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Scientists discover how reverse transcriptase molecules interact with the HIV genome

Using ingenious molecular espionage, scientists have found how a single key enzyme, seemingly the Swiss army knife in HIV's toolbox, differentiates and dynamically binds both DNA and RNA as part of the virus' fierce attack on host cells. The work is described this week in the journal Nature.

7 May 2008

HIV drugs, Abacavir and Didanosine increase the risk of heart attack

A study to assess the adverse effects of anti-retroviral drugs shows that two widely-used HIV drugs are associated with an increased risk of heart attack/the formation of blood clots in the heart.

8 Feb 2008

HIV drug resistance risk in mothers reduced by tenofovir/emtricitabine with nevirapine during labor

New research from the University of Alabama at Birmingham (UAB) shows that adding a single dose of two common anti-HIV drugs can prevent HIV-positive pregnant women from developing resistance to an entire class of drugs, potentially improving future treatment options.

14 Nov 2007

Free medications ensure anti-HIV drugs are taken in Africa

HIV-infected patients in the African country of Tanzania were more likely to stop taking their medications and to fail treatment if they had to pay for the drugs themselves.

22 Oct 2007

FDA approves raltegravir new HIV drug

The U.S. Food and Drug Administration (FDA) has approved raltegravir tablets for treatment of Human Immunodeficiency Virus (HIV)-1 infection in combination with other antiretroviral agents in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

17 Oct 2007

HIV drug designed for children wins FDA approval

A pill containing 3 anti-HIV drugs designed specifically for children has been given tentative approval by the United States Food and Drug Administration (FDA). Its use in Sub-Saharan Africa will benefit thousands of children living with HIV.

10 Oct 2007

New Pfizer HIV drug approved for sale in Europe

Drug giant Pfizer has been given approval for it's new HIV drug Celsentri to go on sale in Europe.

24 Sep 2007

HIV protein both causes brain injury and prevents its repair

New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia.

17 Aug 2007

Tibotec Pharmaceuticals submits NDA for investigational HIV treatment

Tibotec Pharmaceuticals Ltd. has announced the submission of a New Drug Application to the U.S. Food and Drug Administration (FDA) for TMC125 (etravirine), an investigational non- nucleoside reverse transcriptase inhibitor (NNRTI), being studied for use with other antiretroviral (ARV) agents as a treatment for people infected with HIV- 1.

19 Jul 2007

Entecavir can compromise HIV treatment

Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal, according to a new report in the New England Journal of Medicine.

23 Jun 2007

Drug warning prompts treatment changes for those infected with hepatitis B and HIV

Cross-resistance alarms raised earlier this year by Johns Hopkins researchers about a widely used antiviral therapy for hepatitis B liver infections have prompted swift treatment revisions by the drug's maker and governmental agencies.

23 Jun 2007

First ever lung transplant on HIV patient performed in Italy

Italian surgeons have performed the world's first lung transplant on an HIV patient.

28 May 2007

FDA panel recommends new HIV drug Maraviroc

Approval is expected to be granted in the United States for a new drug to treat HIV infections.

24 Apr 2007

Resistance to anti-HIV drugs in Uganda developed due to drug supply problems

Some HIV-infected patients in Uganda who self-paid for their antiretroviral medications experienced interruptions in drug supply due to either financial demands or supply logistical disruptions.

24 Apr 2007

Natural ingredient in human blood found to block HIV-1

A new study has pinpointed a natural ingredient of human blood that effectively blocks HIV-1, the virus predominantly responsible for human AIDS, from infecting immune cells and multiplying.

20 Apr 2007

Natural blood ingredient prevents HIV

Scientists in Germany scientists say they have discovered a natural ingredient in human blood that prevents the HIV-1 virus from infecting immune cells.

19 Apr 2007

Too many of the world's poor still denied HIV drugs

According to a new report by the World Health Organization (WHO), UNAIDS and UNICEF, only 28% of the world's poor with HIV have access to the antiretroviral drugs that could save their lives.

17 Apr 2007

Health-care workers should undergo preventive drug treatment if exposed to HIV on the job

Doctors, nurses and other health-care providers have worried about HIV exposure since the AIDS epidemic first began in the early 1980s. Since the virus that causes AIDS is transmitted through blood, a simple needle stick could infect anyone treating a patient.

1 Mar 2007

Researchers identify cell line that is resistant to retroviruses

Researchers at the University of Minnesota have identified a protein that enables viruses such as HIV to infect cells and spread through the body.

17 Oct 2006

GSK to supply antiretroviral drugs to Russia at discounted price

GlaxoSmithKline has announced it would supply 90,000 packs of its antiretroviral drugs Combivir, Epivir and Ziagen to Russia at discounted prices by the end of 2006, the AFP/Yahoo! U.K and Ireland reports (AFP/Yahoo! U.K and Ireland, 9/15).

18 Sep 2006