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Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Scientists determine normal function of gene associated with ALS and FTD

The normal function of a gene associated with the neurodegenerative diseases amyotrophic lateral sclerosis and frontotemporal dementia has been determined for the first time by University of Bath scientists.

24 Oct 2018

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma - the second most common bone cancer in children and young adults - unleashes tumor growth.

2 Aug 2018

Researchers use guide RNAs to improve base editing system

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

1 Aug 2018

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments.

27 Jul 2018

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.

20 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

The California Institute for Regenerative Medicine board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy.

30 Jun 2018

Research identifies new genetic variations that could indicate higher prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent.

12 Jun 2018

New shape of DNA found in human cells

DNA double helix discovery is one of the major breakthroughs in human scientific history. Now in a new research, scientists have found that there may be another new shape in the DNA machinery within the cells of humans.

25 Apr 2018

Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Researchers develop technology to program DNA for delivering cancer drugs

DNA has an important job – it tells your cells which proteins to make. Now, a research team at the University of Delaware has developed technology to program strands of DNA into switches that turn proteins on and off.

19 Mar 2018

Quiescent cells also acquire particular type of mutation, research shows

For almost a hundred years, geneticists have believed that the more a cell divides the more mutations it acquires. However, research by scientists at the Institut Pasteur shows that quiescent cells, which do not divide, also acquire a particular type of mutation - deletions (mutations through loss of nucleobases).

27 Feb 2018

Study reveals the mechanism of common DNA mutations

Researchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged.

2 Feb 2018

Genes in Space-3 team identifies microbes in real time aboard the space station

Being able to identify microbes in real time aboard the International Space Station, without having to send them back to Earth for identification first, would be revolutionary for the world of microbiology and space exploration.

29 Dec 2017

Epigenetics: A New Tool for Forensic Detectives

Developing analytical methods can help the triers of fact, judges and juries, better understand the events surrounding the circumstances of a crime. In forensic analysis, we are talking about determining the identity of unknown individuals through DNA and using DNA and other chemical signatures to determine and clarify the circumstances of the crime.

From Pittcon 20 Dec 2017

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

CRISPR - a genetic editor - used to edit DNA and RNA in two parallel studies

Two different studies have shown that CRISPR - a gene editing tool, could be the next big thing in manipulating and modifying the DNA to suit the needs.

26 Oct 2017

Space radiation causes long-term health consequences for astronauts

While people protect their eyes from the sun's radiation during a solar eclipse, NASA's Human Research Program is working to protect the whole human body from radiation in space. Space radiation is dangerous and one of the primary health risks for astronauts.

21 Sep 2017