Gynecology News and Research

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NIH panel recommends delivery options for women: VBAC or cesarean

An independent panel convened this week by the National Institutes of Health confronted a troubling fact that pregnant women currently have limited access to clinicians and facilities able and willing to offer a trial of labor after previous cesarean delivery because of so-called VBAC bans.

11 Mar 2010

Genomatix systems utilized to analyze cis and epigenetic elements that control reproductive events

The C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, at the Wayne State University School of Medicine, in collaboration with the Center for Molecular Medicine and Genetics, the Karmanos Cancer Institute and the Institute for Environmental Health Sciences, installed a Genomatix Mining Station and a Genomatix Genome Analyzer last year at their labs in Detroit, MI in order to support the analysis of Next Generation Sequencing (NGS) data.

11 Mar 2010

Cytokeratins 8 and 18 can strongly enhance breast cancer drug fulvestrant's anti-estrogenic activity

Women's responsiveness to the second-line breast cancer drug fulvestrant may depend on whether the cancer cells are expressing two key proteins, Indiana University Bloomington scientists report in this month's Cancer Biology & Therapy.

11 Mar 2010

First use of prenatal MRI to detect often-misdiagnosed CCD

In a case believed to be a United States first, the radiology team at Lucile Packard Children's Hospital has used prenatal magnetic resonance imaging to detect an often-misdiagnosed genetic disease.

10 Mar 2010

Bilateral oophorectomy may do more harm than good

Removal of the ovaries (bilateral oophorectomy) while performing a hysterectomy is common practice to prevent the subsequent development of ovarian cancer. This prophylactic procedure is performed in 55% of all U.S. women having a hysterectomy, or approximately 300,000 times each year. An article in the March/April issue of The Journal of Minimally Invasive Gynecology suggests that this procedure may do more harm than good.

10 Mar 2010

New article sheds light on the costs and benefits of screening for SMA

Spinal Muscular Atrophy is one of many serious disorders for which prenatal testing is available. SMA affects approximately 1 in 10,000 live births and is the leading genetic cause of infant mortality and the second most common autosomal recessive disorder, after cystic fibrosis. Although the American College of Medical Genetics recommends carrier testing for all couples, the American College of Obstetricians and Gynecologists has issued a recommendation to the contrary, citing lack of information about the costs and benefits of screening for SMA.

9 Mar 2010

Usage of gonadotropins in assisted reproductive technologies significantly improves outcomes

The U.S. infertility specialty has empirically incorporated greater amounts of human menopausal gonadotropin (hMG) into stimulation protocols, according to a new review article, "Gonadotropins in the Treatment of Infertility" by George T. Koulianos, MD, published in a recent issue of US Obstetrics & Gynecology, supported by an educational grant from Ferring Pharmaceuticals. The article reviews the wealth of clinical evidence supporting this trend, and demonstrates how the use of gonadotropins in the treatment of infertility, especially in assisted reproductive technologies, has significantly improved outcomes.

9 Mar 2010

Exposure to BPA during pregnancy causes permanent abnormalities in uterus of offspring

Researchers at Yale School of Medicine have discovered that exposure during pregnancy to Bisphenol A (BPA), a common component of plastics, causes permanent abnormalities in the uterus of offspring, including alteration in their DNA. The findings were reported in the March issue of Journal of the Federation of American Societies for Experimental Biology.

8 Mar 2010

New federal guidelines on breast cancer screening: Stanford experts disagree

At a recent community education program, Stanford experts on women’s cancer disagreed with controversial new federal guidelines on breast cancer screening. The new guidelines, released in November by the U.S. Preventive Services Task Force, would delay a woman’s first mammogram by 10 years, reduce future screenings from annual to every other year, and end them after age 74.

4 Mar 2010

ONA: Cutting 300,000 hours of RN care per year may affect quality of patient care

Ontario Nurses' Association President Linda Haslam-Stroud, RN is expressing deep concerns about the quality of patient care at The Ottawa Hospital following word that the facility is cutting approximately 300,000 hours of RN care per year.

27 Feb 2010

Nevirapine taken to protect fetus from HIV should be avoided for one year after childbirth, say researchers

Women given the human immunodeficiency virus (HIV) prevention drug nevirapine to protect their fetus should not use an HIV-drug regimen that contains nevirapine for at least one year after childbirth, say researchers at the University of Alabama at Birmingham.

