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GSK strongly disagrees with conclusions reached in NEJM article on Avandia

GlaxoSmithKline has issued the following response to an article in the New England Journal of Medicine (NEJM) on Avandia (rosiglitazone maleate), a widely used and highly effective treatment for type 2 diabetes.

22 May 2007

Blood-thinning drugs need closer monitoring

Natalie Oake and colleagues report on a meta-analysis of studies that recorded hemorrhages and thromboembolic (blood clot) events in patients taking blood-thinners.

22 May 2007

FDA in trouble over widely used diabetic drug Avandia

A diabetes pill which has been widely used since 1999 is now suspected of increasing the risk of heart attacks for those taking it.

22 May 2007

First beating heart transplant procedure in the US

Protected by its own nutrients and blood supply, a beating heart supported by an investigational organ preservation device was successfully transplanted into a 47-year-old man with congestive heart failure and pulmonary hypertension on Sunday, April 8.

18 May 2007

Patients with myelodysplastic syndromes treated with Revlimid are living longer and remaining transfusion independent

New updated results from a pivotal Phase II trial evaluating Revlimid in patients with an incurable blood cancer known as myelodysplastic syndromes (MDS) were presented by Dr. Alan List, from the H. Lee Moffitt Cancer Center & Research Institute, at the 9th International Symposium on MDS currently taking place in Florence, Italy.

18 May 2007

Safer medical implants

A pair of Florida State University researchers have received a major grant from the National Institutes of Health (NIH) to study ways of preventing the body from developing scar tissue around biomedical devices such as coronary artery stents - a problem that affects thousands of patients each year.

18 May 2007

Quality improvement effort pays off in diabetes care

Spending money to improve diabetes care at federally qualified community health centers is a sound investment, according to one of the first studies to examine the clinical and economic impact of quality improvement on diabetes care.

18 May 2007

Long-term treatment with anti-clotting drug clopidogrel improves stenting outcomes in diabetic patients

A study showing that diabetic patients who are treated with long-term anti-clotting therapy are less likely to have a heart attack or die more than a year after stenting has been named among the best research papers presented at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI).

18 May 2007

Lowering a patient's temperature could aid standard stroke treatment

University of Cincinnati (UC) scientists have developed a model that could help physicians combine current clot-busting medication with below-normal body temperatures (hypothermia) to improve the treatment of ischemic stroke patients.

18 May 2007

Lipoic acid appears to slow down the process of aging

Researchers have identified the mechanism of action of lipoic acid, a remarkable compound that in animal experiments appears to slow down the process of aging, improve blood flow, enhance immune function and perform many other functions.

18 May 2007

Effects of Taser on human health

Using a Taser to control agitated suspects in police custody is standard operating procedure for many law enforcement agencies.

18 May 2007

Not enough is known about long-term safety of "functional foods"

So-called 'functional foods' need to be systematically monitored because not enough is known about their long-term safety and effectiveness, say a group of scientists writing in the British Medical Journal.

18 May 2007

Some NSAIDs may be better suited to treating cancer

Until recently, nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and celecoxib (sold as Celebrex), were being hailed as promising cancer prevention drugs.

18 May 2007

Stroke prevalence varies across U.S.

Stroke prevalence varies widely from state to state, with some states and U.S. territories having more than double the stroke prevalence of others, according to a new report from the Centers for Disease Control and Prevention (CDC).

18 May 2007

One kilogram higher birth weight associated with a 10-20% reduced risk of heart disease later in life

Dr Rachel Huxley, lead author of the paper and Acting Director of Nutrition and Lifestyle at The George Institute said, "Although there was support for a small association between birth weight and an individual's future risk of heart disease, the relationship is not as strong as earlier studies have suggested.

18 May 2007

Link between extreme sleep disorder and onset of parkinsonism or dementia

Mayo Clinic researchers and a group of international collaborators have discovered a correlation between an extreme form of sleep disorder and eventual onset of parkinsonism or dementia.

17 May 2007

Novel device helps monitor mental illness

Psychiatric researchers at the University of California, San Diego (UCSD) School of Medicine will report important new findings from a study of patients with bipolar affective disorder and schizophrenia at the upcoming meeting of the Society of Biological Psychiatry, to be held in San Diego May 17-20.

17 May 2007

Ottawa Aggressive Protocol for acute atrial fibrillation is successful

There is no consensus on Emergency Department management of acute atrial fibrillation (AAF) or atrial flutter (AAFL).

17 May 2007

Pycnogenol natural pine bark extract reduces heart failure

A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart.

17 May 2007

Merits and risks of postmenopausal hormone therapy

The study was categorized as a primary prevention trial for coronary heart disease, although the fact that mean age at recruitment was 63 years was not given enough importance at that time. WHI investigators concluded that hormone therapy (HT) was not cardioprotective, and, in fact, its riskbenefit ratio did not favor the use of postmenopausal hormones for prevention of chronic diseases.

17 May 2007