feeding?

There's little controversy about the benefits of breastfeeding infants over giving them formula. Mother's milk is the perfect food, providing exactly the correct nourishment for newborns, while protecting them from many illnesses.

19 Jul 2005

Hormonal signaling systems and their role in sex drive

Two University of Edinburgh professors from the Centre for Integrative Physiology describe how "our understanding of how the brain processes information is undergoing a radical shift as we begin to recognize the implications of hormonal signaling systems within the brain itself," explained Gareth Leng.

19 Jul 2005

Scientists determine the structures of eight proteins in just 10-20 days per protein

A University at Buffalo scientist created a stir in 2003 when he announced a much faster, more precise and far less expensive method of obtaining nuclear magnetic resonance (NMR) data to map a protein's atomic structure. Genomics researchers were fascinated, but some also were a bit skeptical.

18 Jul 2005

Extraordinary number of genes are required for prenatal mammalian development

A team of scientists led by Cornell University's Dr. John Schimenti reports today that an extraordinary number of genes are required for prenatal mammalian development. The researchers estimate that up to 19% of all genes are vital for embryogenesis in mice.

17 Jul 2005

Researchers modify software to predict gene transcription

A modification to an "ace" gene prediction program by computer scientists at Washington University in St. Louis now enables scientists to predict the very beginnings of gene transcription start sites and where the first splice occurs thereby defining the first exon of the gene.

13 Jul 2005

Genes play an overriding role in cholesterol response

Why does it seem like some people can eat all the ice cream they want without increasing their cholesterol or gaining much weight, while others with high cholesterol have to watch their diets like a hawk? Because no matter what their lifestyle, people's genes play an overriding role in their cholesterol response.

11 Jul 2005

Tricirbine may help fight cancers

H. Lee Moffitt Cancer Center & Research Institute, working in partnership with the University of South Florida (USF), has discovered a new use for an old, previously discredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

Rosetta Genomics identifies hundreds of novel human microRNAs

In a study published online this week and to be published as a cover story in the July issue of Nature Genetics, Rosetta Genomics' scientists report identification of hundreds of human microRNA genes, including the first report of primate specific microRNAs.

21 Jun 2005

Scientists have tracked down the biological trigger that gives rise to Van Buchem disease

...a hereditary, disfiguring bone disorder that can cause blindness and deafness. The findings provide insight into long-range gene regulation and could lead to new treatments for osteoporosis and other crippling bone disorders.

16 Jun 2005

Discovery of molecular mechanism that seems to play an important role in Alzheimer's disease

An international team of chemists and molecular biologists has discovered a fundamental molecular mechanism that seems to play an important role in Alzheimer's disease, Parkinson's disease, mad cow disease and two-dozen other degenerative and fatal diseases.

8 Jun 2005

New series of human drug targets available to all researchers

The Structural Genomics Consortium (SGC), an Anglo-Canadian charitable consortium of public and private agencies including Oxford University, announced recently that it has delivered its first 50 human and malaria protein structures into the public domain on budget and two months ahead of schedule.

6 Jun 2005

Activation of thermoreceptors mediates raw garlic's burning pungency

The worldwide popularity of garlic as a food ingredient and its therapeutic stature in folklore both stem in part from the distinctive pungency associated with its raw, uncooked state.

23 May 2005

Researchers to explore genome of disease-fighting fungus

A team of Texas Agricultural Experiment Station scientists will soon begin genome sequencing a disease-fighting fungus used to protect crops, which has implications for both agriculture and the pharmaceutical industry.

15 May 2005

Humans more prone to cancer than chimpanzees

Chimpanzees and humans share a common ancestor, and even today 99 percent of the two species' DNA is identical. But since the paths of man and chimp diverged 5 million years ago, that one percent of genetic difference appears to have changed humans in an unexpected way: It could have made people more prone to cancer.

15 May 2005