25 Feb 2010

Excessive weight gain during pregnancy linked to increased risk of gestational diabetes

Women who gain excessive weight during pregnancy, especially in the first trimester, may increase their risk of developing diabetes later in their pregnancy, according to a study by the Kaiser Permanente Division of Research that appears online in the current issue of Obstetrics and Gynecology.

23 Feb 2010

Study shows prevalence of depression among low-income urban mothers

More than half of low-income urban mothers met the criteria for a diagnosis of depression at some point between two weeks and 14 months after giving birth, according to a study led by University of Rochester Medical Center researchers and published online by the journal Pediatrics.

19 Feb 2010

UCSF receives $1.15M grant to integrate family planning into HIV treatment and care

UCSF has received a $1.15 million grant from the Bill & Melinda Gates Foundation to determine if integrating family planning into HIV treatment and care will increase contraceptive use and decrease unintended pregnancy among HIV-positive women. UCSF will partner with the Kenya Medical Research Institute and Ibis Reproductive Health to conduct the research.

18 Feb 2010

Changes in vaginal pH make women more susceptible to infections

Changes in vaginal pH as a result of common “pH triggers” make women more susceptible to infections such as bacterial vaginosis (BV). Understanding how the vaginal environment responds to pH fluctuation helps health professionals prevent and treat these conditions.

18 Feb 2010

National symposium aims to attract more women for a rewarding career in surgery

While interviewing for postgraduate residency positions soon after giving birth to her third child, Dr. Sharona Ross recalls, she was very hesitant to bring up her infant and two small children at home. She thought it would hurt her chances for a career in surgery.

17 Feb 2010

Sequenom CMM launches SensiGene Fetal Sex Determination test

Sequenom, Inc. today announced the launch of the SensiGene™ Fetal(XY) (Fetal Sex Determination) test by Sequenom's CAP accredited and CLIA-certified laboratory, Sequenom Center for Molecular Medicine (Sequenom CMM). This is the company's second laboratory developed test powered by its SEQureDx™ technology.

17 Feb 2010

Infertility patients from across GTA demand government-funded IVF

Infertility patients from across the GTA gathered at Queen's Park this morning to demand government-funded in vitro fertilization (IVF). Larger than life children's building blocks on the steps of the provincial legislative building spelled out the $550 million the Ontario Expert Panel on Infertility and Adoption says the province could save in long term health care and social services costs by funding IVF.

16 Feb 2010

RI-MUHC and McGill University teams receive $5M CIHR grant for environmental and reproductive health studies

Two teams from the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University received significant support from the Canadian Institutes of Health Research (CIHR) amounting to $5 million over five years.

15 Feb 2010

Researcher receives $2.4M grant from NIH to study preeclampsia and diabetes in pregnant women

The link between obesity and high-risk pregnancies caused by preeclampsia and diabetes will be the focus of a $2.4 million National Institutes of Health research grant received by Sean Blackwell, M.D., associate professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at The University of Texas Medical School at Houston.

15 Feb 2010

Gynecology News and Research

NIH panel recommends delivery options for women: VBAC or cesarean

Genomatix systems utilized to analyze cis and epigenetic elements that control reproductive events

Cytokeratins 8 and 18 can strongly enhance breast cancer drug fulvestrant's anti-estrogenic activity

First use of prenatal MRI to detect often-misdiagnosed CCD

Bilateral oophorectomy may do more harm than good

New article sheds light on the costs and benefits of screening for SMA

Usage of gonadotropins in assisted reproductive technologies significantly improves outcomes

Exposure to BPA during pregnancy causes permanent abnormalities in uterus of offspring

New federal guidelines on breast cancer screening: Stanford experts disagree

ONA: Cutting 300,000 hours of RN care per year may affect quality of patient care

Nevirapine taken to protect fetus from HIV should be avoided for one year after childbirth, say researchers

Excessive weight gain during pregnancy linked to increased risk of gestational diabetes

Study shows prevalence of depression among low-income urban mothers

UCSF receives $1.15M grant to integrate family planning into HIV treatment and care

Changes in vaginal pH make women more susceptible to infections

National symposium aims to attract more women for a rewarding career in surgery

Sequenom CMM launches SensiGene Fetal Sex Determination test

Infertility patients from across GTA demand government-funded IVF

RI-MUHC and McGill University teams receive $5M CIHR grant for environmental and reproductive health studies

Researcher receives $2.4M grant from NIH to study preeclampsia and diabetes in pregnant women

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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