Glucagon News and Research

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GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification.

31 Oct 2019

Researchers identify circuit that links cigarette smoking and risk of developing diabetes

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a circuit in rats that links cigarette smoking and the risk of developing type 2 diabetes, according to a study featured on the cover of the October 17 issue of Nature.

16 Oct 2019

Monitoring the Human Proteome using diaPASEF

In this interview, Dr. Hannes Röst describes how his lab are using diaPASEF to monitor the human proteome throughout a person's lifetime, and how machine learning could be used to analyze the data.

From Bruker Life Sciences Mass Spectrometry 25 Sep 2019

Early combination therapy provides long-term benefits for patients with type 2 diabetes

A new study, VERIFY (Vildagliptin Efficacy in combination with metfoRmIn For earlY treatment of type 2 diabetes) presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona, Spain (16-20 Sept, 2019), and published simultaneously in The Lancet, is the first to show that early combination therapy using vildagliptin and metformin in patients newly diagnosed with type 2 diabetes (T2D) leads to better long-term blood sugar control and a reduced rate of treatment failure than metformin alone.

19 Sep 2019

New insight into origin of diabetes in overweight patients

In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing. Obesity, by promoting the resistance to the action of insulin - one of the hormones that regulate blood sugar levels - is a major risk factor.

12 Sep 2019

Quick action can save lives of people with severe hypoglycemia

People with diabetes and their friends and relatives will be better prepared to spot the signs of dangerously low blood sugar using new resources the Hormone Health Network has introduced.

11 Sep 2019

Insulin imbalance may not be the only cause of diabetes

In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing.

11 Sep 2019

New injection helps reduce body weight, glucose levels in patients with obesity

An injection has helped reduce body weight and glucose levels in patients with diabetes and obesity in four weeks.

6 Aug 2019

SGLT-2 inhibitors do not increase the risk of UTIs in diabetics, concludes study

A new study has shown that SGLT-2 inhibitors used in the treatment of type 2 diabetes do not increase the risk of UTIs over other anti-diabetic medications.

31 Jul 2019

FDA approves first nasal glucagon therapy for treatment of severe hypoglycemia

The U.S. Food and Drug Administration today approved Baqsimi nasal powder, the first glucagon therapy approved for the emergency treatment of severe hypoglycemia that can be administered without an injection.

24 Jul 2019

Researchers find a potential modulator in revascularization of pancreatic islets

The first cause of the loss of functionality in transplanted pancreatic islets is the low capacity to create new vessels to allow the arrival of nutrients in the cells.

20 Jun 2019

FDA approves first non-insulin drug for treatment of pediatric patients with type 2 diabetes

The U.S. Food and Drug Administration today approved Victoza (liraglutide) injection for treatment of pediatric patients 10 years or older with type 2 diabetes.

18 Jun 2019

Diabetes drug reduces cardiovascular events and kidney problems, study finds

A clinical trial that followed more than 9,900 people in 24 countries has found that the drug dulaglutide reduced cardiovascular events and kidney problems in middle-aged and older people with Type 2 diabetes.

10 Jun 2019

Insulin-producing beta cells can change their function in diabetes, reveals study

A revolutionary new study using only materials derived from humans has revealed that insulin-producing beta cells can change their function in diabetes - and that this change may be reversible.

17 May 2019

Diabetes drug could help with smoking cessation

Phillip Robinson has gone from 10 cigarettes a day to one or two every other day after enrolling in a smoking cessation clinical trial launched by researchers at The University of Texas Health Science Center at Houston

30 Apr 2019

New discovery could provide opportunity to improve blood glucose control

Many diabetes patients do not only have problems with their insulin, but also with the release of the hormone glucagon. Researchers at Uppsala University have now discovered a regulation mechanism which could provide an opportunity to improve blood glucose control in these patients.

26 Apr 2019

New review on relationship between COPD and Type 2 diabetes

Chronic obstructive pulmonary disease is characterized by a chronic airflow obstruction that is associated with severe global mortality and morbidity.

23 Apr 2019

Older adults with type 1 diabetes have hypoglycemia over an hour a day

Older adults with type 1 diabetes typically have low blood sugar, or hypoglycemia, for more than an hour a day, suggests research to be presented Monday, March 25 at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La.

25 Mar 2019

Diabetes' sworn enemy could also be a protective asset

Montreal research team unravels an adaptive mechanism involved in controlling insulin action, showing that glucagon plays a crucial part in it and can thus be a protective asset.

6 Mar 2019

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

The body's ability to adapt to changing conditions and shifting physiologic demands is essential to survival. To do so, each cell must be able to dispose of damaged or unnecessary proteins--a quality-control mechanism critical for cellular performance and for the health of the entire organism.

21 Feb 2019