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New clinical trial aims to examine safety and use of two HIV prevention tools

A clinical trial has begun to examine the safety and use of two HIV prevention tools--oral pre-exposure prophylaxis and a vaginal ring--in adolescent girls and young women in southern Africa.

8 Feb 2019

Faulty immune receptor in HIV patients could be reason why many experience complications

For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation.

7 Jan 2019

Breakthrough Alzheimer's discovery

A new study has found that the neurons in the brain can alter their genetic make-up unlike other cells of the body which remain constant.

22 Nov 2018

Scientists discover new molecular pathway that controls colorectal cancer development

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a new molecular pathway that controls colorectal cancer development, and their exciting findings open new therapeutic opportunities.

8 Oct 2018

Researchers develop rapid, cost-effective method to create human cortical organoids

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

7 Sep 2018

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

In a study, a new HIV drug reduced viral replication and increased immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with existing HIV medications, the drug is a promising strategy for patients who have run out of effective treatment options, the researchers said.

16 Aug 2018

Novel computer models for individualization of HIV therapy in countries with limited healthcare resources

New predictive computer models designed to optimize HIV therapy in countries with limited healthcare resources are published online this week in the Journal of Antimicrobial Chemotherapy.

11 Jun 2018

State-of-the-art HIV treatment regimen could save lives and prevent new infections in India

An HIV treatment regimen already widely used in North America and Europe would likely increase the life expectancy of people living with HIV in India by nearly three years and reduce the number of new HIV infections by 23 percent with minimal impact on the country's HIV/AIDS budget.

30 Apr 2018

New tool developed to protect women from HIV infection

Scientists at the University of Waterloo have developed a new tool to protect women from HIV infection.

16 Apr 2018

Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

FDA approves new antiretroviral medication for patients with multidrug-resistant HIV

Today, the U.S. Food and Drug Administration approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past (heavily treatment-experienced) and whose HIV infections cannot be successfully treated with other currently available therapies (multidrug resistant HIV, or MDR HIV).

6 Mar 2018

U.S.-funded global effort appears to reduce incidence of new HIV infections

A steep drop in the local incidence of new HIV infections accompanied the rollout of a U.S.-funded anti-HIV program in a large East-African population, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins School of Medicine.

30 Nov 2017

Desert soil analysis reveals treasure trove of microorganisms with potential to fight disease

Soils from one of the highest, driest places on earth harbor microorganisms with the potential to treat HIV and tackle the world's antibiotic time bomb, research from Newcastle University, UK, has revealed.

27 Nov 2017

Research shows high risk for cardiovascular and kidney disease in people with HIV

HIV patients and their doctors are urged to be more aware of the additional health risks associated with treated HIV infection. This follows new research that shows HIV patients at high risk for a heart attack or stroke are also at substantially greater risk for chronic kidney disease and vice versa.

7 Nov 2017

Gonorrhea and syphilis cases rise in Australia

The Annual Surveillance Report on HIV, viral hepatitis and sexually transmissible infections (STIs) in Australia was released and it revealed that there is a rise in diagnosis of gonorrhea and syphilis but the number of people being affected by HIV has plateaued. In addition tens of thousands of people have been cured of Hepatitis C. The report comes from the Kirby Institute at UNSW Sydney.

5 Nov 2017

Study: PrEP program for men who have sex with men could lead to long-term cost savings

Providing pre-exposure prophylaxis (PrEP) medication to men who have sex with men who are at high risk of HIV infection (equivalent to less than 5% of men who have sex with men at any point in time) in England would be cost-effective, and could help to prevent up to one in four cases of HIV, according to a study published in The Lancet Infectious Diseases journal.

19 Oct 2017

GW researcher awarded NIH grant to study how cocaine use affects HIV infection

Following studies showing that cocaine influences the replication and transcription of HIV, a researcher at the George Washington University School of Medicine and Health Sciences was awarded more than $2.3 million from the National Institutes of Health to look deeper into the involved molecular mechanisms that allow this effect to happen.

5 Oct 2017

USC scientist finds new approach to prevent HIV infection

Medical treatment that targets human proteins rather than ever-mutating viruses may one day help HIV-positive people whose bodies have built a resistance to "cocktails" currently used to keep them healthy, according to a Keck School of Medicine of USC researcher.

23 Aug 2017

Scientists create stem cell-based model of rare inherited neurological condition

An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS).

11 Aug 2017

Researchers investigate genetic mutations in sperm cells to help prevent birth defects

It's about preventing birth defects. Associate pharmaceutical sciences professor Wenfeng An and his team at South Dakota State University are investigating mobile DNA segments, known as L1s, in sperm cells with the goal to treat families at risk for genetic mutations before they conceive.

10 Aug 2017