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Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.

27 Sep 2005

Surprising immune system cells discovery

Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.

26 Sep 2005

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Workshop - stem cells in reproduction and in the brain

"Once we have found the factors by which body cells can be re-programmed into stem cells, then therapeutic cloning might become superfluous," said Hans R. Scholer, director of the Max Planck Institute for Molecular Biomedicine in Munster, Germany, at an international scientific symposium on stem cell research in Kobe, Japan.

10 Sep 2005

Hutchinson-Gilford progeria syndrome in children may be helped by cancer drugs

Children who suffer from a rare disease called progeria, which accelerates aging and often kills patients when they are in their teens, may possibly be helped by drugs being developed to treat cancer.

31 Aug 2005

Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

A class of anticancer drugs currently being evaluated in phase 3 clinical trials may also be an effective treatment for Hutchinson-Gilford progeria syndrome (HGPS), a fatal genetic disorder that causes premature aging.

29 Aug 2005

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

In a surprising development, a research team led by the National Human Genome Research Institute (NHGRI), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging.

29 Aug 2005

Pigment explains why red heads are more at risk of skin cancer

A team of scientists have discovered that tiny chemical differences in how our skin reacts to ultraviolet light could explain why red heads are more likely to suffer skin cancer.

29 Aug 2005

New technique for creating human embryonic stem cells

Researchers have developed a new technique for creating human embryonic stem cells by fusing adult somatic cells with embryonic stem cells. The fusion causes the adult cells to undergo genetic reprogramming, which results in cells that have the developmental characteristics of human embryonic stem cells.

22 Aug 2005

Scientists step closer to understanding the genetic pathway involved in the development of hearing

New research findings, published online in the journal Nature Genetics, detail how sensory hair cells in the ear - the cells largely responsible for hearing - develop unique shapes that enable the perception of sound.

22 Aug 2005

Loss of a gene called p63 accelerates aging in mice

Researchers have discovered that the loss of a gene called p63 accelerates aging in mice. Similar versions of the gene are present in many organisms, including humans. Therefore, the p63 gene is likely to play a fundamental biological role in aging-related processes.

17 Aug 2005

Analytical tool to help detect cancer

Scientists have long used ultra-fine glass tubes known as capillaries to analyze the chemical makeup of substances. Called capillary electrophoresis, or CE, the method applies high voltage to the capillaries, and by measuring the rate that the various materials move through the capillaries, researchers are able to identify individual compounds.

16 Aug 2005

New hope for those deaf from immune system attack

A new study may one day help those deafened by immune system attack, and possibly also lead to a test that could show which patients may be helped by immediate steroid treatment.

16 Aug 2005

Old-fashioned methods best at getting rid of head lice in children

Old-fashioned methods of getting rid of head lice in children are far more effective than current chemical treatments, researchers revealed recently.

15 Aug 2005

Body's own defense mechanism causes some of the most serious asthma symptoms

McGill University Health Centre (MUHC) scientists have discovered that our body's own defense mechanism causes some of the most serious asthma symptoms.

13 Aug 2005

Blondes may have fun but redheads can take the pain

According to a new British study, blondes may have more fun, but redheads are less likely to feel the pain.

10 Aug 2005

Wet combing four times more effective than chemical treatments for head lice

Fine combing of wet hair is far more effective than current over the counter chemical treatments for eliminating head lice, shows research published online by the British Medical Journal (BMJ) today.

4 Aug 2005

New laser therapy that destroys cancer cells but leaves healthy ones unharmed

Scientists at Stanford University have developed a new laser therapy that destroys cancer cells but leaves healthy ones unharmed. The new, non-invasive treatment is described in a study published in the Aug. 1 online edition of the Proceedings of the National Academy of Sciences (PNAS).

2 Aug 2005