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How diabetes drives atherosclerosis

Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research. Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques.

14 Mar 2008

Study may aid pancreatic cancer patients' response to chemo drugs

Pancreatic cancer patients face the worst survival rates compared to all other forms of human cancer as the disease is nearly impossible to diagnose at an early stage when successful treatments might be possible.

1 Nov 2007

AGE-rich foods causes dysfunction linked to heart disease

A study in this month's Diabetes Care finds that ingesting food or drink rich in advanced glycation end products (AGEs) causes immediate, short-lived but significant endothelial dysfunction, shedding light on the mechanism by which dietary AGE content can be linked to cardiovascular disease.

27 Sep 2007

Don't drink the fizzy stuff!

Drinking more than one soft drink daily whether it's regular or diet may be associated with an increase in the risk factors for heart disease, Framingham researchers reported in Circulation: Journal of the American Heart Association.

24 Jul 2007

Reactive oxygen species mediate a cellular 'memory' of high glucose stress signaling

Researchers at the University of Warwick’s Warwick Medical School have uncovered a process that locks the body’s metabolism in a diabetic state after only relatively limited exposure to high glucose levels.

29 Jun 2007

Chronic methamphetamine abuse linked to cardiovascular disease

The study is being published the week of June 25 in an advanced online edition of the Proceedings of the National Academy of Sciences.

26 Jun 2007

How your food is cooked may be as important to your health as the food itself

Researchers now know more about a new class of toxins that might soon become as important a risk factor for heart disease and metabolic disorders as trans fats.

25 Apr 2007

Steam, boil, stew for food preparation

How your food is cooked may be as important to your health as the food itself. Researchers now know more about a new class of toxins that might soon become as important a risk factor for heart disease and metabolic disorders as trans fats.

25 Apr 2007

Chuck out the barbecue!...toxins produced damage the health

Just as summer is coming in and many are dusting off the barbecue a new study says barbecued food may not be that healthy.

24 Apr 2007

Glyoxalase I protects proteins against damage by oxidation and nitration

Protein degradation and malfunction is a major cause of ageing and can be the result of attacks on proteins by other molecules.

2 Apr 2007

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

Alagebrium may prevent arterial aging in patients with systolic hypertension

A compound called alagebrium, which is very similar to another used in anti-wrinkle creams, may be useful in reducing the deleterious effects of arterial aging in the majority of elderly Americans with systolic hypertension, a new study from researchers at Johns Hopkins shows.

5 Dec 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

65 percent of America’s adults are overweight and 31 percent of adults are obese and at risk for chronic diseases

Government and private sector health experts now estimate that 65 percent of America’s adults are overweight and 31 percent of adults are obese and at risk for chronic diseases such as diabetes and hypertension. The link between obesity and hypertension is well known, but the exact nature of the association between the two disorders remains unclear.

11 Jun 2004