Glucose News and Research

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Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

A pathway activated in cancer plays an unexpected key role in metabolic diseases like type 2 diabetes, according to a study by researchers at Children's Hospital Boston. Evidence that the Lin28/let-7 pathway influences the cellular response to glucose provides a unifying theme to perplexing data that associates human genetic variation with diabetes risk.

30 Sep 2011

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Intensive control of blood sugar levels beyond standard targets provides no additional protection against cognitive decline in older people with diabetes than standard treatment, according to a national study coordinated by researchers at Wake Forest Baptist Medical Center.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Aggressive glycemic control does not improve clinical outcomes for diabetic CABG patients

Surgeons from Boston Medical Center (BMC) have found that in diabetic patients undergoing coronary artery bypass graft (CABG) surgery, aggressive glycemic control does not result in any significant improvement of clinical outcomes as compared with moderate control.

28 Sep 2011

Physical activity improves arthritis symptoms in obese mice

Adding another incentive to exercise, scientists at Duke University Medical Center have found that physical activity improves arthritis symptoms even among obese mice that continue to chow down on a high-fat diet.

27 Sep 2011

UCSF, QuantiaMD develop new DiabetesIQ mobile phone app

A new interactive mobile phone app called DiabetesIQ, released this week, challenges people to test their knowledge of diabetes and to compete with one another as they learn about the complexities of the disease, which affects more than 25 million Americans, including 4 million Californians.

27 Sep 2011

Gene blockade could reverse type 2 diabetes: Study

Australian scientists report that they may be on the brink of reversing type 2 diabetes after a genetic discovery. The finding centers on how a particular gene responds to high-fat diets by disrupting insulin production in the pancreas and triggering diabetes.

26 Sep 2011

Ambrx, Bristol-Myers Squibb collaborate for novel biologics to treat heart failure and diabetes

Bristol-Myers Squibb Company and Ambrx, Inc. today announced a collaboration under which Bristol-Myers Squibb will receive exclusive worldwide rights to research, develop and commercialize biologics based on Ambrx's research surrounding the Fibroblast Growth Factor 21 protein, for potential use in treating type 2 diabetes, and the Relaxin hormone, for potential use in treating heart failure.

23 Sep 2011

GI Dynamics introduces EndoBarrier Gastrointestinal Liner in Austria

GI Dynamics, Inc. today announced the launch of the EndoBarrier Gastrointestinal Liner in Austria, the establishment of the first two Centers of Excellence and the treatment of patients at each new Center.

21 Sep 2011

Sleep deprivation may disrupt insulin secretion and glucose levels in obese teens

Obese teenagers who don't get the proper amount of sleep may have disruptions in insulin secretion and blood sugar (glucose) levels, say pediatric researchers. Their study suggests that getting a good night's sleep may stave off the development of type 2 diabetes in these adolescents.

21 Sep 2011

The obese can’t help but eat: Study

A new study suggests that brains of people who are obese may be wired differently for impulse control, such as resisting a doughnut when their blood sugar levels drop, compared with people who are not obese.

20 Sep 2011

Diabetes and dementia, connection found

A new study revealed that people with diabetes may be at an increased risk of developing dementia. Scientists have suspected the link between the two diseases for several years, but several experts say this latest study highlights how treating preventable diseases like diabetes and obesity may be useful in preventing the onset of dementia.

20 Sep 2011

Vigorous exercise results in stronger bones, reduced diabetes risk and less visceral fat

Cells in bone, fat and the pancreas appear to be talking to each other and one thing they likely are saying is, "Get moving."

20 Sep 2011

People with diabetes more likely to develop dementia

People with diabetes appear to be at a significantly increased risk of developing dementia, according to a study published in the September 20, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

20 Sep 2011

Phenex commences Px-102 first-in-man Phase I study for Metabolic Syndrome and NAFLD

Phenex Pharmaceuticals AG announced today the start of a first-in-man Phase I study with its clinical drug candidate Px-102, a synthetic non-steroidal FXR agonist. The volunteers of the first dose level received the drug and showed no signs of discomfort or other adverse effects.

19 Sep 2011

Prevalence of diabetes increases 30% over last four years in urban India

The prevalence of diabetes in urban India is accelerating at a rapid rate and now stands at 5.5 percent (just under 20 million people), compared with 4.6 percent in 2007 - equivalent to a 30 percent increase in actual population numbers over the last four years - according to new research by GfK HealthCare's Roper Global Diabetes Group. Moreover, a full 10 percent of these patients have been diagnosed in the past 12 months.

19 Sep 2011

OptiScan's new bedside glucose monitoring system receives European CE Mark

OptiScan Biomedical Corporation, a developer of innovative continuous glucose monitoring systems for use in intensive care units (ICU), today announced that the company's OptiScanner Automatic Bedside Glucose Monitoring System has received CE Mark certification for use in the European Union.

19 Sep 2011

NTNU genetic research shows best recipe to limit risk of lifestyle-related diseases

What should we eat? Answers abound in the international media, all of which rely on their interpretation of recent medical literature to come up with recommendations for the healthiest diet. But what if you could answer this question at a molecular level - what if you could find out how our genes respond to the foods we eat, and what this does to the cellular processes that make us healthy - or not? That's precisely what biologists at the Norwegian University of Science and Technology have done.

19 Sep 2011

Multiple abstracts on QNEXA presented at 47th EASD

VIVUS, Inc. today announced that multiple abstracts were presented at the 47th European Association for the Study of Diabetes (EASD) Annual Meeting in Lisbon, Portugal. The presentations highlighted the long-term beneficial effects of QNEXA treatment in metabolically-impaired patients with prediabetes, diabetes, and metabolic syndrome.

17 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Glucose News and Research

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

FOX06 protein contributes to liver overproduction of glucose in diabetes

Aggressive glycemic control does not improve clinical outcomes for diabetic CABG patients

Physical activity improves arthritis symptoms in obese mice

UCSF, QuantiaMD develop new DiabetesIQ mobile phone app

Gene blockade could reverse type 2 diabetes: Study

Ambrx, Bristol-Myers Squibb collaborate for novel biologics to treat heart failure and diabetes

GI Dynamics introduces EndoBarrier Gastrointestinal Liner in Austria

Sleep deprivation may disrupt insulin secretion and glucose levels in obese teens

The obese can’t help but eat: Study

Diabetes and dementia, connection found

Vigorous exercise results in stronger bones, reduced diabetes risk and less visceral fat

People with diabetes more likely to develop dementia

Phenex commences Px-102 first-in-man Phase I study for Metabolic Syndrome and NAFLD

Prevalence of diabetes increases 30% over last four years in urban India

OptiScan's new bedside glucose monitoring system receives European CE Mark

NTNU genetic research shows best recipe to limit risk of lifestyle-related diseases

Multiple abstracts on QNEXA presented at 47th EASD

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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