Glycoprotein News and Research

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CAR T-cell therapy may be viable treatment option for heart disease

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease.

12 Sep 2019

Measles back in UK three years after elimination

The United Kingdom was declared to be free of measles infection three years back in 2016 by the World Health Organization (WHO). In a recent development, due to the increasing number of cases of measles among unvaccinated children, the WHO has declared that UK can no longer be called measles-free.

20 Aug 2019

Study reveals Lassa virus' soft spot

As this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year, uncounted in rural villages throughout West Africa.

9 Aug 2019

Ultrasensitive method for direct detection of circulating tumor cells in blood

Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity.

8 Aug 2019

Researchers explain how 'viral' agents of neurological diseases ended up in our DNA

What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?

11 Jul 2019

Engineered stem cells offer new treatment for metastatic bone cancer

Engineered stem cells could help treat metastatic cancers in bone without killing normal surrounding bone.

9 Jul 2019

UVA launches Fibrosis Initiative to fight the growing cause of death

Fibrosis is often associated with many of the fatal diseases that pervade our globe, riddling organs with stiff tissue that diminishes their flexibility and leads to their failure.

21 Jun 2019

Scientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research

Researchers have developed three novel FACS protocols that can be used to isolate neural progenitors, astrocytes, and neurons from infected cerebral organoids.

19 Jun 2019

Researchers find more effective way to treat drug-resistant cancers

Researchers at SMU's Center for Drug Discovery, Design and Delivery have succeeded in lab testing the use of chemotherapy with a specific protein inhibitor so that the chemotherapeutic is better absorbed by drug-resistant cancer cells without harming healthy cells.

10 Jun 2019

Study describes new viral molecular evasion mechanism used by cytomegalovirus

A study published in the journal PLOS Pathogens describes a new viral molecular evasion mechanism used by cytomegalovirus to interfere in the immune response of the infected host.

30 Apr 2019

Stem cells in hair follicles have potential to regenerate myelin sheath that coats neurons

A subset of the stem cells in hair follicles have the potential to regenerate the coating that insulates neurons in mice, reports Thomas Hornyak of the VA Maryland Health Care System and the University of Maryland School of Medicine and colleagues, in a new study published 24th April in PLOS Genetics.

25 Apr 2019

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Two top researchers at the Ohio University Heritage College of Osteopathic Medicine are working with two other institutions on a federally funded project to investigate why Hispanics are more prone to develop non-alcoholic fatty liver disease.

12 Apr 2019

Plasma protein may hold potential for making wound-healing tissue scaffolds

Researchers in Germany have employed a plasma protein found in blood to develop a new method for making wound-healing tissue scaffolds.

4 Mar 2019

Universal pan-filovirus T-cell vaccine could offer protection against Ebola and Marburg

Vaccines that induce protective T-cell responses could protect against members across the filovirus family, according to a study published February 28 in the open-access journal PLOS Pathogens by Tomáš Hanke of the University of Oxford, Bette Korber of the Los Alamos National Laboratory, and colleagues.

4 Mar 2019

Custom-made proteins could result in antibodies that fight HIV

Researchers have developed a new method for the creation of custom-made proteins that can bypass the protective coating of the HIV virus.

28 Feb 2019

New PET/CT tracer shows high detection rate for diagnosis of acute venous thromboembolism

A first-in-human study featured in the February issue of The Journal of Nuclear Medicine reports that the novel positron emission tomography/computed tomography tracer 18F-GP1 showed excellent image quality and a high detection rate for the diagnosis of acute venous thromboembolism.

18 Feb 2019

Researchers uncover new mechanism of how Ebola viruses escape immune system

A research team from Tübingen and Göttingen has described in the renowned journal Cell Reports a new mechanism how the Ebola virus escapes the immune system.

12 Feb 2019

Investigational Ebola treatment found to be safe in adults

The investigational Ebola treatment mAb114 is safe, well-tolerated, and easy to administer, according to findings from an early-stage clinical trial published in The Lancet.

25 Jan 2019

Sleeping sickness parasite exhibits metabolic flexibility and adaptability

Parasitic protozoa called trypanosomes synthesize sugars using an unexpected metabolic pathway called gluconeogenesis, according to a study published December 27 in the open-access journal PLOS Pathogens by David Horn of the University of Dundee in the UK, and colleagues.

28 Dec 2018

New review focuses on the structure-activity relationships of flavonoids

ABCB1 in the ABC transporter family also termed as P-glycoprotein, grants the simultaneous resistance of metastatic cancer cells towards various anti-cancer drugs with different targets and diverse chemical structures.

27 Dec 2018